Results 11 to 20 of about 246,265 (316)
Recent advances in bacteriophage-based therapeutics: Insight into the post-antibiotic era
Acta Pharmaceutica Sinica B, 2022 Antibiotic resistance is one of the biggest threats to global health, as it can make the treatment of bacterial infections in humans difficult owing to their high incidence rate, mortality, and treatment costs.
Jin Sun, Zhonggui He, Qiuhua Luo
exaly +3 more sources
Design of bacteriophage T4-based artificial viral vectors for human genome remodeling
Nature Communications, 2023 Designing artificial viral vectors (AVVs) programmed with biomolecules that can enter human cells and carry out molecular repairs will have broad applications.
Jingen Zhu +8 more
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Bacteriophage T4 Escapes CRISPR Attack by Minihomology Recombination and Repair
mBio, 2021 Bacteriophages (phages) are viruses that infect bacteria and use them as replication factories to assemble progeny phages. Bacteria have evolved powerful defense mechanisms to destroy the invading phages by severing their genomes soon after entry into ...
Xiaorong Wu +3 more
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Microorganisms, 2021 The authors emphasize how extremely important it is to highlight the role played by animal models in an attempt to determine possible phage interactions with the organism into which it was introduced as well as to determine the safety and effectiveness ...
Martyna Cieślik +3 more
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Human β-Defensin 2 and Its Postulated Role in Modulation of the Immune Response
Cells, 2021 Studies described so far suggest that human β-defensin 2 is an important protein of innate immune response which provides protection for the human organism against invading pathogens of bacterial, viral, fungal, as well as parasitical origin. Its pivotal
Martyna Cieślik +3 more
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Antibiotics, 2021 Acinetobacter baumannii are bacteria that belong to the critical priority group due to their carbapenems and third generation cephalosporins resistance, which are last-chance antibiotics.
Natalia Bagińska +3 more
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How Interest in Phages Has Bloomed into a Leading Medical Research Activity in Poland
Viruses, 2022 Poland has a leading position in phage therapy, as reflected by the number of patients treated and relevant publications in quality journals. The Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences was established by Ludwik
Maciej Żaczek +5 more
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Transduction of bacteriophage lambda by bacteriophage T1 [PDF]
Journal of Virology, 1979 When bacteriophage T1 was grown on bacteriophage lambda-lysogenic cells, phenotypically mixed particles were formed which had the serum sensitivity, host range, and density of T1 but which gave rise to lambda phage. T1 packaged lambda genomes more efficiently both when the length of the prophage was less than that of wild-type lambda and when the host ...
H, Drexler, J R, Christensen
openaire +2 more sources
Microorganisms, 2020 Despite their simplicity, viruses can display social-like interactions such as cooperation, communication, and cheating. Focusing on bacteriophages, here we review features including viral product sharing, cooperative evasion of antiviral defenses, prudent host exploitation, superinfection exclusion, and inter-phage peptide-mediated signaling. We argue
Pilar Domingo-Calap +2 more
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Bacteriophages and antibiotic interactions in clinical practice: what we have learned so far
Journal of Biomedical Science, 2022 Bacteriophages (phages) may be used as an alternative to antibiotic therapy for combating infections caused by multidrug-resistant bacteria. In the last decades, there have been studies concerning the use of phages and antibiotics separately or in ...
Marzanna Łusiak-Szelachowska +10 more
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