Dissociation of metabolic and hemodynamic levodopa responses in the 6-hydroxydopamine rat model
Dissociation of vasomotor and metabolic responses to levodopa has been observed in human subjects with Parkinson's disease (PD) studied with PET and in autoradiograms from 6-hydroxydopamine (6-OHDA) rat. In both species, acute levodopa administration was
Renata P. Lerner +6 more
doaj +1 more source
Neuroimaging of Basal Ganglia in Neurometabolic Diseases in Children
Diseases primarily affecting the basal ganglia in children result in characteristic disturbances of movement and muscle tone. Both experimental and clinical evidence indicates that the basal ganglia also play a role in higher mental states.
Justyna Paprocka +3 more
doaj +1 more source
PDZD8 is not the ‘functional ortholog’ of Mmm1, it is a paralog [version 1; referees: 2 approved]
Authors of a recent paper demonstrate that, like ERMES (ER-mitochondria encounter structure) in fungal cells, PDZD8 (PDZ domain containing 8) tethers mitochondria to the ER in mammalian cells.
Jeremy G. Wideman +3 more
doaj +1 more source
A Sing-Song Way of Vocalizing: Generalization and Specificity in Language and Birdsong. [PDF]
Spoken languages such as German are extremely discrete, whereas others such as Portuguese are melodic or "sing-song" wherein identifying a word relies on what comes before and after.
Farias-Virgens, Madza +1 more
core +1 more source
The correlation between lateralization of intracerebral hemorrhage in basal ganglia and handedness [PDF]
PURPOSE: To investigate the correlation between lateralization of cerebral basal ganglia hemorrhage and handedness. METHODS: Medical records and computed tomography (CT) scans for 84 patients with primary hypertensive intracerebral hemorrhage (ICH) in ...
Yu Cui +6 more
doaj +3 more sources
White matter abnormalities in depression: A categorical and phenotypic diffusion MRI study
Mood depressive disorder is one of the most disabling chronic diseases with a high rate of everyday life disability that affects 350 million people around the world.
Julie Coloigner +6 more
doaj +1 more source
A biologically inspired computational model of the Block Copying Task [PDF]
We present in this paper a biologically inspired model of the Basal Ganglia which deals with Block Copying as a sequence learning task. By breaking a relatively complex task into simpler operations with well-defined skills, an approach which is termed as
Arnold, Michael +3 more
core
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski +13 more
wiley +1 more source
Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder characterized by widespread oligodendroglial cytoplasmic inclusions of filamentous α-synuclein, and neuronal loss in autonomic centres, basal ganglia and cerebellar ...
Violetta Refolo +11 more
doaj +1 more source
Is there an integrative center in the vertebrate brain-stem? A robotic evaluation of a model of the reticular formation viewed as an action selection device [PDF]
Neurobehavioral data from intact, decerebrate, and neonatal rats, suggests that the reticular formation provides a brainstem substrate for action selection in the vertebrate central nervous system.
Baerends, G. +15 more
core +2 more sources

