Life in the brine of Lunenburg, Germany: unveiling microorganisms associated with Zechstein salt deposits [PDF]
IntroductionThe presence of hypersaline brines on other planets and moons in the inner and outer Solar System has been well established. Hence, any theory of life on other planets must consider microorganisms adapted to high salt concentrations.
Katharina Runzheimer +8 more
doaj +2 more sources
Engineering Haloferax mediterranei as an Efficient Platform for High Level Production of Lycopene [PDF]
Lycopene attracts increasing interests in the pharmaceutical, food, and cosmetic industries due to its anti-oxidative and anti-cancer properties. Compared with other lycopene production methods, such as chemical synthesis or direct extraction from plants,
Zhen-Qiang Zuo +9 more
doaj +3 more sources
Haloferax mediterranei R4 for bioremediation of desalination and textile wastes: a step towards their valorisation [PDF]
Haloferax mediterranei has shown strong potential for bioremediating brines contaminated with nitrogenous compounds, oxychlorides, and metals, making it a promising candidate for treating saline wastewater.
Iraide Sáez-Zamacona +2 more
doaj +2 more sources
Antioxidative and chaperone-like activities of a bacterioruberin-rich extract: An innovative approach to protect the skin proteome. [PDF]
The bacteriorubin‐rich extract of Arthrobacter agilis has high antioxidative properties, protecting proteins against oxidative stress and preventing their carbonylation. It also protects proteins against saline and heat stresses, suggesting a dual mode of action including antioxidant and chaperone‐like activities.
Tisserand JC +7 more
europepmc +2 more sources
The Antitumour Mechanisms of Carotenoids: A Comprehensive Review [PDF]
Carotenoids, known for their antioxidant properties, have garnered significant attention for their potential antitumour activities. This comprehensive review aims to elucidate the diverse mechanisms by which carotenoids exert antitumour effects, focusing
Andrés Baeza-Morales +7 more
doaj +2 more sources
Elucidating metabolic pathways through genomic analysis in highly heavy metal-resistant Halobacterium salinarum strains. [PDF]
The annotated and predicted genomes of five archaeal strains (AS1, AS2, AS8, AS11 and AS19), isolated from Sfax solar saltern sediments (Tunisia) and affiliated with Halobacterium salinarum, were performed by RAST webserver (Rapid Annotation using ...
Baati H +6 more
europepmc +3 more sources
Nebulized Bacterioruberin/Astaxanthin-Loaded Nanovesicles: Antitumoral Activity and Beyond. [PDF]
The membranes of halophilic archaea are a source of novel biomaterials, mainly of isoprenoid nature, with therapeutic properties practically unraveled. Here, we explored the antitumoral activity of neutral archaeolipids (NAs, such as bacterioruberin, astaxanthin, and dihydrosqualene) present in the total archaeolipids (TAs) (a fraction from the first ...
González Epelboim VRD +10 more
europepmc +3 more sources
Microbial Bacterioruberin: A Comprehensive Review. [PDF]
Bacterioruberin (BR) is a fat-soluble, dipolar, reddish pigment predominantly found in halophilic archaea. BR is a rare C50 carotenoid from the xanthophyll family, and it has been extensively studied for its potent antioxidant properties, such as its ability to protect cells from oxidative stress.
Palanisamy M, Ramalingam S.
europepmc +3 more sources
Biological properties of carotenoids extracted from Halobacterium halobium isolated from a Tunisian solar saltern [PDF]
Background: Bioactive molecules have received increasing attention due to their nutraceutical attributes and anticancer, antioxidant, antiproliferative and apoptosis-inducing properties.
Abbes, M +6 more
core +3 more sources
Large proteins support remarkably high charge transport rates, but the factors that influence the charge transport mechanism are still unclear. This work shows the importance of structural order: ordered structures support coherent tunnelling pathways while charges “hop” across disordered structures.
Nipun Kumar Gupta +8 more
wiley +1 more source

