Results 41 to 50 of about 355,018 (412)

Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection

Nature Communications, 2022
Mycobacterium chelonae is a rare cause of chronic disseminated cutaneous infections in immunocompromised patients. Multidrug-resistant M. chelonae infections present a challenge for treatment, and prolonged antimicrobial courses lead to significant ...
J. Little, R. Dedrick, K. Freeman, Madison Cristinziano, Bailey E. Smith, C. Benson, T. Jhaveri, L. Baden, D. Solomon, G. Hatfull   +9 more
semanticscholar   +1 more source

Experimental test of connector rotation during DNA packaging into bacteriophage phi29 capsids [PDF]

, 2007
The bacteriophage phi29 generates large forces to compact its double-stranded DNA genome into a protein capsid by means of a portal motor complex. Several mechanical models for the generation of these high forces by the motor complex predict coupling of ...
Hetherington, Craig L., Craig L Hetherington, Falk, Wayne, Wayne Falk, Thorsten Hugel, Jardine, Paul J., Falk Wayne, Hugel Thorsten, Bustamante, Carlos, Grimes Shelley, Michaelis, Jens, Walter Jessica M, Bustamante Carlos, Michaelis Jens, Anderson, Dwight L., Hugel, Thorsten, Grimes, Shelley, Paul J Jardine, Jessica M Walter, Walter, Jessica M., Jardine Paul J, Dwight L Anderson, Jens Michaelis, Anderson Dwight L, Carlos Bustamante, Hetherington Craig L, Shelley Grimes   +26 more
core   +1 more source

Bacteriophage Therapy for Staphylococcus Aureus Infections: A Review of Animal Models, Treatments, and Clinical Trials

Frontiers in Cellular and Infection Microbiology, 2022
Staphylococcus aureus (S. aureus) is a common and virulent human pathogen causing several serious illnesses including skin abscesses, wound infections, endocarditis, osteomyelitis, pneumonia, and toxic shock syndrome. Antibiotics were first introduced in
Lucile Plumet, Nour Ahmad-Mansour, C. Dunyach-Rémy, K. Kissa, A. Sotto, J. Lavigne, Denis Costechareyre, V. Molle   +7 more
semanticscholar   +1 more source

The Presence of Bacteriophages in the Human Body: Good, Bad or Neutral?

Microorganisms, 2020
The presence of bacteriophages (phages) in the human body may impact bacterial microbiota and modulate immunity. The role of phages in human microbiome studies and diseases is poorly understood.
Marzanna Łusiak-Szelachowska, Beata Weber-Dąbrowska, Maciej Żaczek, Jan Borysowski, Andrzej Górski   +4 more
doaj   +1 more source

Potential for Phages in the Treatment of Bacterial Sexually Transmitted Infections

Antibiotics, 2021
Bacterial sexually transmitted infections (BSTIs) are becoming increasingly significant with the approach of a post-antibiotic era. While treatment options dwindle, the transmission of many notable BSTIs, including Neisseria gonorrhoeae, Chlamydia ...
Kathryn Cater, Ryszard Międzybrodzki, Vera Morozova, Sławomir Letkiewicz, Marzanna Łusiak-Szelachowska, Justyna Rękas, Beata Weber-Dąbrowska, Andrzej Górski   +7 more
doaj   +1 more source

Genomewide Patterns of Substitution in Adaptively Evolving Populations of the RNA Bacteriophage MS2 [PDF]

, 2009
Experimental evolution of bacteriophage provides a powerful means of studying the genetics of adaptation, as every substitution contributing to adaptation can be identified and characterized.
Charlesworth, Brian, Betancourt, Andrea J.   +1 more
core   +1 more source

Architecture and self-assembly of the jumbo bacteriophage nuclear shell

Nature, 2022
Bacteria encode myriad defences that target the genomes of infecting bacteriophage, including restriction–modification and CRISPR–Cas systems1. In response, one family of large bacteriophages uses a nucleus-like compartment to protect its replicating ...
Thomas G. Laughlin, A. Deep, Amy M. Prichard, C. Seitz, Yajie Gu, Eray Enustun, S. Suslov, Kanika Khanna, Erica A. Birkholz, Emily G. Armbruster, J. McCammon, Rommie E. Amaro, J. Pogliano, K. Corbett, E. Villa   +14 more
semanticscholar   +1 more source

In Vitro Evaluation of the Therapeutic Potential of Phage VA7 against Enterotoxigenic Bacteroides fragilis Infection

Viruses, 2021
Since the beginning of the 20th century, bacteriophages (phages), i.e., viruses that infect bacteria, have been used as antimicrobial agents for treating various infections. Phage preparations targeting a number of bacterial pathogens are still in use in
Nata Bakuradze, Maya Merabishvili, Khatuna Makalatia, Elene Kakabadze, Nino Grdzelishvili, Jeroen Wagemans, Cedric Lood, Irakli Chachua, Mario Vaneechoutte, Rob Lavigne, Jean-Paul Pirnay, Ivane Abiatari, Nina Chanishvili   +12 more
doaj   +1 more source

Novel bacteriophages containing a genome of another bacteriophage within their genomes [PDF]

, 2012
The work was funded by the Scottish Government’s Rural and Environment Science and Analytical Services (RESAS) DivisionA novel bacteriophage infecting Staphylococus pasteuri was isolated during a screen for phages in Antarctic soils.
Makarova Kira S., Koonin, Eugene V, Peter J Cock, Torrance Lesley, Kira S Makarova, Swanson, Maud M, Lesley Torrance, Torrance, Lesley, Reavy Brian, Hopkins, David W, Reavy, Brian, Hopkins, David W., Michael Taliansky, Cock, Peter J, Hopkins David W., Makarova, Kira S, Maud M Swanson, Swanson, Maud M., Makarova, Kira S., Koonin, Eugene V., Koonin Eugene V., Swanson Maud M., Taliansky, Michael, Cock Peter J., David W Hopkins, Taliansky Michael, Cock, Peter J., Brian Reavy, Eugene V Koonin   +28 more
core   +1 more source

Adsorption of MS2 bacteriophage on ultrafiltration membrane laboratory equipments [PDF]

, 2010
Virus adsorption has been quantified (i) on different materials including various containers made of glass, plastic or stainless steel and hollow fiber membranes made of polyethersulfone, polysulfone, PVDF or cellulose acetate (with two configurations ...
Causserand, Christel, Aimar, Pierre, Pierre, Gwenaelle, Roques, Christine   +3 more
core   +1 more source