Results 111 to 120 of about 3,618,266 (313)

Jesus’ Principles of Breaking Barriers: A Reflection on John 4:3-42 [PDF]

open access: yes, 2018
This paper investigates Jesus’ Principles of Breaking Barriers: A Reflection on John 4:3-42 as a pivot and principle for breaking barriers from biblical perspective.
Ubong E., E. Y. O.
core  

Spin glass overlap barriers in three and four dimensions

open access: yes, 2000
For the Edwards-Anderson Ising spin-glass model in three and four dimensions (3d and 4d) we have performed high statistics Monte Carlo calculations of those free-energy barriers $F^q_B$ which are visible in the probability density $P_J(q)$ of the Parisi ...
Alain Billoire   +36 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

The Quality Control of Micro- and Nanomedicines: Compliance with Regulatory Guidelines

open access: yesPharmaceutical Fronts
Carrier-based micro- and nanomedicines, such as microspheres, liposomes, and micelles, offer enhanced benefits over traditional medications, including improved bioavailability, targeted delivery, and reduced toxicity.
Lu Li, Wei Wu, Jian Le, Yi Lu
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

Blending with Poly(l‑lactic acid) Improves the Printability of Poly(l‑lactide-co-caprolactone) and Enhances the Potential Application in Cartilage Tissue Engineering

open access: yesACS Omega, 2021
Ruiping Duan   +9 more
doaj   +1 more source

Who are wine tourists? An empirical investigation of segments in Serbian wine tourism [PDF]

open access: yesEkonomika Poljoprivrede (1979), 2017
This paper aims to investigate who are the wine tourists in Serbia. The research was conducted by using a survey method. Two profile questions were used aimed to identify segments: 'Do you consume wine?' and 'Have you ever visited some winery in Serbia'?
Sekulić Dejan   +2 more
doaj  

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