Results 61 to 70 of about 99,639 (312)

Residual baculovirus in insect cell-derived influenza virus-like particle preparations enhances immunogenicity.

open access: yesPLoS ONE, 2012
Influenza virus-like particles are currently evaluated in clinical trials as vaccine candidates for influenza viruses. Most commonly they are produced in baculovirus- or mammalian- expression systems.
Irina Margine   +3 more
doaj   +1 more source

The Complete Genome Sequence of Plodia Interpunctella Granulovirus: Evidence for Horizontal Gene Transfer and Discovery of an Unusual Inhibitor-of-Apoptosis Gene. [PDF]

open access: yesPLoS ONE, 2016
The Indianmeal moth, Plodia interpunctella (Lepidoptera: Pyralidae), is a common pest of stored goods with a worldwide distribution. The complete genome sequence for a larval pathogen of this moth, the baculovirus Plodia interpunctella granulovirus (PiGV)
Robert L Harrison   +2 more
doaj   +1 more source

A Mammalian Homolog of Drosophila melanogaster Transcriptional Coactivator Intersex Is a Subunit of the Mammalian Mediator Complex [PDF]

open access: yes, 2003
The multiprotein Mediator complex is a coactivator required for transcriptional activation of RNA polymerase II transcribed genes by DNA binding transcription factors.
Banks, Charles A. S.   +7 more
core   +1 more source

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

open access: yesAdvanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee   +6 more
wiley   +1 more source

Gut Microbe‐Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

open access: yesAdvanced Science, EarlyView.
Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.
Ningbo HuangFu   +10 more
wiley   +1 more source

Anti-tumor activity of Escherichia coli Shiga toxin A subunit delivered by SF9 insect cells

open access: yesJournal of Pharmacological Sciences, 2018
Cancer remains a major health problem around the world. A Shiga toxin is a bacterial toxin often produced by Shigella dysenteriae and Escherichia coli. A subunit of the Shiga toxin (StxA) is a cytotoxic agent which could be used to induce death in cancer
Mana Oloomi   +5 more
doaj   +1 more source

A new single-step protocol for rapid baculovirus-driven protein production in insect cells

open access: yesBMC Biotechnology, 2017
BackgroundIn the last three decades, the Baculovirus expression vector system (BEV) has evolved to one of the most widely used eukaryotic systems for heterologous protein expression including approved vaccines and therapies.
Judith D. Scholz, S. Suppmann
semanticscholar   +1 more source

Baculovirus structural proteins

open access: yesJournal of General Virology, 1992
Introduction. Baculovirus biology. The Baculoviridae are a diverse family of virus pathogens which are infectious for arthropods, particularly insects of the order Lepidoptera. They have also been isolated from the insect orders Hymenoptera, Diptera and Trichoptera, as well as from the crustacean order Decapoda (shrimp) (Couch, 1974).
openaire   +2 more sources

Performance of large virus removal filters during AAV processing: Influence of flux and process disruptions

open access: yesBiotechnology Progress, EarlyView.
Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal   +5 more
wiley   +1 more source

Respuesta de IFN-ɤ e IL-4 en ratones inoculados con una proteína G recombinante del virus de la rabia

open access: yesRevista Mexicana de Ciencias Pecuarias, 2015
El objetivo de este estudio fue comparar el comportamiento de El objetivo de este estudio fue comparar el comportamiento de El objetivo de este estudio fue comparar el comportamiento de IFN-ɤ e IL-4 en ratones inoculados con proteína G recombinante del ...
Edith Rojas-Anaya   +6 more
doaj   +1 more source

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