Results 61 to 70 of about 193,109 (387)
Фундаментальная и клиническая медицина, 2022 Antibiotic resistance represents an urgent and unresolved issue due to a rapid spread of multidrug-resistance organisms (MDROs). An alternative approach is the medical use of bacteriophages which have selective and lytic activity against specific ...
K. M. Bagandova +8 more
doaj +1 more source
The influence of the accessory genome on bacterial pathogen evolution [PDF]
, 2011 Bacterial pathogens exhibit significant variation in their genomic content of virulence factors. This reflects the abundance of strategies pathogens evolved to infect host organisms by suppressing host immunity.
Abu-Ali GS +120 more
core +2 more sources
Ethics framework for treatment use of investigational drugs
BMC Medical Ethics, 2020 Background Expanded access is the use of investigational drugs (IDs) outside of clinical trials. Generally it is performed in patients with serious and life-threatening diseases who cannot be treated satisfactorily with authorized drugs.
Jan Borysowski, Andrzej Górski
doaj +1 more source
Bacteriophages as Alternatives to Antibiotics in Clinical Care
Antibiotics, 2019 Antimicrobial resistance is increasing despite new treatments being employed. With a decrease in the discovery rate of novel antibiotics, this threatens to take humankind back to a “pre-antibiotic era” of clinical care. Bacteriophages (phages) are one of
D. Romero-Calle +3 more
semanticscholar +1 more source
THE GROWTH OF BACTERIOPHAGE [PDF]
Journal of General Physiology, 1939 1. An anti-Escherichia coli phage has been isolated and its behavior studied. 2. A plaque counting method for this phage is described, and shown to give a number of plaques which is proportional to the phage concentration. The number of plaques is shown to be independent of agar concentration, temperature of plate incubation, and ...
Ellis, Emory L., Delbrück, Max
openaire +3 more sources
Microorganisms, 2020 Despite their simplicity, viruses can display social-like interactions such as cooperation, communication, and cheating. Focusing on bacteriophages, here we review features including viral product sharing, cooperative evasion of antiviral defenses, prudent host exploitation, superinfection exclusion, and inter-phage peptide-mediated signaling. We argue
Pilar Domingo-Calap +2 more
openaire +4 more sources
Comparative Genomics of 9 Novel Paenibacillus Larvae Bacteriophages [PDF]
, 2016 American Foulbrood Disease, caused by the bacterium Paenibacillus larvae, is one of the most destructive diseases of the honeybee, Apis mellifera. Our group recently published the sequences of 9 new phages with the ability to infect and lyse P.
Amy, Penny S. +4 more
core +2 more sources
Bacteriophages in Natural and Artificial Environments
Pathogens, 2019 Bacteriophages (phages) are biological entities that have attracted a great deal of attention in recent years. They have been reported as the most abundant biological entities on the planet and their ability to impact the composition of bacterial ...
Steven Batinovic +14 more
semanticscholar +1 more source
Fine Structure of Viral dsDNA Encapsidation [PDF]
, 2019 In vivo configurations of dsDNA of bacteriophage viruses in a capsid are known to form hexagonal chromonic liquid crystal phases. This article studies the liquid crystal ordering of viral dsDNA in an icosahedral capsid, combining the chromonic model with
Arsuaga, Javier +4 more
core +3 more sources
Application of bacteriophages [PDF]
Microbiology Australia, 2017 The emergence of antibiotic-resistant bacteria and decrease in the discovery rate of novel antibiotics takes mankind back to the ‘pre-antibiotic era’ and search for alternative treatments. Bacteriophages have been one of promising alternative agents which can be utilised for medicinal and biological control purposes in agriculture and related fields ...
Aminov, Rustam +14 more
openaire +3 more sources