Results 41 to 50 of about 32,167,916 (377)

Disruption of the basal body protein POC1B results in autosomal-recessive cone-rod dystrophy [PDF]

open access: yes, 2014
Exome sequencing revealed a homozygous missense mutation (c.317C>G [p.Arg106Pro]) in POC1B, encoding POC1 centriolar protein B, in three siblings with autosomal-recessive cone dystrophy or cone-rod dystrophy and compound-heterozygous POC1B mutations (c ...
Arts, Heleen H   +17 more
core   +2 more sources

Basal bodies across eukaryotes series: basal bodies in the freshwater planarian Schmidtea mediterranea [PDF]

open access: yesCilia, 2016
The freshwater planarian Schmidtea mediterranea has recently emerged as a valuable model system to study basal bodies (BBs) and cilia. Planarians are free-living flatworms that use cilia beating at the surface of their ventral epidermis for gliding along substrates. The ventral epidermis is composed of multiciliated cells (MCCs) that are similar to the
Azimzadeh, Juliette, Basquin, Cyril
openaire   +3 more sources

Sfr1, a Tetrahymena thermophila Sfi1 Repeat Protein, Modulates the Production of Cortical Row Basal Bodies

open access: yesmSphere, 2016
Basal bodies are essential microtubule-based structures that template, anchor, and orient cilia at the cell surface. Cilia act primarily in the generation of directional fluid flow and sensory reception, both of which are utilized for a broad spectrum of
Westley Heydeck   +4 more
doaj   +1 more source

BBS4 is required for intraflagellar transport coordination and basal body number in mammalian olfactory cilia.

open access: yesJ Cell Sci, 2019
Bardet–Beidl syndrome (BBS) manifests from genetic mutations encoding for one or more BBS proteins. BBS4 loss impacts olfactory ciliation and odor detection, yet the cellular mechanisms remain unclear.
Uytingco CR   +9 more
europepmc   +2 more sources

Distribution of interstitial stem cells in Hydra [PDF]

open access: yes, 1979
The distribution of interstitial stem cells along the Hydra body column was determined using a simplified cloning assay. The assay measures stem cells as clone-forming units (CFU) in aggregates of nitrogen mustard inactivated Hydra tissue.
Bode   +16 more
core   +2 more sources

Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in Drosophila

open access: yeseLife, 2019
Cilia and flagella are conserved eukaryotic organelles essential for cellular signaling and motility. Cilia dysfunctions cause life-threatening ciliopathies, many of which are due to defects in the transition zone (TZ), a complex structure of the ciliary
Jean-André Lapart   +10 more
doaj   +1 more source

Prawn Shell Chitosan Has Anti-Obesogenic Properties, Influencing Both Nutrient Digestibility and Microbial Populations in a Pig Model [PDF]

open access: yes, 2015
This study was supported financially (Grant-Aid Agreement No. MFFRI/07/01) under the Sea Change Strategy with the support of the Marine Institute and the Department of Agriculture, Food and the Marine, funded under the National Development Plan 2007 ...
Egan, Aine M.   +3 more
core   +1 more source

Noncanonical Biogenesis of Centrioles and Basal Bodies [PDF]

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 2017
Centrioles and basal bodies (CBBs) organize centrosomes and cilia within eukaryotic cells. These organelles are composed of microtubules and hundreds of proteins performing multiple functions such as signaling, cytoskeleton remodeling, and cell motility.
Nabais, Catarina   +2 more
openaire   +3 more sources

New Tetrahymena basal body protein components identify basal body domain structure [PDF]

open access: yesThe Journal of Cell Biology, 2007
Basal bodies organize the nine doublet microtubules found in cilia. Cilia are required for a variety of cellular functions, including motility and sensing stimuli. Understanding this biochemically complex organelle requires an inventory of the molecular components and the contribution each makes to the overall structure. We define a basal body proteome
Chandra L. Kilburn   +7 more
openaire   +5 more sources

Cellular Mechanisms of Ciliary Length Control

open access: yesCells, 2016
Cilia and flagella are evolutionarily conserved, membrane-bound, microtubule-based organelles on the surface of most eukaryotic cells. They play important roles in coordinating a variety of signaling pathways during growth, development, cell mobility ...
Jacob Keeling   +2 more
doaj   +1 more source

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