Results 51 to 60 of about 13,887 (173)

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

open access: yesChemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Harnessing cracks in metal films: Design strategies for stretchable conductors

open access: yesInfoMat, EarlyView.
In stretchable electronics, metal film‐based components function either as strain‐insensitive interconnects/electrodes or as strain‐sensitive sensors, both of which are governed by crack‐induced electromechanical responses, yet these two roles have often been discussed separately in previous reviews.
Ting Zhu, Kai Wu, Gang Liu, Jun Sun
wiley   +1 more source

Construction, Characterization, and Application of a Nonpathogenic Virus-like Model for SARS-CoV-2 Nucleocapsid Protein by Phage Display

open access: yesToxins, 2022
With the outbreak and spread of COVID-19, a deep investigation of SARS-CoV-2 is urgent. Direct usage of this virus for scientific research could provide reliable results and authenticity.
Yuting Wu   +5 more
doaj   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

open access: yesVIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang   +5 more
wiley   +1 more source

Development of a high-throughput method to screen novel antiviral materials.

open access: yesPLoS ONE, 2022
Respiratory infectious diseases pose a serious threat worldwide, and novel antiviral materials are highly demanded. Photocatalytic nanoparticles have been developed to inhibit indirect transmission of pathogens by acting as surface coating materials ...
Makoto Nakakido   +4 more
doaj   +1 more source

Initiation and termination signals for transcription in bacteriophage M13

open access: yesNucleic Acids Research, 1984
Transcription of the infrequently expressed phage M13 genome domain, comprising genes III, VI, I and IV, has been studied in detail by hybridization and S1-nuclease mapping studies. The contiguous genes III and VI are transcribed via an 1800 nucleotide-long RNA molecule that is initiated at a promoter which overlaps with the Rho-independent termination
M A, Smits   +3 more
openaire   +3 more sources

Deep Mutational Scanning for the Study and Engineering of Protein Assemblies

open access: yesChemistry–Methods, Volume 6, Issue 8, August 2026.
This review explores how deep mutational scanning (DMS) can be used to improve understanding and accelerate engineering of protein assemblies, from natural fibers to engineered nanocages. We discuss various types of protein assemblies and their characterization, provide an introduction to the DMS technique, and then highlight examples in which DMS has ...
Jenna B. Wolfanger   +2 more
wiley   +1 more source

Hybrid Nanomaterial Complexes for Advanced Phage-guided Gene Delivery

open access: yesMolecular Therapy: Nucleic Acids, 2014
Developing nanomaterials that are effective, safe, and selective for gene transfer applications is challenging. Bacteriophages (phage), viruses that infect bacteria only, have shown promise for targeted gene transfer applications.
Teerapong Yata   +6 more
doaj   +1 more source

Mass spectrometry enumeration of filamentous M13 bacteriophage

open access: yesAnalytical Biochemistry, 2019
In the last decade, filamentous M13 bacteriophage has emerged into numerous biotechnological applications as a promising nontoxic and self-assembling biomaterial with specific binding properties. This raises a question about its upscale production that consequently requires an accurate phage enumeration during the various protocol developments. However,
Tingting, Wang   +3 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy