Results 21 to 30 of about 9,962 (180)
Journal of Orthopaedic Surgery and Research, 2023 Background Nucleus pulposus (NP) cell apoptosis contributed to disc degeneration. Baicalein, a natural steroid saponin, has been demonstrated to have anti-inflammatory, antiapoptotic, and antioxidative effects in various diseases.
Yang Liu +4 more
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Drug Delivery, 2017 Phospholipid complex is one of the most successful approaches for enhancing oral bioavailability of poorly absorbed plant constituents. But the sticky property of phospholipids results in an unsatisfactory dissolution of drugs.
Yang Zhou +6 more
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Inhibition of p65 Nuclear Translocation by Baicalein
Toxicological Research, 2011 We demonstrate that baicalein, a bioactive flavonoid originally isolated from Scutellaria baicalensis, inhibits LPS-induced expression of iNOS gene in RAW 264.7 cells. Treatment of peritoneal macrophages and RAW 264.7 cells with baicalein inhibited LPS-stimulated nitric oxide production in a dose-related manner. Immunohistochemical staining of iNOS and
Seo, Min Bum +3 more
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Clinical and Translational Science, 2021 Baicalein is a biologically important flavonoid in extracted from the Scutellaria baicalensis Georgi, which can effectively inhibit the influenza virus. This study aimed to analyze the safety and pharmacokinetic (PK) characteristics of baicalein tablets ...
Lijun Li +7 more
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Pharmacological actions of baicalin and baicalein
Folia Pharmacologica Japonica, 1970 In the Chinese medicine, Scutellaria baicalensis GEORG has been used as a remedy for some of allergic diseases. Therefore, the authors investigated the effects of baicalin and baicalein, components of the drug, on active anaphylactic reaction in guinea pig, and the results obtained were compared with those of rutin, methylhesperidin and quercetin.
Akihide KODA +2 more
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Baicalein reduces the invasion of glioma cells via reducing the activity of p38 signaling pathway.
PLoS ONE, 2014 Baicalein, one of the major flavonids in Scutellaria baicalensis, has historically been used in anti-inflammatory and anti-cancer therapies. However, the anti-metastatic effect and related mechanism(s) in glioma are still unclear.
Zhenni Zhang +7 more
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Biotechnology & Biotechnological Equipment, 2017 Cisplatin is widely used for the treatment of a variety of cancers but with a high incidence of hepatotoxicity. Baicalein is originally isolated from the root of Scutellaria baicalensis Georgi with broad bioactivities.
Chengwei Niu +4 more
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Suppression of Very Early Stage Of Adipogenesis by Baicalein, a Plant-Derived Flavonoid through Reduced Akt-C/EBPα-GLUT4 Signaling-Mediated Glucose Uptake in 3T3-L1 Adipocytes. [PDF]
PLoS ONE, 2016 Baicalein has been used as a Chinese medicine, and is an abundant plant flavonoid present in fruits and vegetables. Here, we examined the effects of baicalein in adipogenesis and investigated its molecular mechanism in adipocytes.
Yukari Nakao +2 more
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Hepatoprotective Effect of Baicalein Against Acetaminophen-Induced Acute Liver Injury in Mice
Molecules, 2018 Baicalein (BAI), one of the main components of Scutellaria baicalensis Georgi, possesses numerous pharmacological properties, including anti-cancer, anti-oxidative, anti-virus and anti-bacterial activities.
Hong-Chao Zhou +5 more
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Enriched‐Baicalein Attenuates Allergy in Cells and Mice [PDF]
Evidence-Based Complementary and Alternative Medicine, 2020 Enriched‐baicalein (baicalein) from baicalin was prepared by fermentation of an SB extract with mycelium of Laetiporus sulphureus. To investigate the pharmacologic effects of baicalein, its antiallergic effect was measured in vitro and in vivo. Allergy was induced by intraperitoneal injection of ovalbumin (OVA) into Balb/c mice.
Mi-Young Yun +3 more
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