Results 71 to 80 of about 298,637 (311)

Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]

, 2017
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core   +1 more source

Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study

Nature Microbiology
In contrast to the many reports of successful real-world cases of personalized bacteriophage therapy (BT), randomized controlled trials of non-personalized bacteriophage products have not produced the expected results.
J. Pirnay, S. Djebara, Griet Steurs, Johann Griselain, C. Cochez, Steven De Soir, T. Glonti, An Spiessens, Emily Vanden Berghe, Sabrina Green, J. Wagemans, C. Lood, Eddie Schrevens, N. Chanishvili, M. Kutateladze, Mathieu de Jode, P. Ceyssens, J. Draye, G. Verbeken, D. De Vos, T. Rose, J. Onsea, Brieuc Van Nieuwenhuyse, P. Soentjens, R. Lavigne, M. Merabishvili   +25 more
semanticscholar   +1 more source

Bacteriophage Applications for Food Production and Processing

Viruses, 2018
Foodborne illnesses remain a major cause of hospitalization and death worldwide despite many advances in food sanitation techniques and pathogen surveillance.
Zachary D. Moye, Joelle E. Woolston, A. Sulakvelidze   +2 more
semanticscholar   +1 more source

Direct comparison of nick-joining activity of the nucleic acid ligases from bacteriophage T4 [PDF]

, 2006
The genome of bacteriophage T4 encodes three polynucleotide ligases, which seal the backbone of nucleic acids during infection of host bacteria. The T4Dnl (T4 DNA ligase) and two RNA ligases [T4Rnl1 (T4 RNA ligase 1) and T4Rnl2] join a diverse array of ...
Amitsur, Arabshahi, Bebenek, Begley, Bellacosa, Blondal, Blondal, Cherepanov, Cherepanov, Clepet, Della, Desmond R. Bullard, Doherty, Engler, Fareed, Higgins, Ho, Ho, Kaufmann, Keppetipola, Kornberg, Kuhn, Lavesa-Curto, Lehman, Markham, Martins, Martins, Miller, Moore, Nandakumar, Nandakumar, Nandakumar, Nick McElhinny, Omari, Pascal, Pitcher, Pitcher, Richard P. Bowater, Rossi, Ruiz, Runnels, Rydberg, Sambrook, Sekiguchi, Shuman, Shuman, Snopek, Sriskanda, Stuart, Timson, Tomkinson, Wang, Wang, Weiss, Wilkinson, Wilkinson, Wilkinson, Wood, Wood, Worthey, Yin, Yin   +61 more
core   +4 more sources

Resistance Development to Bacteriophages Occurring during Bacteriophage Therapy

Viruses, 2018
Bacteriophage (phage) therapy, i.e., the use of viruses that infect bacteria as antimicrobial agents, is a promising alternative to conventional antibiotics.
Frank Oechslin
semanticscholar   +1 more source

Putative plasmid prophages of Bacillus cereus sensu lato may hold the key to undiscovered phage diversity

Scientific Reports, 2021
Bacteriophages are bacterial viruses and the most abundant biological entities on Earth. Temperate bacteriophages can form prophages stably maintained in the host population: they either integrate into the host genome or replicate as plasmids in the host
Emma G. Piligrimova, Olesya A. Kazantseva, Andrey N. Kazantsev, Nikita A. Nikulin, Anna V. Skorynina, Olga N. Koposova, Andrey M. Shadrin   +6 more
doaj   +1 more source

Highly Sensitive Bacteriophage-Based Detection of Brucella abortus in Mixed Culture and Spiked Blood

Viruses, 2017
For decades, bacteriophages (phages) have been used for Brucella species identification in the diagnosis and epidemiology of brucellosis. Traditional Brucella phage typing is a multi-day procedure including the isolation of a pure culture, a step that ...
Kirill V. Sergueev, Andrey A. Filippov, Mikeljon P. Nikolich   +2 more
doaj   +1 more source

What Are the Potential Benefits of Using Bacteriophages in Periodontal Therapy?

Antibiotics, 2022
Periodontitis, which may result in tooth loss, constitutes both a serious medical and social problem. This pathology, if not treated, can contribute to the development of, among others, pancreatic cancer, cardiovascular diseases or Alzheimer’s disease ...
Jan Kowalski, Renata Górska, Martyna Cieślik, Andrzej Górski, Ewa Jończyk-Matysiak   +4 more
doaj   +1 more source

Bacteriophage effect on parasitism resistance [PDF]

arXiv, 2022
Many studies have shown that the protection of the host $\it{Acyrthosiphon~pisum}$ (Hemiptera, Aphididae) against the parasitoid $\it{Aphidius~ervi}$ (Hymenoptera, Braconidae) is conferred by the interaction between the secondary endosymbiont $\it{Hamiltonella~defensa}$ and the bacteriophage $\it{APSE}$ ($\it{Acyrthosiphon~pisum}$ secondary ...
arxiv  

A mechanical model of bacteriophage DNA ejection [PDF]

, 2017
Single molecule experiments on bacteriophages show an exponential scaling for the dependence of mobility on the length of DNA within the capsid. It has been suggested that this could be due to the "capstan mechanism" -- the exponential amplification of friction forces that result when a rope is wound around a cylinder as in a ship's capstan.
arxiv   +1 more source