Results 261 to 270 of about 434,771 (384)

Typing of Paratyphoid B Bacilli by Vi Bacteriophage [PDF]

, 1943
A. Felix, B. R. Callow
openalex   +1 more source

Draft genome sequencing and <i>in vitro</i> activity data of the lytic vB_EcoM_AMO3598 bacteriophage effective against multi - drug resistant <i>E. coli</i>. [PDF]

Data Brief
Alexyuk M, Bogoyavlenskiy A, Akanova K, Moldakhanov Y, Manakbayeva A, Kerimov T, Berezin V, Alexyuk P.   +7 more
europepmc   +1 more source

A Fast Path from Innovation to Safe and Effective Medicine

Clinical Pharmacology &Therapeutics, EarlyView.
Consistent progress in medicines development has allowed both for de novo treatment options and for the refinement of existing products that improve effectiveness or reduce harm. Nonetheless, unmet medical needs persist, particularly in rare diseases, pediatrics and underserved populations.
Peter Arlett, Falk Ehmann, Ralf Herold, Evdokia Korakianiti, Pierpaolo Moscariello, Liese Barbier, Iordanis Gravanis, Frank Pétavy, Emmanuel Cormier, Andrew Thomson, Spiros Vamvakas, Steffen Thirstrup   +11 more
wiley   +1 more source

Electron microscopy of Developing Bacteriophage, and other Viruses

, 1951
Ralph W. G. Wyckoff
openalex   +1 more source

ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. INFLUENCE OF BACTERIOPHAGE T2 ON THE SYNTHETIC PATHWAY IN HOST CELLS [PDF]

, 1959
Arthur Kornberg, Steven B. Zimmerman, S.R. Kornberg, John Josse   +3 more
openalex   +1 more source

Bacteriophages as a modern diagnostic tool: innovations, applications and challenges. [PDF]

Mol Biol Rep
Olszewska P, Spietelun M, Syguła K, Ossowski A, Grygorcewicz B.   +4 more
europepmc   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

THE MULTIPLICATION OF BACTERIOPHAGE IN VIVO AND ITS PROTECTIVE EFFECT AGAINST AN EXPERIMENTAL INFECTION WITH SHIGELLA DYSENTERIAE [PDF]

, 1943
René Dubos, June Hookey Straus, Cynthia Pierce   +2 more
openalex   +1 more source

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert, Kylee Kendra Marie Ronnenberg, Claudia Ruelker, Silke Spang, Naveed Honarvar, Robert Landsiedel   +5 more
wiley   +1 more source

Bacteriophages as an alternative strategy for the treatment of drug resistant bacterial infections: Current approaches and future perspectives. [PDF]

Cell Surf
Girma A.
europepmc   +1 more source