Results 111 to 120 of about 129,818 (339)

Replication of plasmids derived from Shiga toxinconverting bacteriophages in starved Escherichia coli [PDF]

, 2011
The pathogenicity of Shiga toxin-producing Escherichia coli (STEC) depends on the expression of stx genes that are located on lambdoid prophages. Effective toxin production occurs only after prophage induction, and one may presume that replication of the
Nadratowska-Wesołowska, Beata, Nejman, Bożena, Szalewska-Pałasz, Agnieszka, Węgrzyn, Alicja, Węgrzyn, Grzegorz   +4 more
core  

RNA Viral Community in Human Feces: Prevalence of Plant Pathogenic Viruses [PDF]

, 2005
The human gut is known to be a reservoir of a wide variety of microbes, including viruses. Many RNA viruses are known to be associated with gastroenteritis; however, the enteric RNA viral community present in healthy humans has not been described.
Altschul, Altschul, Andrews, Backhed, Banyai, Breitbart, Breitbart, Castello, Chandra, Chia Lin Wei, Clark, Craggs, Dolin, Dolin, Edison T Liu, Ewing, Ewing, Forest Rohwer, Glass, Gorski, Griffin, Hogenhout, Hwang, Jagadish, Jeffrey Dangl, Jin-Quan Run, Lewandowski, Macpherson, Martin L Hibberd, Middleton, Murray, Mya Breitbart, Nicholson, Noble, Osawa, Pereira, Peyrefitte, Power, Purvis, Rogers, Rohwer, Rosen, Rubinstein, Shirlena Wee Ling Soh, Tao Zhang, Tringe, Tyson, Venter, Wah Heng Lee, Weinbauer, Wetter, Wilhelmi, Xi, Xu, Yijun Ruan, Yusibov   +55 more
core   +5 more sources

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Localization of Electronic States in Chain Model Based on Real DNA Sequence

, 2004
We investigate the localization property of an electron in the disordered two-chain system (ladder model) with long-range correlation as a simple model for electronic property in DNA sequence.
Aizawa, Aizawa, Badi, Berlin, Bruinsma, Buldyrev, Carpena, Carpena, Crisanti, Cuniberti, Damle, de Moura, Di Felice, Grosse, Hennig, Hennig, Hiroaki Yamada, Holste, Holste, Iguchi, Iguchi, Iguchi, Iguchi, Isohata, Kats, Kurita, Ladik, Ladik, LeBard, Lewis, Ohno, Paun, Porath, Porath, Roche, Roche, Rodriguez, Shen, Starikov, Tikhonov, Tran, Troisi, Voss, Yamada, Yamada, Yamada, Yamada, Yamada, Yu   +48 more
core   +2 more sources

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

Complete Genome Sequences of Paenibacillus Larvae Phages BN12, Dragolir, Kiel007, Leyra, Likha, Pagassa, PBL1c, and Tadhana [PDF]

, 2018
We present here the complete genomes of eight phages that infect Paenibacillus larvae, the causative agent of American foulbrood in honeybees. Phage PBL1c was originally isolated in 1984 from a P.
Berg, Jordan A., Breakwell, Donald P., Dhalai, Aziza, Dingman, Douglas W., Fajardo, Chris P., Graves, Kiel, Grose, Julianne H., Hill, Hunter L., Hilton, Jared A., Hope, Sandra, Imahara, Cameron, Knabe, Bradley K., Mangohig, James, Merrill, Bryan D., Monk, Josh, Mun, Heejin, Payne, Ashley M., Salisbury, Alicia, Stamereilers, Casey, Tsourkas, Philippos K., Velez, Kathie, Walker, Jamison K., Ward, Andy T.   +22 more
core   +2 more sources

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Metavirome Sequencing of the Termite Gut Reveals the Presence of an Unexplored Bacteriophage Community

Frontiers in Microbiology, 2018
The Formosan subterranean termite; Coptotermes formosanus is nutritionally dependent on the complex and diverse community of bacteria and protozoa in their gut.
Chinmay V. Tikhe, Claudia Husseneder
doaj   +1 more source

Bacteriophage Lysin CF-301, a Potent Antistaphylococcal Biofilm Agent [PDF]

, 2017
Raymond Schuch, Babar K. Khan, Assaf Raz, Jimmy A. Rotolo, Michael Wittekind   +4 more
openalex   +1 more source

Experimental phage therapy of burn wound infection : difficult first steps [PDF]

, 2014
Antibiotic resistance has become a major public health problem and the antibiotics pipeline is running dry. Bacteriophages (phages) may offer an ‘innovative’ means of infection treatment, which can be combined or alternated with antibiotic therapy and ...
De Vos, Daniel, Jennes, Serge, Lavigne, Rob, Merabishvili, Maia, Pirnay, Jean Paul, Rose, Thomas, Vaneechoutte, Mario, Verbeken, Gilbert, Zizi, Martin   +8 more
core