Results 81 to 90 of about 3,963,937 (304)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Proceedings of the State Bar Association of North Dakota.

open access: yes, 1905
First volume includes Proceedings...from its organization, September 19, 1899, to and including the annual meeting of September 21, 1904.Mode of access: Internet.1899/1904-1909 issuing body known as North Dakota Bar Association; 1910-1927 as Bar ...
State Bar Association of North Dakota.
core  

Syriac lexicon Hasan Bar Bahlul. Volume 2

open access: yes, 1886
The massive Syriac-Syriac/Arabic lexicon—actually more an encyclopedia than a mere lexicon—of Bar Bahlul (10th century) is one of two commonly cited Syriac dictionaries from the medieval period, the other being that of Bar Ali.

core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Cross-Platform Analysis with Binarized Gene Expression Data

open access: yes, 2009
With widespread use of microarray technology as a potential diagnostics tool, the comparison of results obtained from the use of different platforms is of interest.
Tuna, Salih   +3 more
core   +2 more sources

Lockwood Letter. (Toledo, Ohio), April 1986

open access: yes, 2019
The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Lockwood Letter. (Toledo, Ohio), July 1991

open access: yes, 2019
The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
core  

Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis [PDF]

open access: yes, 2010
Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic ...
S Eyre   +21 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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