Results 121 to 130 of about 20,980 (270)

Systemic similarity analysis of compatibility drug-induced multiple pathway patterns _in vivo_ [PDF]

, 2008
A major challenge in post-genomic research is to understand how physiological and pathological phenotypes arise from the networks of expressed genes and to develop powerful tools for translating the information exchanged between gene and the organ system
Weida Tong, Yi Wang, Yiyu Cheng, Yongyan Wang, Zhan-jun Zhang, Zhong Wang   +5 more
core   +1 more source

A Network-Based Pharmacology Study of the Herb-Induced Liver Injury Potential of Traditional Hepatoprotective Chinese Herbal Medicines [PDF]

, 2017
published_or_final_versio
Cheung, F, Feng, Y, HONG, M, Huang, J, LI, S, Tan, HY, Wang, N   +6 more
core   +1 more source

Baicalin Inhibits NOD-Like Receptor Family, Pyrin Containing Domain 3 Inflammasome Activation in Murine Macrophages by Augmenting Protein Kinase A Signaling

Frontiers in Immunology, 2017
The flavonoid baicalin has been reported to possess potent anti-inflammatory activities by suppressing inflammatory signaling pathways. However, whether baicalin can suppress the activation of NOD-like receptor (NLR) family, pyrin containing domain 3 ...
Chen-Guang Li, Liang Yan, Feng-Yi Mai, Zi-Jian Shi, Li-Hui Xu, Yan-Yun Jing, Qing-Bing Zha, Dong-Yun Ouyang, Xian-Hui He   +8 more
doaj   +1 more source

Systematic review of the effects of the intestinal microbiota on selected nutrients and non-nutrients [PDF]

, 2017
The systematic review demonstrates that the IM plays a major role in the breakdown and transformation of the dietary substrates examined. However, recent human data are limited with the exception of data from studies examining fibres and polyphenols ...
A Belenguer, A Damms-Machado, A Everard, A Matthies, A Salonen, A Wichmann, A Woting, AA West, AB Ross, AB Ross, ACN Wong, AK Heinken, AM Fogelman, AM Neyrinck, AV Hartstra, BD Pachikian, BS Samuel, BU Metzler, BU Metzler-Zebeli, C An, C Asselin, C Bränning, C Chassard, C Lefranc-Millot, C Piazza, C Schröder, CE West, CH Nakatsu, CJ Ziemer, CL Frankenfeld, CL Frankenfeld, CR Hamilton, D Moher, D Wang, DC Nieman, EM Dewulf, EM Dewulf, F Fava, F Fava, F Vadder De, FP Martin, G Jakobsdottir, G Paturi, GC Abell, GC Abell, GD Wu, HJ Flint, I Hang, I Hwang, I Nadal, I Semova, IE François, J Doré, J Maukonen, J Overduin, J Teas, JI Ottaviani, JR Jeon, JW Lampe, K Decroos, K Ebihara, KE Andersson, L Achour, L Cloetens, L Hanske, L Shen, LA Cohen, LA David, LL Legette, LM Cox, M Durand, M Jakesevic, M Kosmala, M Kutschera, M Romo-Vaquero, M Song, M Tamura, M Tamura, M Tamura, M Urpi-Sarda, M Vincent, ME Dumas, MJ Kang, MM Ulaszewska, MR Bomhof, N Germain, N Kamal, N Matsukawa, O Deusch, O Hernández-Hernández, R Jumpertz, RC Poulsen, RF Benus, RK Le Leu, S Rahat-Rozenbloom, S Tims, S Toden, S Wiese, S Yokoyama, ST Soukup, T Clavel, TE Hedlund, TM Marques, TP Mulder, W Mullen, XY Lu, Y Kitano, Y Shimada, Y Tousen, YS Kim, Z Wang   +110 more
core   +1 more source

Targeting neurogenesis: a promising therapeutic strategy for post-stroke treatment with Chinese herbal medicine [PDF]

, 2014
published_or_final_versio
Chen, X, Chen, X, Deng, R, Shen, J
core   +1 more source

Pharmacological actions of baicalin and baicalein

Folia Pharmacologica Japonica, 1970
In the Chinese medicine, Scutellaria baicalensis GEORG has been used as a remedy for some of allergic diseases. Therefore, the authors investigated the effects of baicalin and baicalein, components of the drug, on active anaphylactic reaction in guinea pig, and the results obtained were compared with those of rutin, methylhesperidin and quercetin.
Akihide KODA, Hiroichi NAGAI, Hiroshi WADA   +2 more
openaire   +3 more sources

Unlocking the in vitroanti- inflammatory and antidiabetic potential of Polygonum maritimum [PDF]

, 2017
Context: Several Polygonum species (Polygonaceae) are used in traditional medicine in Asia, Europe and Africa to treat inflammation and diabetes. Objective: Evaluate the in vitro antioxidant, anti-inflammatory and antidiabetic potential of methanol and ...
Alice Martins, Amélia P. Rauter, Andreia Lopes, Bhandari U, Huang X, José M. F. Nogueira, João Varela, Kilinc M, Luísa Barreira, Luísa Custódio, Maria João Rodrigues, Marta Oliveira, Muriach M, Nishishiro M, Nuno R. Neng, Shai LJ, Veerasamy R   +16 more
core   +1 more source

Metformin reverses development of pulmonary hypertension via aromatase inhibition [PDF]

, 2016
Females are more susceptible to pulmonary arterial hypertension than males, although the reasons remain unclear. The hypoglycemic drug, metformin, is reported to have multiple actions, including the inhibition of aromatase and stimulation of AMP ...
Dean, Afshan, Loughlin, Lynn, MacLean, Margaret R., Nilsen, Margaret, Salt, Ian P.   +4 more
core   +2 more sources

Baicalin attenuates PD-1/PD-L1 axis-induced immunosuppression in piglets challenged with Glaesserella parasuis by inhibiting the PI3K/Akt/mTOR and RAS/MEK/ERK signalling pathways

Veterinary Research
Infection of piglets with Glaesserella parasuis (G. parasuis) induces host immunosuppression. However, the mechanism underlying the immunosuppression of piglets remains unclear.
Shulin Fu, Jingyang Li, Jiarui You, Siyu Liu, Qiaoli Dong, Yunjian Fu, Ronghui Luo, Yamin Sun, Xinyue Tian, Wei Liu, Jingyi Zhang, Yu Ding, Yitian Zhang, Wutao Wang, Ling Guo, Yinsheng Qiu   +15 more
doaj   +1 more source

The Comparative Study of the Therapeutic Effects and Mechanism of Baicalin, Baicalein, and Their Combination on Ulcerative Colitis Rat

Frontiers in Pharmacology, 2019
Introduction: Ulcerative colitis (UC) is an inflammatory bowel disease with a high incidence rate and a difficult treatment regimen. Recently, significant advances in the treatment of intestinal diseases, particularly UC, have been made with the use of ...
Shuai Liang, Xin Deng, Lei Lei, Yao Zheng, Jiao Ai, Linlin Chen, Hui Xiong, Zhinan Mei, Yung-Chi Cheng, Yongshen Ren, Yongshen Ren   +10 more
doaj   +1 more source