Phage Prevalence in the Human Urinary Tract—Current Knowledge and Therapeutic Implications
Recent metagenomic analyses imply an immense abundance of phages in the human body. Samples collected from different sites (lungs, skin, oral cavity, intestines, ascitic fluid, and urine) reveal a generally greater number of phage particles than that of ...
Maciej Żaczek+3 more
doaj +1 more source
Do Anti-Phage Antibodies Persist after Phage Therapy? A Preliminary Report
Phages are immunogenic and may evoke an immune response following their administration. Consequently, patients undergoing phage therapy (PT) produce phage-neutralizing serum antibodies.
Marzanna Łusiak-Szelachowska+5 more
doaj +1 more source
Draft Genome Sequence of an Enterococcus faecalis ATCC 19433 Siphovirus Isolated from Raw Domestic Sewage. [PDF]
We previously isolated and characterized an Enterococcus faecalis ATCC 19433 siphovirus from raw domestic sewage as a viral indicator of human fecal pollution.
Ly, Melissa+3 more
core +2 more sources
A potential concern with bacteriophage (phage) therapeutics is a host-versus-phage response in which the immune system may neutralize or destroy phage particles and thus impair therapeutic efficacy, or a strong inflammatory response to repeated phage ...
Helen R. Freyberger+4 more
doaj +1 more source
Innovating on Well Biofouling Remediation: A Bacteriophage Cocktail Approach [PDF]
Waller Creek Working ...
Bae, Sungwoo+3 more
core +1 more source
Antibacterial Efficacy of Two Commercially Available Bacteriophage Formulations, Staphylococcal Bacteriophage and PYO Bacteriophage, Against Methicillin-Resistant Staphylococcus aureus: Prevention and Eradication of Biofilm Formation and Control of a Systemic Infection of Galleria mellonella Larvae [PDF]
Sessile bacteria growing on surfaces are more resistant to standard antibiotics than their planktonic counterpart. Due to their antimicrobial properties, bacteriophages have re-emerged as a promising approach to treat bacterial biofilm-associated ...
Di Luca, Mariagrazia+4 more
core +1 more source
Potential for Phages in the Treatment of Bacterial Sexually Transmitted Infections
Bacterial sexually transmitted infections (BSTIs) are becoming increasingly significant with the approach of a post-antibiotic era. While treatment options dwindle, the transmission of many notable BSTIs, including Neisseria gonorrhoeae, Chlamydia ...
Kathryn Cater+7 more
doaj +1 more source
From DNA sequence to application: possibilities and complications [PDF]
The development of sophisticated genetic tools during the past 15 years have facilitated a tremendous increase of fundamental and application-oriented knowledge of lactic acid bacteria (LAB) and their bacteriophages.
A Bruttin+110 more
core +3 more sources
Diversity and function of phage encoded depolymerases [PDF]
Bacteriophages of the Podoviridae family often exhibit so-called depolymerases as structural components of the virion. These enzymes appear as tail spike proteins (TSPs).
Fieseler, Lars+2 more
core +1 more source
The Presence of Bacteriophages in the Human Body: Good, Bad or Neutral?
The presence of bacteriophages (phages) in the human body may impact bacterial microbiota and modulate immunity. The role of phages in human microbiome studies and diseases is poorly understood.
Marzanna Łusiak-Szelachowska+4 more
doaj +1 more source