Results 81 to 90 of about 133,663 (234)

Bacteriocins and Bacteriophages: Therapeutic Weapons for Gastrointestinal Diseases?

open access: yesInternational Journal of Molecular Sciences, 2019
Bacteriocins are bactericidal peptides, ribosomally synthesized, with an inhibitory activity against diverse groups of undesirable microorganisms. Bacteriocins are produced by both gram-positive and gram-negative bacteria, and to a lesser extent by some ...
L. Lopetuso   +5 more
semanticscholar   +1 more source

Direct Electron Microscopy Study on the Morphological Diversity of Bacteriophage Populations in Lake Plußsee [PDF]

open access: yes, 1993
Direct electron microscopy of bacteriophages adsorbed to a carbon film without prior enrichment by specific host strains or concentration by physical or chemical methods was used to study the morphological diversity of natural bacteriophage assemblages ...
Demuth, Jutta   +2 more
core   +1 more source

Phage therapy : its uses and flaws pertaining to pseudomonas aeruginosa infections [PDF]

open access: yes, 2020
As cases of antibiotic resistant bacteria increase, possible alternatives to antibiotics have often been sought. One alternative discussed in literature is phage therapy.
Vella, Miguel
core  

Bacteriophage-resistant and bacteriophage-sensitive bacteria in a chemostat [PDF]

open access: yesMathematical Biosciences and Engineering, 2012
In this paper a mathematical model of the population dynamics of a bacteriophage-sensitive and a bacteriophage-resistant bacteria in a chemostat where the resistant bacteria is an inferior competitor for nutrient is studied. The focus of the study is on persistence and extinction of bacterial strains and bacteriophage.
Zhun Han, Hal L. Smith
openaire   +3 more sources

Bacteriophages as Adjuvant to Antibiotics for the Treatment of Periprosthetic Joint Infection Caused by Multidrug-Resistant Pseudomonas aeruginosa

open access: yesAntimicrobial Agents and Chemotherapy, 2019
We documented the adjunctive bacteriophage therapy to treat a chronic relapsing periprosthetic joint infection of the knee and chronic osteomyelitis of the femur caused by multidrug-resistant Pseudomonas aeruginosa.
T. Tkhilaishvili   +4 more
semanticscholar   +1 more source

The influence of the accessory genome on bacterial pathogen evolution [PDF]

open access: yes, 2011
Bacterial pathogens exhibit significant variation in their genomic content of virulence factors. This reflects the abundance of strategies pathogens evolved to infect host organisms by suppressing host immunity.
Abu-Ali GS   +120 more
core   +2 more sources

Nonuniform Donnan Equilibrium within Bacteriophages Packed with Dna [PDF]

open access: yesarXiv, 2003
The curvature stress of DNA packed inside a phage is balanced against its electrostatic self-interaction. The DNA density is supposed nonuniform and as a result the Donnan effect is also inhomogeneous. The coarse-grained DNA density is a nonlinear function of the DNA radius of curvature at a given position inside the bacteriophage.
arxiv  

Improved lyophilization conditions for long-term storage of bacteriophages

open access: yesScientific Reports, 2019
Phage therapy is one of the promising alternatives to combat the increasing problem of antibiotic resistance. Lyophilization is used for the preparation of pharmaceutical products to improve their stability in long-term storage. The aim of this study was
P. Manohar, N. Ramesh
semanticscholar   +1 more source

DNA looping provides stability and robustness to the bacteriophage lambda switch [PDF]

open access: yes, 2009
The bistable gene regulatory switch controlling the transition from lysogeny to lysis in bacteriophage lambda presents a unique challenge to quantitative modeling. Despite extensive characterization of this regulatory network, the origin of the extreme stability of the lysogenic state remains unclear.
arxiv   +1 more source

Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?

open access: yesOpen Forum Infectious Diseases, 2018
Local injection of a bacteriophages mix during debridement, antibiotics and implant retention (“DAIR”) was performed to treat a relapsing Staphylococcus aureus chronic prosthetic joint infection (PJI).
T. Ferry   +69 more
semanticscholar   +1 more source

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