Results 41 to 50 of about 99,639 (312)

Baculovirus vector-mediated transfer of sodium iodide symporter and plasminogen kringle 5 genes for tumor radioiodide therapy. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Both tumor cells and their supporting endothelial cells should be considered for targeted cell killing when designing cancer treatments.
Min Zhang   +5 more
doaj   +1 more source

Monodon Baculovirus of Shrimp [PDF]

open access: yesIndian Journal of Virology, 2012
Among the viruses infecting penaeid shrimp, monodon-type baculovirus (MBV) otherwise known as Penaeus monodon singly enveloped nuclear polyhedrosis virus (PmSNPV), is one of the widely reported and well described viruses. It is a rod-shaped, enveloped, double-stranded DNA virus, and considered till recently, as the type A baculovirus.
K V, Rajendran   +2 more
openaire   +2 more sources

The Drosophila DIAP1 protein is required to prevent accumulation of a continuously generated, processed form of the apical caspase DRONC [PDF]

open access: yes, 2002
Although loss of the inhibitor of apoptosis (LAP) protein DIAP1 has been shown to result in caspase activation and spontaneous cell death in Drosophila cells and embryos, the point at which DIAP1 normally functions to inhibit caspase activation is ...
Clem, Rollie J.   +2 more
core   +1 more source

FlexiBAC: a versatile, open-source baculovirus vector system for protein expression, secretion, and proteolytic processing

open access: yesbioRxiv, 2018
BackgroundBaculovirus-mediated expression in insect cells is a powerful approach for protein production. However, many existing methods are time-consuming, offer limited options for protein tagging, and are unsuitable for secreted proteins requiring ...
Régis P. Lemaitre   +4 more
semanticscholar   +1 more source

The Nuclease Activity of the Yeast Dna2 Protein, Which Is Related to the RecB-like Nucleases, Is Essential in Vivo [PDF]

open access: yes, 2000
Saccharomyces cerevisiae Dna2 protein is required for DNA replication and repair and is associated with multiple biochemical activities: DNA-dependent ATPase, DNA helicase, and DNA nuclease.
Budd, Martin E.   +2 more
core   +1 more source

Development of a Combined Genetic Engineering Vaccine for Porcine Circovirus Type 2 and Mycoplasma Hyopneumoniae by a Baculovirus Expression System

open access: yesInternational Journal of Molecular Sciences, 2019
Mycoplasma hyopneumoniae (Mhp) and porcine circovirus type 2 (PCV2) are the main pathogens for mycoplasmal pneumonia of swine (MPS) and post-weaning multisystemic wasting syndrome (PMWS), respectively.
Yu Tao   +7 more
semanticscholar   +1 more source

A 96-well format for a high-throughput baculovirus generation, fast titering and recombinant protein production in insect and mammalian cells

open access: yesBMC Research Notes, 2009
Background Baculovirus expression vector system (BEVS) has become a standard in recombinant protein production and virus-like particle preparation for numerous applications.
Roschier Miia M   +8 more
doaj   +1 more source

Controlled and customizable baculovirus NOS3 gene delivery using PVA-based hydrogel systems.

open access: yesPLoS ONE, 2023
Nitric oxide synthase 3 (NOS3) eluting polyvinyl alcohol-based hydrogels have a large potential in medical applications and device coatings. NOS3 promotes nitric oxide and nitrate production and can effectively be delivered using insect cell viruses ...
Sabrina Schaly   +7 more
doaj   +1 more source

Monobac System–A Single Baculovirus for the Production of rAAV

open access: yesMicroorganisms, 2021
Large-scale manufacturing of rAAV is a bottleneck for the development of genetic disease treatments. The baculovirus/Sf9 cell system underpins the first rAAV treatment approved by EMA and remains one of the most advanced platforms for rAAV manufacturing.
Lionel Galibert   +10 more
doaj   +1 more source

Zika Virus Baculovirus-Expressed Virus-Like Particles Induce Neutralizing Antibodies in Mice

open access: yesVirologica Sinica, 2018
The newly emerged mosquito-borne Zika virus (ZIKV) strains pose a global challenge owing to its ability to cause microcephaly and neurological disorders.
Shiyu Dai   +4 more
semanticscholar   +1 more source

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