Results 11 to 20 of about 106 (103)
S-Barrelled Topological Vector Spaces* [PDF]
Canadian Mathematical Bulletin, 1978 N. Bourbaki [1] was the first to introduce the class of locally convex topological vector spaces called “espaces tonnelés” or “barrelled spaces.” These spaces have some of the important properties of Banach spaces and Fréchet spaces. Indeed, a generalized Banach-Steinhaus theorem is valid for them, although barrelled spaces are not necessarily ...
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PRED-TMBB: a web server for predicting the topology of -barrel outer membrane proteins [PDF]
Nucleic Acids Research, 2004 The beta-barrel outer membrane proteins constitute one of the two known structural classes of membrane proteins. Whereas there are several different web-based predictors for alpha-helical membrane proteins, currently there is no freely available prediction method for beta-barrel membrane proteins, at least with an acceptable level of accuracy.
Pantelis G. Bagos +3 more
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PRED-TMBB2: improved topology prediction and detection of beta-barrel outer membrane proteins [PDF]
Bioinformatics, 2016 Abstract Motivation The PRED-TMBB method is based on Hidden Markov Models and is capable of predicting the topology of beta-barrel outer membrane proteins and discriminate them from water-soluble ones. Here, we present an updated version of the method, PRED-TMBB2, with several newly developed features
Konstantinos D. Tsirigos +2 more
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The predicted secondary structure of the G-type glutamineamidotransferase is compatible with TEM-barrel topology [PDF]
"Protein Engineering, Design and Selection", 1995 Glutamine amidotransferase (GAT) subunits or domains catalyze an important partial reaction in many complex biosynthetic reactions. The structure of one member of the F-type GATs is known, but the structure of the unrelated G-type is still unknown. Because many protein sequences are available for anthranilate synthase component II (product of the trpG ...
Niermann T, Kirschner K
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Inclusion of dyad-repeat pattern improves topology prediction of transmembrane β-barrel proteins [PDF]
Bioinformatics, 2016 Abstract Summary: Accurate topology prediction of transmembrane β-barrels is still an open question. Here, we present BOCTOPUS2, an improved topology prediction method for transmembrane β-barrels that can also identify the barrel domain, predict the topology and identify the orientation of residues in transmembrane β-strands.
Sikander Hayat +4 more
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Barrelled Linearly Topologized Modules Over a Discrete Valuation Ring
Journal of Mathematics Research, 2020 In this paper barrelled linearly topologized modules over an arbitrary discrete valuation ring are introduced. A general form of the Banach-Steinhaus theorem for continuous linear mappings on barrelled linearly topologized modules is established and some consequences of it are derived.
Dinamérico P. Pombo Jr +1 more
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Local and non‐local topological information in the denatured state ensemble of a β‐barrel protein [PDF]
Protein Science, 2018 AbstractThe folding of predominantly β‐sheet proteins is complicated by the presence of a large number of non‐local interactions in their native states, which increase the ruggedness of their folding energy landscapes. However, forming non‐local contacts early in folding or even in the unfolded state can smooth the energy landscape and facilitate ...
Abhay K. Thakur +2 more
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Evaluation of methods for predicting the topology of β-barrel outer membrane proteins and a consensus prediction method [PDF]
BMC Bioinformatics, 2005 Abstract Background Prediction of the transmembrane strands and topology of β-barrel outer membrane proteins is of interest in current bioinformatics research. Several methods have been applied so far for this task, utilizing different algorithmic techniques and a number of freely available predictors ...
Pantelis G. Bagos +2 more
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Journal of Molecular Biology, 2021 TransMembrane β-Barrel (TMBB) proteins located in the outer membranes of Gram-negative bacteria are crucial for many important biological processes and primary candidates as drug targets. Structure determination of TMBB proteins is challenging and hence computational methods devised for the analysis of TMBB proteins are important for complementing ...
Madeo G. +3 more
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Advanced Functional Materials, EarlyView.Oligomerizing Pluronic triblock copolymers provides a processing strategy for tuning the mechanical properties and stimuli‐responsive behaviors of micellar hydrogels. Varying oligomer fraction produces hydrogels spanning brittle to highly extensible responses; maintaining micellar architectures enables cooling‐induced reverse thermal shape memory and ...
Gourav Kumbhojkar +8 more
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