Synaptic Potentiation in Hippocampus by eEF2K Inhibitor A484954
ABSTRACT An important mechanism controlling protein synthesis is through phosphorylation of the eukaryotic elongation factor 2 (eEF2) by its kinase eEF2K. Hyperphosphorylation of eEF2 is linked to many neuronal diseases characterized by cognitive impairments.
Qian Yang +6 more
wiley +1 more source
The basal forebrain cholinergic system
De centrale vraagstellingen in dit proefschrift zijn hoe de verbindingen van cholinerge systeem zijn georganiseerd en hoe de anatomie van de cholinerge projecties beïnvloed wordt door veroudering en door partiële degeneratie van de cholinerge neuronen.
openaire +1 more source
miR‐146a/b‐5p‐IRAK1‐NF‐κB Axis Regulates Unexplained Recurrent Spontaneous Abortion
ABSTRACT Unexplained recurrent spontaneous abortion (URSA) remains a prevalent obstetric issue, the underlying causes of which are still not fully understood. MicroRNAs (miRNAs) have the potential to influence URSA through their regulation of gene expression.
Fengping He +7 more
wiley +1 more source
The basal forebrain-DMN/solv cholinergic projection mediates the attenuation of brain injury after cardiopulmonary resuscitation. [PDF]
Xia S +9 more
europepmc +1 more source
This study reports novel compound heterozygous LAMA1 variants in two siblings with Poretti‐Boltshauser syndrome presenting with cerebral hypomyelination. It provides the first clinical evidence linking LAMA1 to CNS dysmyelination, expanding the phenotypic spectrum and offering mechanistic insights into this rare association. ABSTRACT Background Poretti‐
Si Huang +8 more
wiley +1 more source
Cholinergic basal forebrain degeneration in isolated REM sleep behaviour disorder. [PDF]
Kim R +10 more
europepmc +1 more source
Simultaneous Detection of GABA and Glycine Using MEGA‐PRESS With TE Optimization at 3T
ABSTRACT Purpose To achieve the simultaneous acquisition of gamma‐aminobutyric acid (GABA) and glycine (Gly) using a MEGA‐PRESS sequence with an optimized TE at 3T. Methods MEGA‐PRESS simulations were performed at TEs 60‐88 ms to determine the optimal TE for Gly detection with minimal myo‐Inositol (mI) overlap and maximal GABA detection sensitivity ...
Justin R. Singer, Kimberly L. Chan
wiley +1 more source
Surgical treatment of an intracranial Cryptococcus granuloma in a cat
Summary A 4‐year‐old, female, neutered, domestic short‐haired cat presented with an acute onset of progressive compulsive pacing and obtundation. General physical examination revealed a crusty nasal discharge, with neurological examination showing a forebrain localisation.
Guido Bertoldi +4 more
wiley +1 more source
Selective attention to auditory and visual modalities converges onto noncholinergic basal forebrain neurons. [PDF]
Liu SW, Lin SC.
europepmc +1 more source
Anatomical Description of the Main Gyri and Sulci of the Telencephalon of Alouatta belzebul
ABSTRACT The Alouatta belzebul is a species of howler monkey, of the Atelidae family and genus Alouatta. It is endemic in Brazil and has a separate geographic distribution, with two populations occurring: in the Amazon and in the Atlantic Forest on the coast of Northeast Brazil. The species is classified as ‘vulnerable’, and this is mainly justified by
Dayane Kelly Sabec Pereira +4 more
wiley +1 more source

