Results 71 to 80 of about 19,466 (148)

Potentiometric measurement of barbituric acid by integration of supramolecular receptors into ChemFETs

Sensing and Bio-Sensing Research, 2021
Potentiometric sensing devices were prepared based on ion-selective membranes (ISM) containing Hamilton-type receptors incorporated into polymer membranes.
Grace M. Kuhl, Daniel T. Seidenkranz, Michael D. Pluth, Darren W. Johnson, Sean A. Fontenot   +4 more
doaj  

Dreaming of Better Treatments: Advances in Drug Development for Sleep Medicine and Chronotherapy

Journal of Sleep Research, EarlyView.
ABSTRACT Throughout history, the development of new sleep medicines has been driven by progress in our understanding of the mechanisms underlying sleep. Ancient civilisations used their understanding of the sedative nature of natural herbs and compounds to induce sleep.
Brooke A. Prakash, Ishani Shah, Guohao Ni, Sridhar Vasudevan, Aarti Jagannath, Russell G. Foster   +5 more
wiley   +1 more source

Cost‐Effective Nanosensor Solutions for Ultra‐Sensitive Detection of Metronidazole

Analytical Science Advances, Volume 6, Issue 1, June 2025.
ABSTRACT Metronidazole (MNZ) is a widely used imidazole antibiotic effective against bacterial and protozoal infections, including giardiasis, trichomoniasis, bacterial vaginosis, and antibiotic‐associated colitis. However, prolonged and excessive use of MNZ can lead to serious side effects, such as peripheral neuropathies, toxicity, and optic ...
Ahmad Mobed, Mohammad Darvishi, Vahid Alivirdiloo, Sara Ebrahimi, Mobasher Hajiabbasi, Farhood Ghazi, Hamidreza Hassanzadeh Khanmiri   +6 more
wiley   +1 more source

Presumptive Tests for Xylazine—A Computer Vision Approach

Analytical Science Advances, Volume 6, Issue 1, June 2025.
ABSTRACT Abuse of xylazine is an immediate global public health concern. We report the distinct and measurable colour changes when xylazine is exposed to the Mandelin, Marquis and Mecke presumptive test reagents. The colour changes observed with xylazine are distinct from those of drugs that give colour changes from the same presumptive tests.
Hui Yun Chang, Kristin Donnachie, Timothy J. D. McCabe, Henry Barrington, Felicity Carlysle‐Davies, Kristin Ceniccola‐Campos, Marc Reid   +6 more
wiley   +1 more source

Neuropsychiatric Symptoms and White Matter Hyperintensities in Older Cognitively Unimpaired Men Versus Women

International Journal of Geriatric Psychiatry, Volume 40, Issue 6, June 2025.
ABSTRACT Objectives We aimed to examine association patterns of white matter hyperintensities (WMH) with neuropsychiatric symptoms (NPS) in men versus women. Methods We performed a cross‐sectional analysis of data acquired from the National Alzheimer's Coordinating Center database.
Ioannis Liampas, Daniil Tsirelis, Silvia Demiri, Vasileios Siokas, Antonia Tsika, Elli Zoupa, Polyxeni Stamati, Lambros Messinis, Grigorios Nasios, Efthimios Dardiotis   +9 more
wiley   +1 more source

Supramolecular Brake for Slowing Fentanyl Into Brain to Ameliorate Its Therapeutic Outcome

SmartMat, Volume 6, Issue 3, June 2025.
An effective and universal supramolecular brake strategy for ameliorating the therapeutic outcome of fentanyl analogs has been proposed via simply host–guest recognition. Coadministration with well‐matched macrocyclic hosts decelerates the velocity of entering the brain of guest drugs, thereby alleviating respiratory depression caused by them.
Longming Chen, Kaili Jiang, Yuanyuan Liu, Mengran Song, Yibo Zhao, Chengyang Tian, Yahan Zhang, Ziliang Zhang, Xiang Yu, Junhai Xiao, Junyi Chen, Zheng Yong, Chunju Li, Qingbin Meng   +13 more
wiley   +1 more source

Best practices for blood collection and anaesthesia in mice: Selection, application and reporting

British Journal of Pharmacology, Volume 182, Issue 11, Page 2337-2353, June 2025.
Abstract Blood collection in mice is a common procedure in biomedical research. The choice of blood collection method and the need for analgesia and/or anaesthesia depend on multiple factors, including the experimental setup, animal welfare considerations and the intended downstream analyses.
Zhixin Li, Anthea LoBue, Sophia K. Heuser, Junjie Li, Eva Engelhardt, Andreas Papapetropoulos, Hemal H. Patel, Elliot Lilley, Péter Ferdinandy, Rainer Schulz, Miriam M. Cortese‐Krott   +10 more
wiley   +1 more source

Brain pathology caused in the neonatal macaque by short and prolonged exposures to anticonvulsant drugs

Neurobiology of Disease, 2021
Barbiturates and benzodiazepines are potent GABAA receptor agonists and strong anticonvulsants. In the developing brain they can cause neuronal and oligodendroglia apoptosis, impair synaptogenesis, inhibit neurogenesis and trigger long-term ...
Kevin K. Noguchi, Nicole A. Fuhler, Sophie H. Wang, Saverio Capuano, III, Kevin R. Brunner, Shreya Larson, Kristin Crosno, Heather A. Simmons, Andres F. Mejia, Lauren D. Martin, Gregory A. Dissen, Ansgar Brambrink, Chrysanthy Ikonomidou   +12 more
doaj  

Antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID)

Veterinary Dermatology, Volume 36, Issue 3, Page 234-282, June 2025.
Background – Canine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing. Objectives – To provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including those involving meticillin‐resistant staphylococci.
Anette Loeffler, Christine L. Cain, Lluís Ferrer, Koji Nishifuji, Katarina Varjonen, Mark G. Papich, Luca Guardabassi, Siân M. Frosini, Emi N. Barker, J. Scott Weese   +9 more
wiley   +1 more source

Rapid visualization of fingerprints on various surfaces using ZnO superstructures prepared via simple combustion route

Journal of Science: Advanced Materials and Devices, 2018
A simple solution combustion route has been used to prepare ZnO nanopowders (NPs) using different barbiturates (Barbituric acid, 1, 3-dimethyl barbiturates and 2-thiobarbiturates) as fuels.
N.H. Deepthi, R.B. Basavaraj, S.C. Sharma, J. Revathi, Ramani, S. Sreenivasa, H. Nagabhushana   +6 more
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