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Advances in the Arms Race Between Silkworm and Baculovirus
Insects are the largest group of animals. Nearly all organisms, including insects, have viral pathogens. An important domesticated economic insect is the silkworm moth Bombyx mori. B.
Liang Jiang +4 more
doaj +2 more sources
Baculoviruses are insect-specific DNA viruses that have been exploited as bioinsecticides for the control of agricultural and forest pests around the world.
María Leticia Ferrelli +1 more
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An Advanced View on Baculovirus per Os Infectivity Factors [PDF]
Baculoviruses are arthropod-specific large DNA viruses that orally infect the larvae of lepidopteran, hymenopteran and dipteran insect species. These larvae become infected when they eat a food source that is contaminated with viral occlusion bodies (OBs)
B. Boogaard +2 more
semanticscholar +2 more sources
Baculovirus as a Tool for Gene Delivery and Gene Therapy
Based on its ability to express high levels of protein, baculovirus has been widely used for recombinant protein production in insect cells for more than thirty years with continued technical improvements.
Chikako Ono +3 more
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Comparative Evaluation of Human Papillomavirus Type 16 L1 Protein Expressed in Plasmid- and Baculovirus-Based Systems in Insect Cells [PDF]
Human papillomavirus (HPV) has been associated with specific types of papillomas, lesions at particular anatomic sites, and malignancies. The HPV16 and HPV18 have been shown to play a role in a variety of carcinomas.
B. Abedi Kiasari
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Inhibition of melanization by serpin-5 and serpin-9 promotes baculovirus infection in cotton bollworm Helicoverpa armigera. [PDF]
Melanization, an important insect defense mechanism, is mediated by clip-domain serine protease (cSP) cascades and is regulated by serpins. Here we show that proteolytic activation of prophenoloxidase (PPO) and PO-catalyzed melanization kill the ...
Chuanfei Yuan +7 more
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Although the modulation of host physiology has been interpreted as an essential process supporting baculovirus propagation, the requirement of energy supply for host antivirus reactions could not be ruled out.
Yu-Hsien Lin +8 more
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Purification of baculovirus vectors using heparin affinity chromatography
Baculoviruses are commonly used for recombinant protein and vaccine production. Baculoviruses are nonpathogenic to vertebrates, have a large packaging capacity, display broad host and cell type tropism, infect both dividing and nondividing cells, and do ...
Md Nasimuzzaman +3 more
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Iflavirus increases its infectivity and physical stability in association with baculovirus [PDF]
Virus transmission and the prevalence of infection depend on multiple factors, including the interaction with other viral pathogens infecting the same host.
Agata K. Jakubowska +6 more
doaj +3 more sources
Genetic engineering of baculovirus-insect cell system to improve protein production
The Baculovirus Expression Vector System (BEVS), a mature foreign protein expression platform, has been available for decades, and has been effectively used in vaccine production, gene therapy, and a host of other applications.
M. Hong +10 more
semanticscholar +1 more source

