Results 161 to 170 of about 87,758 (253)
Vulnerability of long-range inputome of basal forebrain in normal aging mice. [PDF]
Sun T +5 more
europepmc +1 more source
Abstract INTRODUCTION The locus coeruleus (LC) is among the first sites of tau pathology in Alzheimer's disease (AD) and may seed neocortical tau. METHODS We used longitudinal neuromelanin‐sensitive MRI to assess LC integrity in vivo in a cohort of cognitively unimpaired older adults with familial risk of AD in relation to tau and amyloid positron ...
Alfie Wearn +14 more
wiley +1 more source
Basal forebrain cholinergic input mediates adaptive attention allocation to enhance olfactory discrimination. [PDF]
Garg R, Qiu Q, Yu CR.
europepmc +1 more source
Bioimaging of the sense organs and brain of fishes and reptiles. Left panel: 3D reconstruction of the head and brain of the deep‐sea viperfish Chauliodus sloani following diceCT. Right panel: A 3D reconstruction of a 70‐day‐old embryo head of the bearded dragon Pogona vitticeps following diceCT, showing the position of the segmented brain within the ...
Shaun P. Collin +9 more
wiley +1 more source
Single-nucleus analysis reveals oxidative stress in Down syndrome basal forebrain neurons at birth. [PDF]
West NR +11 more
europepmc +1 more source
Altered Brain Structure in an ATRX‐Deficient Mouse Model of Autism Spectrum Disorder
ABSTRACT Mutations in the ATRX gene are a primary cause of alpha‐thalassemia intellectual disability X‐linked (ATRX) syndrome, which is characterized by intellectual disability, autism, and a range of brain structural abnormalities, including microcephaly.
Katherine Quesnel +3 more
wiley +1 more source
Cholinotrophic basal forebrain connectome dysfunction in Down syndrome with and without dementia. [PDF]
Moreno-Rodriguez M +4 more
europepmc +1 more source
DNA Methylation‐Regulated ZDHHC24 Exacerbates the Risk of Intracranial Aneurysms
Multimodal Mendelian randomization integrating multi‐omics datasets pinpointed four DNA‐methylation loci that act in concert with the palmitoylation gene ZDHHC24 to modulate intracranial aneurysm risk, shedding new light on the molecular etiology of IA susceptibility and highlighting potential therapeutic targets.
Hao Yuan +6 more
wiley +1 more source

