Results 21 to 30 of about 32,167,916 (377)
Ciliary force-responsive striated fibers promote basal body connections and cortical interactions. [PDF]
J Cell Biol, 2020 Soh et al. study the organization of Tetrahymena ciliary arrays. Basal body–associated striated fibers organize motile cilia by promoting basal body orientation, reorientation, and resistance to ciliary forces.
Soh AWJ +6 more
europepmc +2 more sources
A specific basal body linker protein provides the connection function for basal body inheritance in trypanosomes. [PDF]
Proc Natl Acad Sci U S A, 2021 Significance Centriole/basal body (BB) connections involve two concepts: a tether and a linker. Studies have revealed essential components of the tether, while linker components remain largely unknown. Here, we describe BBLP, a trypanosome protein that is a cytoskeletal component of the linker, localizing between the BB and pro-BB throughout ...
Lai DH +4 more
europepmc +5 more sources
Journal of Developmental Biology, 2022 The development of multicellular organisms requires a tightly coordinated network of cellular processes and intercellular signalling. For more than 20 years, it has been known that primary cilia are deeply involved in the mediation of intercellular ...
Thorsten Pfirrmann, Christoph Gerhardt
doaj +1 more source
Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission. [PDF]
Life Sci Alliance, 2019 This comprehensive study describes the key role and real-time dynamics of Plasmodium kinesin-8B in microtubule-based basal body and axoneme assembly during flagellum (male gamete) formation and parasite transmission.
Zeeshan M +12 more
europepmc +2 more sources
Tetrahymena basal bodies [PDF]
Cilia, 2015 Tetrahymena thermophila is a ciliate with hundreds of cilia primarily used for cellular motility. These cells propel themselves by generating hydrodynamic forces through coordinated ciliary beating. The coordination of cilia is ensured by the polarized organization of basal bodies (BBs), which exhibit remarkable structural and molecular conservation ...
Brian A. Bayless +2 more
openaire +3 more sources
Parental centrioles are dispensable for deuterosome formation and function during basal body amplification. [PDF]
EMBO Rep, 2019 Mammalian epithelial cells use a pair of parental centrioles and numerous deuterosomes as platforms for efficient basal body production during multiciliogenesis. How deuterosomes form and function, however, remain controversial.
Zhao H +6 more
europepmc +2 more sources
Cilia, 2015 Xenopus has been one of the earliest and most important vertebrate model organisms for investigating the role and structure of basal bodies. Early transmission electron microscopy studies in Xenopus revealed the fine structures of Xenopus basal bodies and their accessory structures.
Brian J. Mitchell, Siwei Zhang
openaire +2 more sources
Tetrahymena Poc5 is a transient basal body component that is important for basal body maturation. [PDF]
J Cell Sci, 2020 ABSTRACT Basal bodies (BBs) are microtubule-based organelles that act as a template for and stabilize cilia at the cell surface. Centrins ubiquitously associate with BBs and function in BB assembly, maturation and stability. Human POC5 (hPOC5) is a highly conserved centrin-binding protein that binds centrins through Sfi1p-like repeats ...
Heydeck W +7 more
europepmc +4 more sources
Microtubule Organizing Centers Contain Testis-Specific γ-TuRC Proteins in Spermatids of Drosophila
Frontiers in Cell and Developmental Biology, 2021 Microtubule nucleation in eukaryotes is primarily promoted by γ-tubulin and the evolutionary conserved protein complex, γ-Tubulin Ring Complex (γ-TuRC).
Elham Alzyoud +6 more
doaj +1 more source
bioRxiv, 2020 Intraflagellar transport (IFT) is essential for construction and maintenance of cilia. IFT proteins concentrate at the basal body, where they are thought to assemble into trains and bind cargoes for transport.
J. V. Hibbard +3 more
semanticscholar +1 more source