Results 71 to 80 of about 41,331 (231)

The Influence of Supplemental Dietary Linoleic Acid on Skeletal Muscle Contractile Function in a Rodent Model of Barth Syndrome

Frontiers in Physiology, 2021
Barth syndrome is a rare and incurable X-linked (male-specific) genetic disease that affects the protein tafazzin (Taz). Taz is an important enzyme responsible for synthesizing biologically relevant cardiolipin (for heart and skeletal muscle, cardiolipin
Mario Elkes, Martin Andonovski, Daislyn Vidal, Madison Farago, Ryan Modafferi, Steven M. Claypool, Paul J. LeBlanc   +6 more
doaj   +1 more source

Good Public Theology is Twilight Theology. A Constructive Deconstruction of Public Theology

International Journal of Systematic Theology, EarlyView.
Abstract The article outlines the basic features of a good public theology that is inspired by Paul’s description of the situation of the church and Christians: ‘The night has passed, the day is not far distant’ (Rom 13:12). In his analysis of the present, the author identifies eight specific challenges of contemporary culture – challenges that have so
Günter Thomas
wiley   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Successful management of Barth syndrome: a systematic review highlighting the importance of a flexible and multidisciplinary approach

Journal of Multidisciplinary Healthcare, 2015
Stacey Reynolds Department of Occupational Therapy, Virginia Commonwealth University, Richmond, VA, USA Abstract: This review describes and summarizes the available evidence related to the treatment and management of Barth syndrome.
Reynolds S
doaj  

Development and Validation of the Brief Inventory of Treatment Expectations in Chronic Pain (BITEC)

European Journal of Pain, Volume 30, Issue 2, February 2026.
ABSTRACT Background Expectations shape therapeutic outcomes, yet their systematic assessment remains limited in clinical and research settings. To address this gap, we developed and validated the Brief Instrument for the Assessment of Treatment Expectations in Chronic Pain (BITEC) using Item Response Theory. Methods The study comprised four phases. (I)
Wolnei Caumo, Bárbara Regina França, Jaira Ehlers, Stela Maris de Jezus Castro, Rogério Boff Borges, Vania Naomi Hirakata, Graziele Borges Bueno, Iraci LS da Torres, Felipe Fregni   +8 more
wiley   +1 more source

Effects of Clostridium perfringens iota toxin in the small intestine of mice [PDF]

, 2017
Iota toxin is a binary toxin solely produced by Clostridium perfringens type E strains, and is structurally related to CDT from C. difficile and CST from C. spiroforme.
Bruzzone, Octavio Augusto, Cangelosi, Adriana, Dailoff, Gabriela Cecilia, Díaz Carrasco, Juan María, Fernandez Miyakawa, Mariano Enrique, Geoghegan, Patricia, Leiva, Carlos Leónidas, Redondo, Enzo Alejandro, Redondo, Leandro Martin   +8 more
core   +1 more source

The Creation of a Weight of Evidence Scoring Database for Risk Factors for Adverse Impacts to Birth Outcomes Using Expert Elicitation

Birth Defects Research, Volume 118, Issue 1, January 2026.
ABSTRACT Background Adverse birth outcomes are important public health measures and account for a substantial public health burden. There is considerable diversity of these health endpoints, as well as in the many factors suspected or recognized to increase their risk.
Paul J. Villeneuve, Ann Aschengrau, Michelle L. Bell, Yang Cao, Mark Elwood, Guy Eslick, Shelley Harris, Leeka Kheifets, Babak Khoshnood, Robert Norman, Nelson Pace, Johan Reutfors, Jeremy M. Schraw, Jose R. Suarez‐Lopez, Gunnar Toft, R. Douglas Wilson, Christopher R. Kirman, Tyler Carneal, Sean M. Hays   +18 more
wiley   +1 more source

Human trifunctional protein alpha links cardiolipin remodeling to beta-oxidation. [PDF]

PLoS ONE, 2012
Cardiolipin (CL) is a mitochondrial membrane phospholipid which plays a key role in apoptosis and supports mitochondrial respiratory chain complexes involved in the generation of ATP.
William A Taylor, Edgard M Mejia, Ryan W Mitchell, Patrick C Choy, Genevieve C Sparagna, Grant M Hatch   +5 more
doaj   +1 more source

The impact of female obesity on the outcome of fertility treatment [PDF]

, 2010
Peer reviewedPublisher ...
Abha Maheshwari, Ayyad, Balen, Balen, Bellver, Bellver, Bellver, Bergh, Brannian, Clark, Diamanti-Kandarakis, Dodson, Ehrmann, Gil-Campos, Hamilton-Fairley, Hollmann, Hossain, Huber-Buchholz, Imani, Imani, Jungheim, Kiddy, Koloszar, Law, Li, Maheshwari, Metwally, Metwally, Metwally, Moran, Moschos, Mulders, Nohr, Ogden, Orvieto, Palomba, Panidis, Pasquali, Prentice, Rich-Edwards, Shilpi Pandey, Siladitya Bhattacharya, Suruchi Pandey, Tang, The, Tsagareli, Van, Wadden, Wang, Wattanakumtornkul, Wise, Zaadstra, Zachariah, Zhang   +53 more
core   +3 more sources

Safety, Pharmacokinetics, and Pharmacodynamics of Osivelotor for Sickle Cell Disease: First‐in‐Human Studies in Healthy Participants and Patients

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 120-130, January 2026.
The investigational agent osivelotor, a small molecule hemoglobin (Hb) modifier in development for the treatment of sickle cell disease (SCD), acts by increasing Hb‐oxygen affinity and inhibiting the polymerization of sickle Hb. We report safety, pharmacokinetic (PK), and pharmacodynamic (PD) data from the first two phase 1 clinical trials of ...
Eleanor A. Lisbon, R. Clark Brown, Andrew Redfern, Ken Duchin, Aline Barth, Erika S. Roberts, Polo Gaputan, Kobina Dufu, Arthur Lo, Mira Patel Pochron, David R. Archer, Wai Chin, Karena Kong, Carla B. Washington, Adeyemi Adenola, Eric I. Zimmerman   +15 more
wiley   +1 more source