Most Ventral Pallidal Cholinergic Neurons Are Bursting Basal Forebrain Cholinergic Neurons with Mesocorticolimbic Connectivity. [PDF]
Schlingloff D +6 more
europepmc +1 more source
Narcolepsy and rapid eye movement sleep
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini +4 more
wiley +1 more source
Lower cerebral blood flow but not cerebrovascular response in elastin haploinsufficient mice
Abstract Elastin insufficiency is associated with structural differences in the large elastic arteries and cerebral artery dysfunction. However, previous studies have not assessed potential sex differences in cerebrovascular function. We measured cerebral blood flow (CBF) using arterial spin labeling MRI at rest and in response to hypercapnia challenge
Abigail E. Cullen +15 more
wiley +1 more source
Cholinergic basal forebrain degeneration in isolated REM sleep behaviour disorder. [PDF]
Kim R +10 more
europepmc +1 more source
Mitochondrial control of ciliary gene expression and structure in striatal neurons
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen +5 more
wiley +1 more source
Targeting NDUFS8 in basal forebrain ameliorates cognitive decline related to chronic cerebral hypoperfusion. [PDF]
Qu Y +20 more
europepmc +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
Adult zebrafish radial glia quiescence is controlled by at least four mechanisms: Notch3, BMP‐Id1, Nr2f1b and Midkine‐a. We propose these act as partially redundant inputs, biased along the antero‐posterior axis that set quiescence depth. ABSTRACT The zebrafish telencephalon is an excellent model for adult neurogenesis under physiological and ...
Mathilde Hoareau +2 more
wiley +1 more source
Glutamatergic projection neurons in the basal forebrain underlie learned olfactory associational valence assignments. [PDF]
Chin PS +6 more
europepmc +1 more source
ELE: Estimating tissue‐specific long noncoding RNA gene essentiality using graph neural networks
Abstract A gene is essential if its loss of function results in lethality, reduced fitness, or disease. Essential genes have attracted increasing attention due to their vital functions in biological systems. Many efforts have been made to find essential protein‐coding genes.
Wan‐Ting Shi +3 more
wiley +1 more source

