"Capnocytophaga canimorsus" : discovery of a deglycosylation mechanism that links metabolism to pathogenesis [PDF]
We show that C. canimorsus (Cc) can serve as a recipient for RP4 mediated conjugation but there is neither replication of broad host range plasmid vectors nor expression of commonly used E. coli markers in C. canimorsus.
Mally, Manuela
core +1 more source
Bacteriodes fragilis interactions with the collagen type I component of the host extracellular matrix [PDF]
Includes bibliographical references (p. 116-126).Bacteroides fragilis is an opportunistic pathogen which can cause life threatening infections in humans and animals.
Galvao, Bruna Patricia Gomes de Vasconcelos
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Bacteroides spp. and diarrhea [PDF]
The purpose of this review is to describe recent progress in the understanding of the role of Bacteroides spp. in human diarrheal diseases and newer murine studies implicating certain Bacteroides spp. in colorectal cancer.Bacteroides fragilis is the only strain of Bacteroides spp. associated with diarrheal disease.
Elizabeth C, Wick, Cynthia L, Sears
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Gut Bacteroides act in a microbial consortium to cause susceptibility to severe malaria
Malaria is caused by Plasmodium species and remains a significant cause of morbidity and mortality globally. Gut bacteria can influence the severity of malaria, but the contribution of specific bacteria to the risk of severe malaria is unknown.
Rabindra K. Mandal +5 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Nachweis von enterotoxigenen Bacteroides fragilis Stämmen aus klinischen Materialien und molekulare Charakterisierung der Bacteroides fragilis Pathogenitätsinsel [PDF]
B. fragilis wird mit klinischen Bildern mit wie Abdominal- und Weichgewebs-Infektionen sowie Sepsis-Geschehen assoziiert, weitere Krankheitsbilder sind noch in der Erforschung.
Claros, Zaida
core +1 more source
Objective To compare the differences in gut microbiota between cirrhosis patients receiving transjugular intrahepatic portosystemic shunt (TIPS) and those not, and explore the relationship between TIPS surgery and gut microbiota in order to provide new ...
LI Shengpeng, XIAO Xu, ZHOU An
doaj +1 more source

