Results 1 to 10 of about 234,657 (299)

The genetic landscape of basal ganglia and implications for common brain disorders. [PDF]

Nat Commun
The basal ganglia are subcortical brain structures involved in motor control, cognition, and emotion regulation. We conducted univariate and multivariate genome-wide association analyses (GWAS) to explore the genetic architecture of basal ganglia volumes
Bahrami S, Nordengen K, Rokicki J, Shadrin AA, Rahman Z, Smeland OB, Jaholkowski PP, Parker N, Parekh P, O'Connell KS, Elvsåshagen T, Toft M, Djurovic S, Dale AM, Westlye LT, Kaufmann T, Andreassen OA.   +16 more
europepmc   +4 more sources

Integration of navigation and action selection functionalities in a computational model of cortico-basal ganglia-thalamo-cortical loops [PDF]

Adaptive Behavior 13 (2005) 115-130, 2006
This article describes a biomimetic control architecture affording an animat both action selection and navigation functionalities. It satisfies the survival constraint of an artificial metabolism and supports several complementary navigation strategies.
Berthoz, Alain, Filliat, David, Girard, Benoît, Guillot, Agnès, Meyer, Jean-Arcady   +4 more
arxiv   +4 more sources

Role of the Basal Ganglia in Balance Control [PDF]

Neural Plasticity, 2005
In this review paper, we summarize the important contributions of the basal ganglia to the regulation of postural control. After a brief overview of basal ganglia circuitries, the emphasis is on clinical observations in patients with focal lesions in ...
Jasper E. Visser, Bastiaan R. Bloem
doaj   +5 more sources

Saccade learning with concurrent cortical and subcortical basal ganglia loops [PDF]

arXiv, 2013
The Basal Ganglia is a central structure involved in multiple cortical and subcortical loops. Some of these loops are believed to be responsible for saccade target selection. We study here how the very specific structural relationships of these saccadic loops can affect the ability of learning spatial and feature-based tasks.
Girard, Benoît, N'Guyen, Steve, Thurat, Charles   +2 more
arxiv   +6 more sources

The Basal Ganglia and Motor Control [PDF]

Neural Plasticity, 2003
This paper briefly reviews the functional anatomy of the basal ganglia and their relationships with the thalamocortical system. The basal ganglia, including the striatum, pallidum, subthalamic nucleus, and substantia nigra, are involved in a number of ...
Henk J. Groenewegen
doaj   +5 more sources

Contribution of basal ganglia activity to REM sleep disorder in Parkinson's disease. [PDF]

J Neurol Neurosurg Psychiatry
Background: Rapid eye movement (REM) sleep behaviour disorder (RBD) is one of the most common sleep problems and represents a key prodromal marker in Parkinson’s disease (PD).
Yin Z, Yuan T, Yang A, Xu Y, Zhu G, An Q, Ma R, Gan Y, Shi L, Bai Y, Zhang N, Wang C, Jiang Y, Meng F, Neumann WJ, Tan H, Zhang JG.   +16 more
europepmc   +3 more sources

Germinoma of basal ganglia. [PDF]

Radiol Case Rep
Basal ganglia germinomas (BGGs) are rare lesions. Because of the atypical features of early-stage clinical symptoms and imaging characteristics, BGGs are easily misdiagnosed with non-tumorous conditions.
Tuan HX, Huyen NT, Son ND, Trung NV, Anh NH, Hung ND, Duc NM.   +6 more
europepmc   +2 more sources

Ropinirole Cotreatment Prevents Perivascular Glial Recruitment in a Rat Model of L-DOPA-Induced Dyskinesia

Cells, 2023
Dopamine replacement therapy for Parkinson’s disease is achieved using L-DOPA or dopamine D2/3 agonists, such as ropinirole. Here, we compare the effects of L-DOPA and ropinirole, alone or in combination, on patterns of glial and microvascular reactivity
Osama F. Elabi, Elena Espa, Katrine Skovgård, Silvia Fanni, Maria Angela Cenci   +4 more
doaj   +1 more source

Motor symptom asymmetry predicts non-motor outcome and quality of life following STN DBS in Parkinson's disease

Scientific Reports, 2022
Risk factors for long-term non-motor symptoms and quality of life following subthalamic nucleus deep brain stimulation (STN DBS) have not yet been fully identified.
Philippe Voruz, Jordan Pierce, Kévin Ahrweiller, Claire Haegelen, Paul Sauleau, Sophie Drapier, Dominique Drapier, Marc Vérin, Julie Péron   +8 more
doaj   +1 more source

APOE ε4 allele, along with G206D-PSEN1 mutation, alters mitochondrial networks and their degradation in Alzheimer’s disease

Frontiers in Aging Neuroscience, 2023
IntroductionAlzheimer’s disease remains the most common neurodegenerative disorder, depicted mainly by memory loss and the presence in the brain of senile plaques and neurofibrillary tangles.
Irene Costa-Laparra, Elena Juárez-Escoto, Elena Juárez-Escoto, Carlos Vicario, Carlos Vicario, Rosario Moratalla, Rosario Moratalla, Patricia García-Sanz, Patricia García-Sanz   +8 more
doaj   +1 more source