Results 91 to 100 of about 6,511,959 (301)

Advanced Monte Carlo methods for barrier and related exotic options [PDF]

In this work, we present advanced Monte Carlo techniques applied to the pricing of barrier options and other related exotic contracts. It covers in particular the Brownian bridge approaches, the barrier shifting techniques (BAST) and their extensions as ...
Emmanuel Gobet
core  

The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression [PDF]

, 2009
The gastrointestinal tract represents the first barrier against food contaminants as well as the first target for these toxicants. Deoxynivalenol (DON) is a mycotoxin that commonly contaminates cereals and causes various toxicological effects.
Nougayrède, Jean-Philippe, Oswald, Isabelle P, Moreno, Carolina, Marin, Daniela E., Loureiro-Bracarense, Ana-Paula, Ferrier, Laurent, Oswald, Isabelle P., Pinton, Philippe, Del Rio, Juan-Carlos, Kolf-Clauw, Martine, Bracarense, Ana-Paula   +10 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Vulnerability of macroalgae of the Great Barrier Reef to climate change [PDF]

, 2007
Assessing the vulnerability of benthic macroalgae is complicated by the fact that the taxon ‘algae’ is an unnatural (and, some suggest, outdated) grouping that encompasses several distinct and diverse evolutionary lines. Adl et al.3 suggest that ‘algae’
Smith, J.E., Lotze, H.K., Smith, J., McCook, L.J., Larkum, A. W. D., Diaz-Pulido, G., Schaffelke, B., Raven, J.A., Larkum, A.W.D., Lotze, H. K., McCook, L. J., Raven, J. A., Steneck, R. S., Steneck, R.S.   +13 more
core  

Chapter 23: Climate change and Great Barrier Reef: industries and communities [PDF]

, 2007
Climate change is driving shifts in environmental conditions that, together with other human pressures, are impacting the Great Barrier Reef (GBR). Individuals, communities, and industries in the GBR catchment depend directly or indirectly on the GBR ...
Vella, K., Kelly, G., Innes, J., Fenton, M.   +3 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Barrier Function of Gastric Mucus.

The Keio Journal of Medicine, 1999
A viscoelastic mucus gel layer covers the gastric mucosa in a continuous sheet. The functions of the mucus gel have been one of the least studied aspects of gastric barrier function. Although the role of gastric mucus in providing physical protection against ingested particles, and preventing contact between digestive enzymes such as pepsin and the ...
openaire   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Lactobacillus Re-Engineers Gut Microbiota to Overcome E. coli Colonization Resistance in Mice

Veterinary Sciences
The intestinal health and functionality of animals play pivotal roles in nutrient digestion and absorption, as well as in maintaining defense against pathogenic invasions.
Jianlei Jia, Pengjia Bao, Qinran Yu, Ning Li, Hao Ren, Qian Chen, Ping Yan   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source