Results 11 to 20 of about 355,018 (412)
Recent advances in bacteriophage-based therapeutics: Insight into the post-antibiotic era
Acta Pharmaceutica Sinica B, 2022 Antibiotic resistance is one of the biggest threats to global health, as it can make the treatment of bacterial infections in humans difficult owing to their high incidence rate, mortality, and treatment costs.
Qiuhua Luo, Mengchi Sun, Jin Sun
exaly +4 more sources
Pharokka: a fast scalable bacteriophage annotation tool
Bioinform., 2022 Summary In recent years, there has been an increasing interest in bacteriophages, which has led to growing numbers of bacteriophage genomic sequences becoming available.
G. Bouras +5 more
semanticscholar +1 more source
Design of bacteriophage T4-based artificial viral vectors for human genome remodeling
Nature Communications, 2023 Designing artificial viral vectors (AVVs) programmed with biomolecules that can enter human cells and carry out molecular repairs will have broad applications.
Jingen Zhu +8 more
doaj +1 more source
Bacteriophage T4 Escapes CRISPR Attack by Minihomology Recombination and Repair
mBio, 2021 Bacteriophages (phages) are viruses that infect bacteria and use them as replication factories to assemble progeny phages. Bacteria have evolved powerful defense mechanisms to destroy the invading phages by severing their genomes soon after entry into ...
Xiaorong Wu +3 more
doaj +1 more source
Microorganisms, 2021 The authors emphasize how extremely important it is to highlight the role played by animal models in an attempt to determine possible phage interactions with the organism into which it was introduced as well as to determine the safety and effectiveness ...
Martyna Cieślik +3 more
doaj +1 more source
Human β-Defensin 2 and Its Postulated Role in Modulation of the Immune Response
Cells, 2021 Studies described so far suggest that human β-defensin 2 is an important protein of innate immune response which provides protection for the human organism against invading pathogens of bacterial, viral, fungal, as well as parasitical origin. Its pivotal
Martyna Cieślik +3 more
doaj +1 more source
Nature Communications, 2022 A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella pneumoniae infection after long-term (>700 days) antibiotic therapy is treated with a pre-adapted bacteriophage along with meropenem and colistin, followed by ceftazidime ...
Anaïs Eskenazi +17 more
semanticscholar +1 more source
Antibiotics, 2021 Acinetobacter baumannii are bacteria that belong to the critical priority group due to their carbapenems and third generation cephalosporins resistance, which are last-chance antibiotics.
Natalia Bagińska +3 more
doaj +1 more source
Frontiers in Microbiology, 2023 Bacteriophages, the most abundant organisms on earth, have the potential to address the rise of multidrug-resistant bacteria resulting from the overuse of antibiotics. However, their high specificity and limited host range can hinder their effectiveness.
Huang-Jie Jia +5 more
semanticscholar +1 more source
Biological Properties of 12 Newly Isolated Acinetobacter baumannii-Specific Bacteriophages
Viruses, 2023 Infections with the opportunistic Gram-negative bacterium Acinetobacter baumannii pose a serious threat today, which is aggravated by the growing problem of multi-drug resistance among bacteria, caused by the overuse of antibiotics.
Natalia Bagińska +7 more
doaj +1 more source