Results 61 to 70 of about 91,234 (296)

Plant species distribution along environmental gradient: do belowground interactions with fungi matter?

Frontiers in Plant Science, 2013
The distribution of plants along environmental gradients is constrained by abiotic and biotic factors. Cumulative evidence attests of the impact of abiotic factors on plant distributions, but only few studies discuss the role of belowground communities ...
Loïc ePellissier, Eric ePinto, Hélène eNiculita-Hirzel, Mari eMoora, Lucas eVillard, Jérome eGoudet, Nicolas eGuex, Marco ePagni, Ioannis eXenarios, Ian eSanders, Antoine eGuisan   +10 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Using Environmental DNA to Improve Species Distribution Models for Freshwater Invaders

Frontiers in Ecology and Evolution, 2017
Species Distribution Models (SDMs) have been reported as a useful tool for the risk assessment and modeling of the pathways of dispersal of freshwater invasive alien species (IAS).
Teja P. Muha, Marta Rodríguez-Rey, Matteo Rolla, Elena Tricarico   +3 more
doaj   +1 more source

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo

Nature, 2017
Developmental deconvolution of complex organs and tissues at the level of individual cells remains challenging. Non-invasive genetic fate mapping has been widely used, but the low number of distinct fluorescent marker proteins limits its resolution. Much
Weike Pei, T. Feyerabend, Jens Rössler, Xi Wang, D. Postrach, Katrin Busch, Immanuel Rode, Kay Klapproth, Nikolaus Dietlein, C. Quedenau, Wei Chen, Sascha Sauer, S. Wolf, T. Höfer, H. Rodewald   +14 more
semanticscholar   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Sequencing of BAC pools by different next generation sequencing platforms and strategies

BMC Research Notes, 2011
Background Next generation sequencing of BACs is a viable option for deciphering the sequence of even large and highly repetitive genomes. In order to optimize this strategy, we examined the influence of read length on the quality of Roche/454 sequence ...
Scholz Uwe, Petzold Andreas, Felder Marius, Groth Marco, Schmutzer Thomas, Schulte Daniela, Ariyadasa Ruvini, Steuernagel Burkhard, Taudien Stefan, Mayer Klaus FX, Stein Nils, Platzer Matthias   +11 more
doaj   +1 more source

Karyotypes and COI Gene Sequences of Chironomus agilis2, Ch. balatonicus, and Camptochironomus tentans (Diptera, Chironomidae) from Kurchatskoe Lake, Tyumen Region, Russia

Diversity, 2022
Chironomids can inhabit a large variety of water bodies. They contribute to the process of biological purification of water bodies, and they are a high-quality food for commercial fish.
Viktor Bolshakov, Ekaterina Movergoz, Vitaly Stolbov   +2 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Sustainable tourism and green space: exploring how green spaces and natural attractions contribute to local tourism economies and revenue generation in Gauteng province

Discover Sustainability
Green spaces and natural attractions are critical assets in promoting sustainable tourism, particularly in ecologically diverse regions such as South Africa.
Enioluwa Jonathan Ijatuyi, Kowiyou Yessoufou, Hosea Olayiwola Patrick   +2 more
doaj   +1 more source

Optimization of Natural Deep Eutectic Solvent-Assisted Extraction of Rosmarinic Acid from Thunbergia laurifolia Lindl. and Evaluation of Antioxidant Activity

Molecules
Thunbergia laurifolia Lindl. is a plant known for its promising biological activity, including antioxidant and anti-inflammatory activities, and a rich source of rosmarinic acid (RA). The extraction of T.
Krittima Kriengsaksri, Wisuwat Thongphichai, Tamonwan Uttarawichien, Jasadakorn Khoochonthara, Pasarapa Towiwat, Suchada Sukrong   +5 more
doaj   +1 more source