Results 21 to 30 of about 3,228 (214)

Aristolochic acid I induces proximal tubule injury through ROS/HMGB1/mt DNA mediated activation of TLRs

open access: yesJournal of Cellular and Molecular Medicine, Volume 26, Issue 15, Page 4277-4291, August 2022., 2022
Abstract Aristolochic acids (AAs) are extracted from certain plants as folk remedies for centuries until their nephrotoxicity and carcinogenicity were recognized. Aristolochic acid I (AAI) is one of the main pathogenic compounds, and it has nephrotoxic, carcinogenic and mutagenic effects.
Rohit Upadhyay, Vecihi Batuman
wiley   +1 more source

Occurrence of ochratoxin A and citrinin in Czech cereals and comparison of two HPLC methods for ochratoxin A detection. [PDF]

open access: yes, 2010
The aims of the study were to obtain information about the occurrence of ochratoxin A (OTA) and citrinin (CIT) in cereals harvested in the Czech Republic and to compare two analytical procedures for detecting OTA.
Denesova, Olga   +7 more
core   +2 more sources

Two decades of chronic kidney disease of unknown aetiology (CKDu) research: Existing evidence and persistent gaps from epidemiological studies in Sri Lanka

open access: yesNephrology, Volume 27, Issue 3, Page 238-247, March 2022., 2022
Abstract Background Chronic Kidney Disease of unknown origin (CKDu) excludes known primary renal conditions or systemic disease (such as diabetes mellitus or hypertension). Prominence of CKDu has been noted for some decades in Sri Lanka, especially among men in particular rural areas, prompting many studies directed towards environmental causation ...
Jennifer Pett   +5 more
wiley   +1 more source

Ochratoxin A: 50 Years of Research

open access: yesToxins, 2016
Since ochratoxin A (OTA) was discovered, it has been ubiquitous as a natural contaminant of moldy food and feed. The multiple toxic effects of OTA are a real threat for human beings and animal health.
Frantisek Malir   +4 more
doaj   +1 more source

Molecular profiles and urinary biomarkers of upper tract urothelial carcinomas associated with aristolochic acid exposure

open access: yesInternational Journal of Cancer, Volume 150, Issue 2, Page 374-386, 15 January 2022., 2022
Abstract Recurrent upper tract urothelial carcinomas (UTUCs) arise in the context of nephropathy linked to exposure to the herbal carcinogen aristolochic acid (AA). Here we delineated the molecular programs underlying UTUC tumorigenesis in patients from endemic aristolochic acid nephropathy (AAN) regions in Southern Europe.
Sandra Karanović   +19 more
wiley   +1 more source

Research and application of herbal medicine in the treatment of chronic kidney disease since the 21st century: A visualized bibliometric analysis

open access: yesFrontiers in Pharmacology, 2022
Background: Here, a bibliometric and knowledge-map analysis was used to analyze the research status and application of herbal medicine for the treatment of chronic kidney disease (CKD).
Yunling Xu, Jia Chen, He Wang, Ying Lu
doaj   +1 more source

Early Detection of Balkan Endemic Nephropathy in Bosanska Posavina

open access: yesBiomolecules & Biomedicine, 2010
Balkan endemic nephropathy (BEN) is a chronic tubulointersticial nephropathy that is diagnosed in a few agrarian regions of Balkan. Even tough numerous dilemmas and conflicting opinions regarding BEN etiology are encountered in literature, prevailing ...
Enisa Mešić
doaj   +1 more source

Higher dose of erythropoietin for anemia correction in Balkan endemic nephropathy patients [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2012
Introduction. Balkan endemic nephropathy (BEN) patients maintained with hemodialysis have more severe anemia than patients with other kidney diseases. Objective.
Lukić Ljiljana   +7 more
doaj   +1 more source

c-Jun Amino Terminal Kinase Signaling Promotes Aristolochic Acid-Induced Acute Kidney Injury

open access: yesFrontiers in Physiology, 2021
Aristolochic acid (AA) is a toxin that induces DNA damage in tubular epithelial cells of the kidney and is the cause of Balkan Nephropathy and Chinese Herb Nephropathy.
Fan Yang   +7 more
doaj   +1 more source

Simultaneous ipsilateral rhabdoid renal cell carcinoma and multifocal urothelial carcinoma of the ureter in a patient from the region of Balkan endemic nephropathy: Case report and literature review [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2021
Introduction. Simultaneous ipsilateral coexistence of renal cell carcinoma (RCC) and upper urinary tract urothelial carcinoma (UTUC) rarely occurs. Balkan endemic nephropathy (BEN) is a chronic degenerative tubulointerstitial renal disease, strongly ...
Bašić Dragoslav   +4 more
doaj   +1 more source

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