Results 71 to 80 of about 3,228 (214)

Association of SOD2 (rs4880) and GPX1 (rs1050450) Gene Polymorphisms with Risk of Balkan Endemic Nephropathy and its Related Tumors

Medicina, 2019
Background and Objectives: Experimental data show that superoxide dismutase 2 (SOD2) is involved in ochratoxin (OTA)-induced nephrotoxicity, whereas clinical data indicate the role of SOD2 rs4880 or glutathione peroxidase 1 (GPX1) rs1050450 polymorphisms
Biljana Dragicevic, Sonja Suvakov, Djurdja Jerotic, Zorica Reljic, Ljubica Djukanovic, Ivanka Zelen, Marija Pljesa-Ercegovac, Ana Savic-Radojevic, Tatjana Simic, Dejan Dragicevic, Marija Matic   +10 more
doaj   +1 more source

Does ochratoxin A (OTA) cause testicular cancer in humans?

Acta Medica Lituanica, 2011
Ochratoxin A (OTA) is a naturally occurring contaminant of cereals, pigmeat, and other foods and is a known genotoxic in animals. It is a nephrotoxin and a carcinogen associated with Balkan endemic nephropathy and urinary tract tumours.
Jayachandra SRINIVASA
doaj   +1 more source

Mould and mycotoxin contamination of pig and poultry feed [PDF]

, 2005
During ten-year period (1995-2004), a total of 756 analyses of pig and poultry feed was performed. Standard methods were used for microbiological determination. Qualitative and quantitative analyze of mycotoxins was performed by TLC technique.
Jovanović Nebojša D., Marković Radmila V., Sinovec Zlatan J., Šefer Dragan S.   +3 more
core   +1 more source

Apoptoza u bubrežnom tkivu štakora uzrokovana okratoksinom A [PDF]

, 2004
The aim of our study was to find whether ochratoxin A (OTA) induces the apoptosis and/or necrosis of kidney tissue in rats. In the first experiment, the highest number of apoptotic cells was found in rats sacrificed one day after OTA administration (1.00
Ana Lucić, Ana-Marija Domijan, Božica Radić, Maja Peraica, Radovan Fuchs, Snježana Čužić, Željko Ferenčić   +6 more
core   +1 more source

Association of ABCB1 genetic variants with renal function in Africans and in Caucasians. [PDF]

, 2008
: BACKGROUND: The P-glycoprotein, encoded by the ABCB1 gene, is expressed in human endothelial and mesangial cells, which contribute to control renal plasma flow and glomerular filtration rate. We investigated the association of ABCB1 variants with renal
Beckmann, J.S., Bergmann, S., Bochud, M., Bovet, P., Burnier, M., Eap, C.B., Elston, R.C., Gabriel, A., Johnson, T., Maillard, M., Mooser, V., Vollenweider, P., Waterworth, D.M.   +12 more
core   +2 more sources

Ocratoxins and their nephrotoxic potential

Revista de Nefrología, Diálisis y Trasplante, 2019
Ochratoxins are fungal metabolites that are present in a wide variety of foods and their byproducts. Nephrotoxicity is its main toxic effect, related in turn to different clinical syndromes such as tubular necrosis or Balkan nephropathy.
Cristhian Camilo Martínez Torres, Diana Carolina Chaves Silva   +1 more
doaj  

Glomerular Filtration Rate in Examined Population of Bosnian Posavina - Region of Balkan Endemic Nephropathy

Biomolecules & Biomedicine, 2010
Balkan endemic nephropathy (BEN) is chronic tubulointersticial nephritis of unknown aetiology characterized by an insidious onset and gradual progression to end stage renal disease (ESRD).
Mirna Alečković, Enisa Mešić, Senaid Trnačević, Želimir Stipančić, Damir Hamidović, Evlijana Hasanović   +5 more
doaj   +1 more source

Exploration of Apoptosis in Histopathologies of Balkan Endemic Nephropathies with Both Urothelial Tumour and Atrophied Kidney

Annals of Urologic Oncology
There seems yet no satisfactory explanation for the mysterious endemic renal disease, known as Balkan endemic nephropathy (BEN), seen across rural parts of several Balkan countries in the last century although some have claimed aristolochic acid as the ...
Peter Mantle, Rohit Upadhyay, Diana Herman, Vecihi Batuman   +3 more
doaj   +1 more source

Djelovanje okratoksina A na proteinske karbonile u bubregu i jetri štakora [PDF]

, 2005
The mechanism of ochratoxin A (OTA) toxicity has been found to involve the production of free radicals and consequent oxidative stress. Until now, the only studied pathway of OTA-caused oxidative damage was peroxidation of lipids.
Ana-Marija Domijan, Kamilo Rudeš, Maja Peraica   +2 more
core   +1 more source

Is Increased Susceptibility to Balkan Endemic Nephropathy in Carriers of Common GSTA1 (*A/*B) Polymorphism Linked with the Catalytic Role of GSTA1 in Ochratoxin A Biotransformation? Serbian Case Control Study and In Silico Analysis

Toxins, 2014
Although recent data suggest aristolochic acid as a putative cause of Balkan endemic nephropathy (BEN), evidence also exists in favor of ochratoxin A (OTA) exposure as risk factor for the disease.
Zorica Reljic, Mario Zlatovic, Ana Savic-Radojevic, Tatjana Pekmezovic, Ljubica Djukanovic, Marija Matic, Marija Pljesa-Ercegovac, Jasmina Mimic-Oka, Dejan Opsenica, Tatjana Simic   +9 more
doaj   +1 more source