Results 111 to 120 of about 13,899,917 (351)
Cellular Physiology and Biochemistry, 2018 Background/Aims: Short-chain fatty acids (SCFAs) are the major energy resources of intestinal epithelial cells. It has been reported that SCFAs can repair the dysfunction of intestinal barrier, however, the underlying mechanisms are still not fully ...
Yanhai Feng +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Cigarette smoking alters intestinal barrier function and Peyer's Patch composition [PDF]
, 2011 Smokers have a two-fold increased risk to develop Crohn’s disease (CD). However, little is known about the mechanisms through which smoking affects CD pathogenesis. Interestingly, the Peyer’s patches in the terminal ileum are the sites where the first CD
Bracke, Ken +6 more
core
Subbarrier fusion of carbon isotopes: from resonance structure to fusion oscillations
, 2014 At energies below the Coulomb barrier, the fusion excitation function for the $^{12}$C+$^{12}$C system shows prominent fine structures, whereas that for the $^{12}$C+$^{13}$C system behaves more smoothly as a function of energy. We demonstrate that these
Hagino, K., Rowley, N.
core +3 more sources
Fluids and Barriers of the CNS, 2018 Receptor-mediated transcytosis is one of the major routes for drug delivery of large molecules into the brain. The aim of this study was to develop a novel model of the human blood–brain barrier (BBB) in a high-throughput microfluidic device.
Nienke R. Wevers +13 more
semanticscholar +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Schottky barriers at metal-finite semiconducting carbon nanotube interfaces
, 2003 Electronic properties of metal-finite semiconducting carbon nanotube interfaces are studied as a function of the nanotube length using a self-consistent tight-binding theory.
Ratner, Mark A., Xue, Yongqiang
core +1 more source
American Journal of Physiology - Gastrointestinal and Liver Physiology, 2019 A reduction in intestinal barrier function is currently believed to play an important role in pathogenesis of many diseases, as it facilitates passage of injurious factors such as lipopolysaccharide, peptidoglycan, whole bacteria, and other toxins to ...
M. Camilleri +5 more
semanticscholar +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source