Results 91 to 100 of about 99,639 (312)
Increase in gut microbiota after immune suppression in baculovirus-infected larvae.
PLoS Pathogens, 2013 Spodoptera exigua microarray was used to determine genes differentially expressed in S. exigua cells challenged with the species-specific baculovirus SeMNPV as well as with a generalist baculovirus, AcMNPV.
Agata K Jakubowska +2 more
doaj +1 more source
Highly efficient baculovirus-mediated multigene delivery in primary cells
Nature Communications, 2016 Multigene delivery and subsequent cellular expression is emerging as a key technology required in diverse research fields including, synthetic and structural biology, cellular reprogramming and functional pharmaceutical screening.
M. Mansouri +13 more
semanticscholar +1 more source
A practical method for efficient and optimal production of Seleno‐methionine‐labeled recombinant protein complexes in the insect cells [PDF]
, 2019 The use of Seleno‐methionine (SeMet) incorporated protein crystals for single or multi‐wavelength anomalous diffraction (SAD or MAD) to facilitate phasing has become almost synonymous with modern X‐ray crystallography.
Imasaki, Tsuyoshi +2 more
core +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito +6 more
wiley +1 more source
BioTechniques, 2004 Recombinant baculoviruses derived from the Autographa californica nuclear polyhedrosis virus (AcNPV) are widely used to express heterologous genes in insect cells, but the use of the baculovirus expression vector system (BEVS) is hampered by slow and ...
Björn Philipps +2 more
doaj +1 more source
Cancer Science, EarlyView.Upon chemotherapy, a subset of cancer cells enters a senescent state, referred to as TIS. When IAP antagonists are administered, TIS cells are selectively eliminated through TNFα‐independent apoptosis. TNFα secreted by TIS cancer cells may also act in a paracrine manner to enhance extrinsic apoptosis in neighboring non‐senescent cancer cells.
Hiroaki Ochiiwa +7 more
wiley +1 more source
Genome Scale Transcriptomics of Baculovirus-Insect Interactions
Viruses, 2013 Baculovirus-insect cell technologies are applied in the production of complex proteins, veterinary and human vaccines, gene delivery vectors‚ and biopesticides.
Steven Reid +2 more
doaj +1 more source
Baculovirus Per Os Infectivity Factors Form a Complex on the Surface of Occlusion-Derived Virus [PDF]
, 2010 Five highly conserved per os infectivity factors, PIF1, PIF2, PIF3, PIF4, and P74, have been reported to be essential for oral infectivity of baculovirus occlusion-derived virus (ODV) in insect larvae.
Hu, Z. +4 more
core +2 more sources
Intrinsic specificity of a ‘core’ TIP60 acetyltransferase complex in Drosophila
The FEBS Journal, EarlyView.The intrinsic substrate selectivity of the Drosophila TIP60‐core acetyltransferase was determined using synthetic nucleosome arrays. Targeted mass spectrometry revealed site‐specific acetylation of histones H2A, H2A.V, and H4, uncovering distinct acetylation rates and patterns across individual lysines.
Silke Krause +5 more
wiley +1 more source
Manufacturing of AcMNPV baculovirus vectors to enable gene therapy trials
Molecular Therapy: Methods & Clinical Development, 2016 Over the past two decades, baculoviruses have become workhorse research tools for transient transgene expression. Although they have not yet been used directly as a gene therapy vector in the clinical setting, numerous preclinical studies have suggested ...
T. Kwang, Xinhui Zeng, Shu Wang
semanticscholar +1 more source