Results 71 to 80 of about 93,476 (270)

Studies on processing, particle formation, and immunogenicity of the HIV-1 gag gene product: a possible component of a HIV vaccine [PDF]

, 1992
Antigens in a particulate conformation were shown to be highly immunogenic in mammals. For this reason, the particle forming capacity of derivatives of the HIV-1 group specific core antigen p55 gag was assayed and compared dependent on various expression
Deby, G., Fliessbach, H., Motz, M., Niedrig, M., von Brunn, A., Wagner, R., Wanner, G., Wolf, Hans J.   +7 more
core   +1 more source

Baculovirus-driven protein expression in insect cells: A benchmarking study.

Journal of Structural Biology, 2018
Baculovirus-insect cell expression system has become one of the most widely used eukaryotic expression systems for heterologous protein production in many laboratories.
Peggy Stolt-Bergner, C. Benda, Tim Bergbrede, H. Besir, P. Celie, Cindy Chang, D. Drechsel, A. Fischer, A. Geerlof, B. Giabbai, J. van den Heuvel, G. Huber, W. Knecht, Anita Lehner, Régis P. Lemaitre, K. Nordén, G. Pardee, I. Racke, K. Remans, A. Sander, Judith D. Scholz, M. Stadnik, P. Storici, Daniel Weinbruch, I. Zaror, L. Lua, S. Suppmann   +26 more
semanticscholar   +1 more source

Replication of baculovirus DNA

Journal of General Virology, 1995
Introduction. The Baculoviridae is a diverse family of pathogens that are infectious for arthropods and are characterized by a complex replication cycle that culminates in the occlusion of virions in a crystalline protein matrix (Blissard & Rohrmann, 1990).
Kool, M., Ahrens, C.H., Vlak, J.M., Rohrmann, G.F.   +3 more
openaire   +3 more sources

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

Developmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu, Katja R. MacCharles, Kenneth Kin Lam Wong, Joy M. Richman, Esther M. Verheyen   +4 more
wiley   +1 more source

Respuesta de IFN-ɤ e IL-4 en ratones inoculados con una proteína G recombinante del virus de la rabia

Revista Mexicana de Ciencias Pecuarias, 2015
El objetivo de este estudio fue comparar el comportamiento de El objetivo de este estudio fue comparar el comportamiento de El objetivo de este estudio fue comparar el comportamiento de IFN-ɤ e IL-4 en ratones inoculados con proteína G recombinante del ...
Edith Rojas-Anaya, Fernando Esquivel-Guadarrama, Estela Escribano-Romero, Ana Belén Blázquez, Graciela Tapia Pérez, Lilia Lilia Soto Ruíz, Elizabeth Loza-Rubio   +6 more
doaj   +1 more source

Comparison of the Interactions of Transferrin Receptor and Transferrin Receptor 2 with Transferrin and the Hereditary Hemochromatosis Protein HFE [PDF]

, 2000
The transferrin receptor (TfR) interacts with two proteins important for iron metabolism, transferrin (Tf) and HFE, the protein mutated in hereditary hemochromatosis.
Andrews, Nancy C., Bennett, Melanie J., Bjorkman, Pamela J., Enns, Caroline A., Sellers, Vera M., West, Anthony P., Jr.   +5 more
core   +1 more source

Construction of a Baculovirus vector containing A subunit of Shiga toxin for protein delivery

Iranian Journal of Microbiology, 2013
Background and Objectives: Baculovirus can be used as a vector in gene delivery system. Viral envelope of baculovirus would display expressed protein/peptide and it could render as a potential vaccine delivery system.
Mana Oloomi, Saeid Bouzari, Maryam Imani, Narges Akhtarian   +3 more
doaj  

WSSV ie1 promoter is more efficient than CMV promoter to express H5 hemagglutinin from influenza virus in baculovirus as a chicken vaccine

BMC Microbiology, 2008
Background The worldwide outbreak of influenza A (H5N1) viruses among poultry species and humans highlighted the need to develop efficacious and safe vaccines based on efficient and scaleable production. Results White spot syndrome virus (WSSV) immediate-
Yu Li, Ho YuenFern, He Fang, Kwang Jimmy
doaj   +1 more source

Evaluation of an inducible knockout system in insect cells based on co-infection and CRISPR/Cas9.

PLoS ONE, 2023
Due to comparably high product titers and low production costs, the baculovirus/insect cell expression system is considered a versatile production platform in the biopharmaceutical industry.
Christina Sophie Hausjell, Miriam Klausberger, Wolfgang Ernst, Reingard Grabherr   +3 more
doaj   +1 more source

Highly efficient baculovirus-mediated multigene delivery in primary cells

Nature Communications, 2016
Multigene delivery and subsequent cellular expression is emerging as a key technology required in diverse research fields including, synthetic and structural biology, cellular reprogramming and functional pharmaceutical screening.
M. Mansouri, Itxaso Bellón-Echeverría, Aurélien Rizk, Zahra Ehsaei, C. Cosentino, Catarina S. Silva, Ye Xie, F. Boyce, M. Davis, S. Neuhauss, V. Taylor, K. Ballmer-Hofer, I. Berger, I. Berger, Philipp Berger   +14 more
semanticscholar   +1 more source