Results 111 to 120 of about 48,209 (275)

Верификација на квалитативни методи Ñо теÑÑ‚ ленти за иÑпитување на дроги кои Ñе злоупотребуваат во урина [PDF]

open access: yes, 2018
The verification of the  qualitative method with test  devices for detection of eight drugs of abuse in urine  (amphetamines, methamphetamine,  barbiturates,  benzoylecgonine,  marijuana, 3,4-methylendioxy-methamphetamine, methadone, and opiates) was ...
ТопузовÑка (Topuzovska), Соња (Sonja)   +4 more
core   +1 more source

Phenobarbital Bioequivalence in Chinese Population: Considering the Role of Food on Pharmacokinetics

open access: yesClinical Pharmacology in Drug Development, Volume 14, Issue 12, Page 925-933, December 2025.
Abstract Epilepsy is one of the most severe neurological disorders in the world, which might seriously endanger the lives of patients. Phenobarbital is an important medicine clinically used for the treatment of epilepsy, and it is irreplaceable in the treatment of generalized tonic–clonic seizures, focal seizures, status epilepticus, and pediatric ...
Wang Xinman   +3 more
wiley   +1 more source

More on Barbiturate-related Hyperalgesia [PDF]

open access: bronze, 1995
Anand Tewari   +2 more
openalex   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +86 more
wiley   +1 more source

Synthesis and spectroscopic characterization of 5-diaminomethylidene barbiturates

open access: yesJournal of the Brazilian Chemical Society, 2001
The reaction of amines with dithiocyclohexylidenes is a general reaction for the synthesis of diaminomethylidene barbiturates. When diamines of the type H2N-(CH2)n-NH 2 are used as nucleophiles bicyclic compounds are the major reaction products, with ...
Figueroa-Villar José D.   +2 more
doaj  

Prevalence and Duration of Potential Drug–Drug Interactions Among US Nursing Home Residents, 2018–2020

open access: yesJournal of the American Geriatrics Society, Volume 73, Issue 12, Page 3766-3777, December 2025.
ABSTRACT Background Nursing home (NH) residents are at increased risk of drug–drug interactions (DDIs) due to multimorbidity and polypharmacy. While prior research suggests that many DDIs lead to adverse drug events in older adults, the extent of exposure to potentially clinically relevant DDIs among United States (US) NH residents is largely unknown ...
Laura A. Reich   +9 more
wiley   +1 more source

SYNTHESIS OF NEW PHASE- 1 METABOLITES OF TWO BARBITURATES [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 1990
The new 4'- hydroxy and 3'- aldehyde phase- 1 metabolites of butobarbitone and pentobarbitone are fully synthesized for the first time. These metabolites were used to idenfity and quantify the natural metabolites in human urine after single and multiple ...
doaj  

Oral KDS2010, a Monoamine Oxidase‐B (MAO‐B) Inhibitor, Slows the Deterioration of Motor Coordination in Genetic SCA1 Models by Inhibiting Astrocytic MAO‐B‐Mediated Inflammation

open access: yesJournal of Neurochemistry, Volume 169, Issue 12, December 2025.
Astrocytes play a critical role in neurodegenerative disease pathology by modulating inflammatory responses and clearing toxic protein aggregates. In this study, we evaluated the therapeutic potential of KDS2010, a reversible and selective MAO‐B inhibitor, in a mouse model of spinocerebellar ataxia type 1 (SCA1).
Dong Ho Woo   +7 more
wiley   +1 more source

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