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Identifying Keystone Species in the Human Gut Microbiome from Metagenomic Timeseries using Sparse Linear Regression [PDF]

open access: yes, 2014
Human associated microbial communities exert tremendous influence over human health and disease. With modern metagenomic sequencing methods it is possible to follow the relative abundance of microbes in a community over time.
Fisher, Charles K., Mehta, Pankaj
core   +14 more sources

Multi-omics analyses of the Ulcerative Colitis gut microbiome link Bacteroides vulgatus proteases with disease severity

open access: yesNature Microbiology, 2021
Ulcerative colitis (UC) is driven by disruptions in host–microbiota homoeostasis, but current treatments exclusively target host inflammatory pathways. To understand how host–microbiota interactions become disrupted in UC, we collected and analysed six ...
R. Mills   +22 more
semanticscholar   +1 more source

The composition of the gut microbiome in patients with sarcopenia

open access: yesTürk Biyokimya Dergisi, 2022
The purpose of this study is to predict sarcopenia by analyzing the composition of the gut microbiota.
Wu Yue   +6 more
doaj   +1 more source

Week-Old Chicks with High Bacteroides Abundance Have Increased Short-Chain Fatty Acids and Reduced Markers of Gut Inflammation

open access: yesMicrobiology spectrum, 2023
To date, limited information is available comparing distinct Bacteroides compositions in the chicken gut microbial communities, particularly in the context of microbial functional capacities and host responses.
Yi-Heng Fan   +4 more
semanticscholar   +1 more source

Nutrient niche specificity for glycosaminoglycans is reflected in polysaccharide utilization locus architecture of gut Bacteroides species

open access: yesFrontiers in Microbiology, 2022
IntroductionGlycosaminoglycans (GAGs) present in the mucosal layer can be used as nutrients by certain intestinal bacteria, particularly members of the Bacteroides.
Annelieke Overbeeke   +8 more
doaj   +1 more source

Salmonella-induced changes in the level of key immunoregulatory bacteria affect the transcriptional activity of the Foxp3 and RORgt genes in the gut-associated lymphoid tissue of rats

open access: yesИнфекция и иммунитет, 2020
Intestinal microbes involved in many physiological processes owner, contributes to the formation and maintenance of immune homeostasis by regulating immune responses to protect against colonization by pathogens.
Yu. V. Bukina   +6 more
doaj   +1 more source

Bacteroides acidifaciens in the gut plays a protective role against CD95-mediated liver injury

open access: yesGut microbes, 2022
The intestinal flora plays an important role in the development of many human and animal diseases. Microbiome association studies revealed the potential regulatory function of intestinal bacteria in many liver diseases, such as autoimmune hepatitis ...
Hesuiyuan Wang   +18 more
semanticscholar   +1 more source

Cesarean section induced dysbiosis promotes type 2 immunity but not oxazolone-induced dermatitis in mice

open access: yesGut Microbes, 2023
Delivery by cesarean section (CS) is associated with an altered gut microbiota (GM) colonization and a higher risk of later chronic inflammatory diseases.
Line Fisker Zachariassen   +7 more
doaj   +1 more source

Classification of Parabacteroides distasonis and other Bacteroidetes using O- antigen virulence gene: RfbA-Typing and hypothesis for pathogenic vs. probiotic strain differentiation

open access: yesGut Microbes, 2022
Parabacteroides distasonis (Pdis) is the type species for the new Parabacteroides genus, and a gut commensal of the Bacteroidetes phylum. Emerging reports (primarily based on reference strain/ATCC-8503) concerningly propose that long-known opportunistic ...
Nicholas C. Bank   +2 more
doaj   +1 more source

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