Results 101 to 110 of about 128,512 (289)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
AmpersandProblem-based Learning, an instructional approach focused on solving real-world problems, fosters self-guided learning under a facilitator's direction.
Saieed Moslemi Nezhad Arani
doaj +1 more source
Functional and mutational analysis of the light-harvesting chlorophyll a/b protein of thylakoid membranes. [PDF]
, 1986 The precursor for a Lemna light-harvesting chlorophyll a/b protein (pLHCP) has been synthesized in vitro from a single member of the nuclear LHCP multigene family. We report the sequence of this gene.
Chitnis, PR +4 more
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Meditation smartphone application effects on prehypertensive adults' blood pressure: Dose-response feasibility trial [PDF]
, 2018 OBJECTIVE: Essential hypertension (EH) is the most common chronic disease in the United States and a major cause of morbidity and mortality. Lifestyle interventions (e.g., diet, exercise, stress management) to reduce blood pressure (BP) are often ...
Adams, Zachary W. +9 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Size and morphology control of ultrafine refractory complex oxide crystals [PDF]
, 2011 High-temperature complex oxides are of considerable interest as their applications cover a broad spectrum from catalytic to optical technology. Indeed, new exciting opportunities might emerge if these high-temperature complex oxides, in which structure ...
Airiau, Marc +5 more
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Weak core and central weak core inverse in a proper $*$-ring
, 2020 In this paper, we introduce the notion of weak core and central weak core inverse in a proper $*$-ring. We further elaborate on these two classes by producing a few representation and characterization of the weak core and central weak core invertible ...
Behera, Ratikanta +2 more
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Interviewing Women Again: Power, Time and the Gift [PDF]
, 2016 The starting point for this article is a contribution to qualitative research methodology published in 1981 called ‘Interviewing women: A contradiction in terms?’ This was based on the experience of interviewing women in a longitudinal study of the ...
Oakley, A
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