Results 61 to 70 of about 17,136 (170)

An Engineered M13 Filamentous Nanoparticle as an Antigen Carrier for a Malignant Melanoma Immunotherapeutic Strategy

Viruses
Bacteriophages, prokaryotic viruses, hold great potential in genetic engineering to open up new avenues for vaccine development. Our study aimed to establish engineered M13 bacteriophages expressing MAGE-A1 tumor peptides as a vaccine for melanoma ...
Nuša Brišar, Katja Šuster, Simona Kranjc Brezar, Robert Vidmar, Marko Fonović, Andrej Cör   +5 more
doaj   +1 more source

Programmable Nanobody‐Targeting Chimeras Enable Intracellular Viral Protein Degradation

Advanced Science, Volume 13, Issue 53, 24 September 2026.
Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Max Yu‐Chen Pan, Ting‐Hui Lee, Tzu‐Ning Peng, Eva Yi‐Hsuan Wu, Yu‐Ting Chiu, Chih‐Chien Chiu, Hong Vinh Nguyen, Yuan‐Shao Pao, Ming‐Hong Chao, Richard Kuan‐Lin Lee, Han‐Chung Wu, Lily Hui‐Ching Wang   +11 more
wiley   +1 more source

Initiation and termination signals for transcription in bacteriophage M13

Nucleic Acids Research, 1984
Transcription of the infrequently expressed phage M13 genome domain, comprising genes III, VI, I and IV, has been studied in detail by hybridization and S1-nuclease mapping studies. The contiguous genes III and VI are transcribed via an 1800 nucleotide-long RNA molecule that is initiated at a promoter which overlaps with the Rho-independent termination
M A, Smits, J, Jansen, R N, Konings, J G, Schoenmakers   +3 more
openaire   +3 more sources

Piezo‐Coupling Effects in Smart Polymers: Toward Ultrasensitive Sensing and Biomedical Applications

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Piezo‐coupling effects are the foundational factors for the development of multifunctional and self‐powered platforms. Central to this advancement is the use of stimuli‐responsive smart polymers, which offer mechanical flexibility, biocompatibility, and simplified structural complexity with improved sensitivity and energy efficiency.
Duc Khanh Tran, Tuan Sang Tran, Thanh‐An Truong, Trung‐Hieu Vu, That Buu Ton, Dzung Viet Dao, Van Thanh Dau   +6 more
wiley   +1 more source

Mass spectrometry enumeration of filamentous M13 bacteriophage

Analytical Biochemistry, 2019
In the last decade, filamentous M13 bacteriophage has emerged into numerous biotechnological applications as a promising nontoxic and self-assembling biomaterial with specific binding properties. This raises a question about its upscale production that consequently requires an accurate phage enumeration during the various protocol developments. However,
Tingting, Wang, Ai, Nguyen, Linwen, Zhang, Illarion V, Turko   +3 more
openaire   +3 more sources

Harnessing cracks in metal films: Design strategies for stretchable conductors

InfoMat, Volume 8, Issue 9, September 2026.
In stretchable electronics, metal film‐based components function either as strain‐insensitive interconnects/electrodes or as strain‐sensitive sensors, both of which are governed by crack‐induced electromechanical responses, yet these two roles have often been discussed separately in previous reviews.
Ting Zhu, Kai Wu, Gang Liu, Jun Sun
wiley   +1 more source

Microbial Signals in Cancer: Dissecting Host–Microbiota–Tumor Interactions and Potential Therapeutic Strategy

MedComm, Volume 7, Issue 9, September 2026.
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu, Mengjuan Xuan, Liang Yu, Zhongyang Xie, Qingfei Chu, Shihui Wei, Tuokai Wang, Chen Xue, Lanjuan Li   +8 more
wiley   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

Homogenous M13 bacteriophage quantification assay using switchable lanthanide fluorescence probes

BioTechniques, 2012
We have developed a rapid and reliable bacteriophage quantification method based on measurement of phage single-stranded DNA (ssDNA) using switchable lanthanide chelate complementation probes.
Ari Lehmusvuori, Julius Manninen, Tuomas Huovinen, Tero Soukka, Urpo Lamminmäki   +4 more
doaj   +1 more source

Nicking Activity of M13 Bacteriophage Protein 2

International Journal of Molecular Sciences
Gene II Protein (Gp2/P2) is a nicking enzyme of the M13 bacteriophage that plays a role in the DNA replication of the viral genome. P2 recognizes a specific sequence at the f1 replication origin and nicks one of the strands and starts replication. This study was conducted to address the limitations of previous experiments, improve methodologies, and ...
Esma Aybakan, Tanil Kocagoz, Ozge Can
openaire   +2 more sources