Results 41 to 50 of about 48,209 (275)

Case report: Fatal poisoning caused by additive effects of two barbiturates

open access: yesFrontiers in Pharmacology, 2023
A case of fatal poisoning involving multiple psychotropic drugs is presented. Quantitative toxicological analysis showed femoral blood concentrations of pentobarbital, phenobarbital, duloxetine, acetaminophen and tramadol were 10.39, 22.57, 0.22, 0.61 ...
Sella Takei   +9 more
doaj   +1 more source

Antigen-specific electrophoretic cell separation for immunological investigations [PDF]

open access: yes, 1989
Preincubation of human blood lymphocytes with cell surface antigen specific antibodies under non-capping conditions reduces the electrophoretic mobility of the corresponding lymphocyte subpopulation.
Hannig, K.   +2 more
core   +1 more source

Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Bones develop to structurally balance strength and mobility. Bone developmental dynamics are influenced by whether an animal is ambulatory at birth. Precocial species, which are ambulatory at birth, develop advanced skeletal maturity in utero and experience postnatal development under mechanical loading.
Christopher J. Panebianco   +8 more
wiley   +1 more source

Increased GABA(A) receptor ε-subunit expression on ventral respiratory column neurons protects breathing during pregnancy. [PDF]

open access: yesPLoS ONE, 2012
GABAergic signaling is essential for proper respiratory function. Potentiation of this signaling with allosteric modulators such as anesthetics, barbiturates, and neurosteroids can lead to respiratory arrest.
Keith B Hengen   +7 more
doaj   +1 more source

Potentiometric measurement of barbituric acid by integration of supramolecular receptors into ChemFETs

open access: yesSensing and Bio-Sensing Research, 2021
Potentiometric sensing devices were prepared based on ion-selective membranes (ISM) containing Hamilton-type receptors incorporated into polymer membranes.
Grace M. Kuhl   +4 more
doaj   +1 more source

A prospective randomized crossover trial investigating melatonin versus sleep deprivation for sleep induction in nap electroencephalography

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Electroencephalography (EEG) plays a fundamental role in the diagnosis and classification of epilepsy, and inducing sleep during EEG can improve patient cooperation and enhance the detection of epileptiform activity. Despite its importance, there is currently no standardized approach for sleep induction in pediatric EEG recordings ...
Valentina De Giorgis   +11 more
wiley   +1 more source

A Randomized Trial for the Treatment of Refractory Status Epilepticus [PDF]

open access: yes, 2018
Background: Refractory status epilepticus (RSE) has a mortality of 16-39%; coma induction is advocated for its management, but no comparative study has been performed. We aimed to assess the effectiveness (RSE control, adverse events) of the first course
Bertschi, Manuel   +5 more
core  

A modified technique of orthotopic transplant of the kidney in rabbits [PDF]

open access: yes, 1989
In this study kidneys were harvested from bred-for-research cats weighing 4 to 5 kg. General principles of donor bilateral nephrectomy en bloc with aorta, vena cava, renal vessels, and ureters were followed.
Banner, B   +10 more
core   +2 more sources

Vanillin Modulates the Sedative Effect of Diazepam, Possibly Through GABAergic Interaction Pathways in Thiopental Sodium‐Induced Sleeping Mice

open access: yesFood Safety and Health, EarlyView.
Vanillin showed moderate sedative and modulatory synergistic activities on diazepam in thiopental sodium‐induced sleeping mice. These effects are implicated with GABAergic intervention. ABSTRACT Insomnia is a common sleep disorder affecting approximately 10% of adults.
Salehin Sheikh   +8 more
wiley   +1 more source

Guidelines for euthanasia of laboratory animals used in biomedical research [PDF]

open access: yesMedicamentul Veterinar, 2012
Laboratory animals are used in several fields of science research, especially in biology, medicine and veterinary medicine. The majority of laboratory animals used in research are experimental models that replace the human body in study regarding ...
Adina Baias,   +2 more
doaj  

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