Results 51 to 60 of about 883,268 (297)

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte   +5 more
wiley   +1 more source

The Bialaphos Resistance Gene (bar) Plays a Role in Both Self-Defense and Bialaphos Biosynthesis in Streptomyces hygroscopicus [PDF]

open access: yes, 1988
We inactivated the bialaphos (BA) resistance gene (bar) of a BA producer, Streptomyces hygroscopicus, by the gene replacement technique. The resulting BA-sensitive mutant (Bar-) was able to produce little BA but considerable amount of an intermediate ...
Takano, E.; id_orcid   +26 more
core   +1 more source

Gene Ontology (GO) bar chart of differentially expressed genes between parthenotes and fertilised embryos. [PDF]

open access: yes, 2013
Gene Ontology (GO) bar chart of differentially expressed genes between parthenotes and in vivo fertilised embryos. Genes upregulated and downregulated in parthenotes embryos that are categorised by GO term “Molecular function” level 4.
María dels Desamparats Saenz-de-Juano (294489)   +4 more
core   +5 more sources

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver   +25 more
wiley   +1 more source

Transformation of Lotus japonicus using the herbicide resistance bar gene as a selectable marker [PDF]

open access: yes, 2001
Transgenic plants of the model legume Lotus japonicus were regenerated by hypocotyl transformation using a bar gene as a selectable marker. The bar encodes for Phosphinothricin Acetyl Transferase that detoxifies phosphinothricin (PPT), the active ...
Buzas, D. M.   +4 more
core   +3 more sources

Aluminium Borate Whisker-Mediated DNA Delivery into Callus of Rice and Production of Transgenic Rice Plant

open access: yesPlant Production Science, 2000
Japonica rice ( Oryza sativa L., cv. Notohikari) was transformed by the use of aluminium borate whiskers (ABW) to deliver DNA into the scutellar tissues of embryos isolated from mature seeds. DNA delivery was mediated by mixing ABW and plasmid DNA.
Wataru Takahashi   +3 more
doaj   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris   +24 more
wiley   +1 more source

A Single-Step Photolithographic Interface for Cell-Free Gene Circuits [PDF]

open access: yes, 2007
We have developed a biochip platform technology suitable for controlled cell-free gene expression at the micrometer scale. A new hybrid molecule, “Daisy”, was designed and synthesized to form in a single step a biocompatible lithographic interface on ...
BAR DAGAN M   +5 more
core  

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

Classification with binary gene expressions [PDF]

open access: yes, 2009
Microarray gene expression measurements are reported, used and archived usually to high numerical precision. However, properties of mRNA molecules, such as their low stability and availability in small copy numbers, and the fact that measurements ...
Tuna, Salih   +3 more
core  

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