Results 41 to 50 of about 74,690 (303)

Bacteriophage Assembly [PDF]

open access: yesViruses, 2011
Bacteriophages have been a model system to study assembly processes for over half a century. Formation of infectious phage particles involves specific protein-protein and protein-nucleic acid interactions, as well as large conformational changes of assembly precursors.
Aksyuk, Anastasia A.   +1 more
openaire   +3 more sources

Screening of Anorectal and Oropharyngeal Samples Fails to Detect Bacteriophages Infecting Neisseria gonorrhoeae

open access: yes, 2022
There are real concerns that Neisseria gonorrhoeae may become untreatable in the near future due to the rapid emergence of antimicrobial resistance. Alternative therapies are thus urgently required. Bacteriophages active against N. gonorrhoeae could play
Tessa de Block   +23 more
core   +1 more source

Genetically modified bacteriophages creating for the treatment of infections caused by multidrug resistant bacteria (review)

open access: yesФундаментальная и клиническая медицина, 2022
Antibiotic resistance represents an urgent and unresolved issue due to a rapid spread of multidrug-resistance organisms (MDROs). An alternative approach is the medical use of bacteriophages which have selective and lytic activity against specific ...
K. M. Bagandova   +8 more
doaj   +1 more source

Application of bacteriophages on Shiga toxin-producing Escherichia coli (STEC) biofilm [PDF]

open access: yes, 2021
Shiga toxin-producing Escherichia coli are pathogenic bacteria able to form biofilms both on abiotic surfaces and on food, thus increasing risks for food consumers.
Roberto Foschino   +2 more
core   +1 more source

Growing Trend of Fighting Infections in Aquaculture Environment—Opportunities and Challenges of Phage Therapy

open access: yes, 2020
Phage therapy, a promising alternative to antimicrobial treatment of bacterial diseases, is getting more and more popular, especially due to the rising awareness of antibiotic resistance and restrictions in antibiotics’ use. During recent years, we
Jarosław Dastych   +5 more
core   +1 more source

Bacteriophages [PDF]

open access: yes, 2012
Bacteriophages have received attention as biological control agents since their discovery and recently their value as tools has been further emphasized in many different fields of microbiology. Particularly, in drug design and development programs, phage

core   +2 more sources

Ethics framework for treatment use of investigational drugs

open access: yesBMC Medical Ethics, 2020
Background Expanded access is the use of investigational drugs (IDs) outside of clinical trials. Generally it is performed in patients with serious and life-threatening diseases who cannot be treated satisfactorily with authorized drugs.
Jan Borysowski, Andrzej Górski
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Bacteriophages and the One Health Approach to Combat Multidrug Resistance: Is This the Way?

open access: yes, 2020
Antimicrobial resistance necessitates action to reduce and eliminate infectious disease, ensure animal and human health, and combat emerging diseases.
Mary Garvey
core   +1 more source

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