Antibiotics, 2021 Bronisława Brandla Fejgin was a Polish-born Jewish female physician. Among Fejgin’s numerous articles in the field of microbiology, her later work was almost entirely devoted to phage research.
Andrzej Grzybowski +4 more
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Detection of intermediates and kinetic control during assembly of bacteriophage P22 procapsid [PDF]
, 2008 Bacteriophage P22 serves as a model for the assembly and maturation of other icosahedral double-stranded DNA viruses. P22 coat and scaffolding proteins assemble in vitro into an icosahedral procapsid, which then expands during DNA packaging (maturation).
Abendon +53 more
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Frontiers in Microbiology, 2020 American foulbrood is one of the most serious and yet unsolved problems of beekeeping around the world, because it causes a disease leading to the weakening of the vitality of honey bee populations and huge economic losses both in agriculture and ...
Ewa Jończyk-Matysiak +15 more
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Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process [PDF]
, 2017 Bacteriophages are bacterial viruses that infect the host after successful receptor recognition and adsorption to the cell surface. The irreversible adherence followed by genome material ejection into host cell cytoplasm must be preceded by the passage ...
Briers, Yves +4 more
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A viral genome packaging ring-ATPase is a flexibly coordinated pentamer
Nature Communications, 2021 In viruses, multi-subunit ring-ATPases are involved in genome packaging. Here, using single-molecule techniques, the authors determine that the active bacteriophage T4 DNA packaging motor is a pentamer and show that the motor can tolerate inactive ...
Li Dai +8 more
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ΦCrAss001 represents the most abundant bacteriophage family in the human gut and infects Bacteroides intestinalis [PDF]
, 2018 peer-reviewedCrAssphages are an extensive and ubiquitous family of tailed bacteriophages, predicted to infect bacteria of the order Bacteroidales. Despite being found in ~50% of individuals and representing up to 90% of human gut viromes, members of this
Draper, Lorraine A. +6 more
core +5 more sources
Phage-Phagocyte Interactions and Their Implications for Phage Application as Therapeutics
Viruses, 2017 Phagocytes are the main component of innate immunity. They remove pathogens and particles from organisms using their bactericidal tools in the form of both reactive oxygen species and degrading enzymes—contained in granules—that are potentially toxic ...
Ewa Jończyk-Matysiak +6 more
doaj +1 more source
Antibiotics targeting bacterial protein synthesis reduce the lytic activity of bacteriophages
Virus Research, 2022 Combination therapy of bacteriophages and antibiotics requires careful selection of specific antibiotics as it is crucial towards determining the success of phage therapy to treat multiple drug-resistant bacterial infections.
Medhavi Vashisth +5 more
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Dynamics of Bacteriophage Genome Ejection In Vitro and In Vivo
, 2010 Bacteriophages, phages for short, are viruses of bacteria. The majority of phages contain a double-stranded DNA genome packaged in a capsid at a density of ~500 mg/ml. This high density requires substantial compression of the normal B form helix, leading
Molineux, Ian J., Panja, Debabrata
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Alternative mechanism for bacteriophage adsorption to the motile bacterium Caulobacter crescentus [PDF]
, 2011 2D and 3D cryo-electron microscopy, together with adsorption kinetics assays of ϕCb13 and ϕCbK phage-infected Caulobacter crescentus, provides insight into the mechanisms of infection.
Ackermann +45 more
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