Results 1 to 10 of about 73,636 (212)

LEF-6 phosphorylation regulates the binding and trafficking of baculovirus late gene transcripts [PDF]

open access: yesJournal of Virology
The Autographa californica multiple nucleopolyhedrovirus (AcMNPV) LEF-6 has been shown to accelerate the infection cycle of AcMNPV, but its specific function is yet to be defined.
Xiaoyue Zhang   +5 more
doaj   +2 more sources

A Baculovirus Expression Vector Derived Entirely from Non-Templated, Chemically Synthesized DNA Parts

open access: yesViruses, 2023
Baculovirus expression system1s are a widely used tool in recombinant protein and biologics production. To enable the possibility of genome modifications unconstrained through low-throughput and bespoke classical genome manipulation techniques, we set ...
Christopher Nguyen   +2 more
doaj   +1 more source

Clathrin-independent entry of baculovirus triggers uptake of E. coli in non-phagocytic human cells. [PDF]

open access: yesPLoS ONE, 2009
The prototype baculovirus, Autographa californica multiple nucleopolyhedrovirus, an insect pathogen, holds great potential as a gene therapy vector. To develop transductional targeting and gene delivery by baculovirus, we focused on characterizing the ...
Johanna P Laakkonen   +10 more
doaj   +1 more source

Advances in the Arms Race Between Silkworm and Baculovirus

open access: yesFrontiers in Immunology, 2021
Insects are the largest group of animals. Nearly all organisms, including insects, have viral pathogens. An important domesticated economic insect is the silkworm moth Bombyx mori. B.
Liang Jiang   +4 more
doaj   +1 more source

Significant productivity improvement of the baculovirus expression vector system by engineering a novel expression cassette. [PDF]

open access: yesPLoS ONE, 2014
Here we describe the development of a baculovirus vector expression cassette containing rearranged baculovirus-derived genetic regulatory elements. This newly designed expression cassette conferred significant production improvements to the baculovirus ...
Silvia Gómez-Sebastián   +2 more
doaj   +1 more source

Therapy of cancer by insect cells containing recombinant baculovirus encoding genes [PDF]

open access: yes, 2002
Provided are compositions and methods of use for insect cells comprising baculovirus encoding non-surface expressed proteins and peptides. The claimed invention particularly relates to compositions comprising insect cells containing baculovirus that ...
Dhong, Zhongyun   +2 more
core   +1 more source

Genome-wide diversity in temporal and regional populations of the betabaculovirus Erinnyis ello granulovirus (ErelGV)

open access: yesBMC Genomics, 2018
Background Erinnyis ello granulovirus (ErelGV) is a betabaculovirus infecting caterpillars of the sphingid moth E. ello ello (cassava hornworm), an important pest of cassava crops (Manihot esculenta).
A. F. Brito   +5 more
doaj   +1 more source

Studies on processing, particle formation, and immunogenicity of the HIV-1 gag gene product: a possible component of a HIV vaccine [PDF]

open access: yes, 1992
Antigens in a particulate conformation were shown to be highly immunogenic in mammals. For this reason, the particle forming capacity of derivatives of the HIV-1 group specific core antigen p55 gag was assayed and compared dependent on various expression
Deby, G.   +7 more
core   +1 more source

Genetics instability of wtAAV2 genome and AAV promoter activities in the Baculovirus/Sf9 cells system.

open access: yesPLoS ONE, 2018
The human Adeno-Associated Virus serotype 2 (wtAAV2) is a common non-pathological virus and its recombinant form (rAAV) is widely used as gene therapy vector. Although rAAVs are routinely produced in the Baculovirus/Sf9 cell system, wtAAV2 has never been
Adrien Savy   +5 more
doaj   +1 more source

Quantitative proteomics of Spodoptera frugiperda cells during growth and baculovirus infection. [PDF]

open access: yesPLoS ONE, 2011
Baculovirus infection of Spodoptera frugiperda cells is a system of choice to produce a range of recombinant proteins, vaccines and, potentially, gene therapy vectors. While baculovirus genomes are well characterized, the genome of S.
Nuno Carinhas   +6 more
doaj   +1 more source

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