Results 41 to 50 of about 19,466 (148)

Guidelines for euthanasia of laboratory animals used in biomedical research [PDF]

Medicamentul Veterinar, 2012
Laboratory animals are used in several fields of science research, especially in biology, medicine and veterinary medicine. The majority of laboratory animals used in research are experimental models that replace the human body in study regarding ...
Adina Baias,, Cristina, T. Romeo, Viorica Chiurciu   +2 more
doaj  

Overview: eutanasia and methods of antanasia of animals

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2022
The attention of modern society to euthanasia has increased because many centuries ago, a social phenomenon was established, associated not only with the achievements of medical science but also with changing values of the individual and society ...
S. Nichiporuk, M. Radzykhovskyi, B. Gutyj   +2 more
doaj   +1 more source

Asymmetric Organocatalytic Synthesis of Sulfone‐Containing (Dihydro)pyrans via Formal (4+2)‐Cycloadditions of Allenylsulfones or Propargylsulfones and Michael Acceptors

ChemCatChem, Accepted Article.
The activation of electron poor allenes with Lewis base catalysts allows for unique transformations and chiral isochalcogenoureas were recently introduced as powerful catalysts for allenoate‐based (4+2)‐cycloadditions. We herein now report the use of these catalysts for the activation and control of allenylsulfones and propargylsulfones for asymmetric (
Mario Hofer, Markus Himmelsbach, Uwe Monkowius, Mario Waser   +3 more
wiley   +1 more source

Multigram‐Scale Organic Synthesis by Resonant Acoustic Mixing: Application to the Sustainable Preparation of Active Pharmaceutical Ingredients

ChemSusChem, EarlyView.
Knoevenagel condensation, Biginelli three‐component reaction and benzylic rearrangement are investigated at multi‐gram scale, by resonance acoustic mixing (RAM), to prepare biologically active molecules, also including the marketed Phenytoin (antiepileptic drug). Chem21 and DOZN 3.0 tools were used to assess the greenness of the RAM‐assisted syntheses,
Christos M. Chatzigiannis, Stefania M. Scalzullo, Evelina Colacino, Maria Elena Rivas   +3 more
wiley   +1 more source

Assessment of Controlled Substance Distribution to U.S. Veterinary Teaching Institutions From 2006 to 2019

Frontiers in Veterinary Science, 2020
Objective: To evaluate the changing pattern of distribution of Schedule II and III opioids, barbiturates, and stimulants to veterinary educational institutions in the United States.Design: Longitudinal study.Sample: Veterinary teaching institutions that ...
Brian J. Piper, Brian J. Piper, Kenneth L. McCall, Lori R. Kogan, Peter Hellyer   +4 more
doaj   +1 more source

Increased GABA(A) receptor ε-subunit expression on ventral respiratory column neurons protects breathing during pregnancy. [PDF]

PLoS ONE, 2012
GABAergic signaling is essential for proper respiratory function. Potentiation of this signaling with allosteric modulators such as anesthetics, barbiturates, and neurosteroids can lead to respiratory arrest.
Keith B Hengen, Nathan R Nelson, Kyle M Stang, Stephen M Johnson, Stephanie M Crader, Jyoti J Watters, Gordon S Mitchell, Mary Behan   +7 more
doaj   +1 more source

Infant Death due to Cannabis Ingestion

Drug Testing and Analysis, EarlyView.
ABSTRACT A child died in the emergency room of a local hospital a few hours after ingesting a substance the color of cork and the consistency of earth. At home, a modest amount of resinous substance was found. At the hospital, the child exhibited alterations in walking, balance, and consciousness.
Donata Favretto, Antonello Cirnelli, Roberto Pertile, Raffaella Stimamiglio, Clara Cestonaro, Oriana Cuman, Anna Pagliaro, Fabio Mattiazzi, Cristina Basso, Maddalena Galeazzi   +9 more
wiley   +1 more source

Determination of barbiturates in hair samples by using a validated UHPLC-HRMS method: application in investigation of drug-facilitated sexual assault

Forensic Sciences Research, 2019
In recent years, benzodiazepines and benzodiazepine-like drugs are the most common substances associated with drug-facilitated sexual assaults (DFSA); however, barbiturates are also detected occasionally.
Di Wen, Yan Shi, Xiaoguang Zhang, Bing Xie, Wenqiao Liu, Feng Yu, Ping Xiang, Bin Cong, Chunling Ma   +8 more
doaj   +1 more source

Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod

Developmental Dynamics, EarlyView.
Abstract Background Bones develop to structurally balance strength and mobility. Bone developmental dynamics are influenced by whether an animal is ambulatory at birth. Precocial species, which are ambulatory at birth, develop advanced skeletal maturity in utero and experience postnatal development under mechanical loading.
Christopher J. Panebianco, Maha Essaidi, Elijah Barnes, Ashley Williams, Karin Vancíková, Margot C. Labberté, Pieter Brama, Niamh C. Nowlan, Joel D. Boerckel   +8 more
wiley   +1 more source

Practical management of repeated life‐threatening status epilepticus in Alternating Hemiplegia of Childhood: Case report and literature review

Epileptic Disorders, EarlyView.
Abstract Background Alternating Hemiplegia of Childhood (AHC) is a severe channelopathy that manifests before 18 months of age, primarily caused by pathogenic variants in the ATP1A3 gene. It is characterized by recurrent and disabling episodes of plegia, dystonia, dysautonomia, along with chronic neurological features and cardiac arrhythmias. About 50%
Ramona Cordani, Livia Pisciotta, Michela Stagnaro, Maria Margherita Mancardi, Elisabetta Lampugnani, Luca Manfredini, Lino Nobili, Edvige Veneselli, Elisa De Grandis   +8 more
wiley   +1 more source