Results 51 to 60 of about 93,476 (270)
Controlled and customizable baculovirus NOS3 gene delivery using PVA-based hydrogel systems.
PLoS ONE, 2023 Nitric oxide synthase 3 (NOS3) eluting polyvinyl alcohol-based hydrogels have a large potential in medical applications and device coatings. NOS3 promotes nitric oxide and nitrate production and can effectively be delivered using insect cell viruses ...
Sabrina Schaly +7 more
doaj +1 more source
Monobac System–A Single Baculovirus for the Production of rAAV
Microorganisms, 2021 Large-scale manufacturing of rAAV is a bottleneck for the development of genetic disease treatments. The baculovirus/Sf9 cell system underpins the first rAAV treatment approved by EMA and remains one of the most advanced platforms for rAAV manufacturing.
Lionel Galibert +10 more
doaj +1 more source
Therapy of cancer by insect cells containing recombinant baculovirus encoding genes [PDF]
, 2002 Provided are compositions and methods of use for insect cells comprising baculovirus encoding non-surface expressed proteins and peptides. The claimed invention particularly relates to compositions comprising insect cells containing baculovirus that ...
Dhong, Zhongyun +2 more
core +1 more source
Journal of General Virology, 2018 Kimura two-parameter nucleotide distance comparisons based on polyhedrin/granulin (polh/gran), late expression factor 8 (lef-8) and late expression factor 9 (lef-9) are a widely applied method for species demarcation for lepidopteran-specific ...
J. Wennmann, J. Keilwagen, J. Jehle
semanticscholar +1 more source
Comprehensive Comparison of Baculoviral and Plasmid Gene Delivery in Mammalian Cells
Viruses(1) Recombinant protein production in mammalian cells is either based on transient transfection processes, often inefficient and underlying high batch-to-batch variability, or on laborious generation of stable cell lines.
Maria Toth +5 more
doaj +1 more source
Nature CommunicationsBaculovirus is an obligate parasitic virus of the phylum Arthropoda. Baculovirus including Autographa californica multiple nucleopolyhedrovirus (AcMNPV) has been widely used in the laboratory and industrial preparation of proteins or protein complexes ...
Yuege Huang +7 more
doaj +1 more source
AMB Express, 2018 Baculovirus is a promising vaccine deliver vector due to its biosafety profiles, gene transfer efficiency, ability to display small foreign antigens on its surface, strong adjuvant activities, etc.
Irisa Trianti +4 more
doaj +1 more source
The Complete Genome Sequence of Plodia Interpunctella Granulovirus: Evidence for Horizontal Gene Transfer and Discovery of an Unusual Inhibitor-of-Apoptosis Gene. [PDF]
PLoS ONE, 2016 The Indianmeal moth, Plodia interpunctella (Lepidoptera: Pyralidae), is a common pest of stored goods with a worldwide distribution. The complete genome sequence for a larval pathogen of this moth, the baculovirus Plodia interpunctella granulovirus (PiGV)
Robert L Harrison +2 more
doaj +1 more source
Family-specific degenerate primer design: a tool to design consensus degenerated oligonucleotides [PDF]
, 2013 Designing degenerate PCR primers for templates of unknown nucleotide sequence may be a very difficult task. In this paper, we present a new method to design degenerate primers, implemented in family-specific degenerate primer design (FAS-DPD) computer ...
Borio, Cristina Silvia +5 more
core +3 more sources
A Mechanistic Model of rAAV Production in Synthetic Cell Lines
Biotechnology and Bioengineering, EarlyView.ABSTRACT The recombinant adeno‐associated virus (rAAV) is a widely used vector for gene therapy. Its manufacturing faces significant challenges in producing the large quantities of vectors needed for clinical applications and reducing empty particles.
Prahalad Srinivasan +5 more
wiley +1 more source