Diagnosis of Balamuthia mandrillaris Encephalitis by Thymine-Adenine Cloning Using Universal Eukaryotic Primers. [PDF]
Background: Identifying the causal pathogen of encephalitis remains a clinical challenge. A 50-year-old man without a history of neurological disease was referred to our department for the evaluation of an intracranial lesion observed on brain magnetic ...
Kim JY +6 more
europepmc +3 more sources
Modelling amoebic brain infection caused by Balamuthia mandrillaris using a human cerebral organoid. [PDF]
The lack of disease models adequately resembling human tissue has hindered our understanding of amoebic brain infection. Three-dimensional structured organoids provide a microenvironment similar to human tissue.
Nongnat Tongkrajang +4 more
doaj +2 more sources
Isolation and Environmental Detection of Balamuthia mandrillaris in Isfahan, Iran. [PDF]
This study investigates the presence of Balamuthia mandrillaris in environmental sources from Isfahan, Iran, and compares cultural and molecular detection methods. The findings highlight matrix‐dependent detection patterns and report an overall prevalence of 15.6%.
Lesani S, Mirzania S, Eskandarian A.
europepmc +2 more sources
An autopsy case of granulomatous amebic encephalitis caused by Balamuthia mandrillaris involving prior amebic dermatitis. [PDF]
An 82‐year‐old man, who was healthy and had worked as a farmer, experienced worsening neurological symptoms over a seven‐month period, which eventually caused his death. Multiple fluctuating brain lesions were detected radiographically. Clinically, sarcoidosis was ranked high among the differential diagnoses because of the presence of skin lesions ...
Maehara T +10 more
europepmc +2 more sources
Balamuthia mandrillaris: An opportunistic, free-living ameba - An updated review.
Balamuthia mandrillaris is an opportunistic, free-living ameba that is pathogenic to humans. It has a worldwide distribution but is mainly detected in warmer regions. Balamuthia infections are rare but have been reported in both immunocompetent and immunocompromised individuals of all ages. B.
Bhosale NK, Parija SC.
europepmc +3 more sources
Post-mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells [PDF]
The first isolation in the UK of Balamuthia mandrillaris amoebae from a fatal case of granulomatous amoebic meningoencephalitis is reported. Using primary cultures of human brain microvascular endothelial cells (HBMECs), amoebae were isolated from the ...
Alsam +32 more
core +2 more sources
Guidelines for the purification and characterization of extracellular vesicles of parasites
Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs) has increased in recent years and demonstrated that EVs shed by pathogenic parasites ...
Carmen Fernandez‐Becerra +30 more
wiley +1 more source
Disseminated Balamuthia mandrillaris Infection [PDF]
ABSTRACTBalamuthia mandrillarisis a rare cause of human infection, but when infections do occur, they result in high rates of morbidity and mortality. A case of disseminatedBalamuthiainfection is presented. Early diagnosis and initiation of recommended therapy are essential for increased chances of successful outcomes.
Katherine R, Schafer +7 more
openaire +2 more sources
Free‐Living Amoebas in Extreme Environments: The True Survival in our Planet
Free‐living amoebas (FLAs) are microorganisms, unicellular protozoa widely distributed in nature and present in different environments, such as water or soil; they are maintained in ecosystems and play a fundamental role in the biological control of bacteria, other protozoa, and mushrooms.
Camila Salazar-Ardiles +3 more
wiley +1 more source

