Results 41 to 50 of about 94,356 (310)

454-Pyrosequencing: A Molecular Battiscope for Freshwater Viral Ecology [PDF]

open access: yes, 2010
Viruses, the most abundant biological entities on the planet, are capable of infecting organisms from all three branches of life, although the majority infect bacteria where the greatest degree of cellular diversity lies.
Ackermann   +13 more
core   +3 more sources

Prolongation of Fate of Bacteriophages In Vivo by Polylactic-Co-Glycolic-Acid/Alginate-Composite Encapsulation

open access: yesAntibiotics, 2022
With concern growing over antibiotics resistance, the use of bacteriophages to combat resistant bacteria has been suggested as an alternative strategy with which to enable the selective control of targeted pathogens.
Sang-Guen Kim   +9 more
doaj   +1 more source

Complete Genome Sequences of vB_LmoS_188 and vB_LmoS_293, Two Bacteriophages with Specificity for Listeria monocytogenes Strains of Serotypes 4b and 4e [PDF]

open access: yes, 2015
peer-reviewedListeria monocytogenes is responsible for the rare disease listeriosis, which is associated with the consumption of contaminated food products. We report here the complete genome sequences of vB_LmoS_188 and vB_LmoS_293, phages isolated from
Casey, A.   +3 more
core   +1 more source

Fine Structure of Viral dsDNA Encapsidation [PDF]

open access: yes, 2019
In vivo configurations of dsDNA of bacteriophage viruses in a capsid are known to form hexagonal chromonic liquid crystal phases. This article studies the liquid crystal ordering of viral dsDNA in an icosahedral capsid, combining the chromonic model with
Arsuaga, Javier   +4 more
core   +3 more sources

Genetically modified bacteriophages creating for the treatment of infections caused by multidrug resistant bacteria (review)

open access: yesФундаментальная и клиническая медицина, 2022
Antibiotic resistance represents an urgent and unresolved issue due to a rapid spread of multidrug-resistance organisms (MDROs). An alternative approach is the medical use of bacteriophages which have selective and lytic activity against specific ...
K. M. Bagandova   +8 more
doaj   +1 more source

Transduction of bacteriophage lambda by bacteriophage T1 [PDF]

open access: yesJournal of Virology, 1979
When bacteriophage T1 was grown on bacteriophage lambda-lysogenic cells, phenotypically mixed particles were formed which had the serum sensitivity, host range, and density of T1 but which gave rise to lambda phage. T1 packaged lambda genomes more efficiently both when the length of the prophage was less than that of wild-type lambda and when the host ...
H, Drexler, J R, Christensen
openaire   +2 more sources

Ethics framework for treatment use of investigational drugs

open access: yesBMC Medical Ethics, 2020
Background Expanded access is the use of investigational drugs (IDs) outside of clinical trials. Generally it is performed in patients with serious and life-threatening diseases who cannot be treated satisfactorily with authorized drugs.
Jan Borysowski, Andrzej Górski
doaj   +1 more source

Isolation, characterisation and experimental evolution of phage that infect the horse chestnut tree pathogen, Pseudomonas syringae pv. aesculi [PDF]

open access: yes, 2020
Bleeding canker of horse chestnut trees is a bacterial disease, caused by the bacterium Pseudomonas syringae pv. aesculi, estimated to be present in ~ 50% of UK horse chestnut trees.
Jackson, Robert W.   +4 more
core   +3 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]

open access: yes, 2017
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core   +1 more source

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