Results 51 to 60 of about 26,837,992 (363)

The correlation between lateralization of intracerebral hemorrhage in basal ganglia and handedness [PDF]

open access: yesActa Cirúrgica Brasileira, 2013
PURPOSE: To investigate the correlation between lateralization of cerebral basal ganglia hemorrhage and handedness. METHODS: Medical records and computed tomography (CT) scans for 84 patients with primary hypertensive intracerebral hemorrhage (ICH) in ...
Yu Cui   +6 more
doaj   +3 more sources

Mean-field modeling of the basal ganglia-thalamocortical system. II. Dynamics of parkinsonian oscillations [PDF]

open access: yesJ. Theor. Biol. 257:664-688 (2009), 2018
Neuronal correlates of Parkinson's disease (PD) include a slowing of the electroencephalogram (EEG) and enhanced synchrony at 3-7 and 7-30 Hz in the basal ganglia, thalamus, and cortex. This study describes the dynamics of a physiologically based mean-field model of the basal ganglia-thalamocortical system, and shows how it accounts for key ...
arxiv   +1 more source

Real-Time Recurrent Reinforcement Learning [PDF]

open access: yes, 2023
We introduce a biologically plausible RL framework for solving tasks in partially observable Markov decision processes (POMDPs). The proposed algorithm combines three integral parts: (1) A Meta-RL architecture, resembling the mammalian basal ganglia; (2) A biologically plausible reinforcement learning algorithm, exploiting temporal difference learning ...
arxiv   +1 more source

Functional segregation of basal ganglia pathways in Parkinson’s disease

open access: yesBrain : a journal of neurology, 2018
Dopamine exerts modulatory signals on cortex-basal ganglia circuits to enable flexible motor control. Parkinson's disease is characterized by a loss of dopaminergic innervation in the basal ganglia leading to complex motor and non-motor symptoms ...
W. Neumann   +9 more
semanticscholar   +1 more source

The burden of intracranial atherosclerosis on cerebral small vessel disease: A community cohort study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Exploring the prevalence and association between intracranial atherosclerosis (ICAS) and cerebral small vessel diseases (CSVD), this study delved beyond the current scope, utilising high‐resolution vessel wall MRI (HRVW‐MRI) to investigate how subtle changes in intracranial atherosclerotic features influence the various burdens of ...
Joseph Amihere Ackah   +6 more
wiley   +1 more source

Progressive Myoclonus Epilepsy: Distinctive MRI Changes in Cerebellar and Motor Networks

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive myoclonus epilepsy (PME) is a rare generalized epilepsy syndrome with a well‐characterized genetic basis. The brain networks that are affected to give rise to the distinctive symptoms of PME are less well understood. Methods Eleven individuals with PME with a confirmed genetic diagnosis and 22 controls were studied.
Jillian M. Cameron   +3 more
wiley   +1 more source

Neuropsychiatry of the basal ganglia [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 2002
This review aims to relate recent findings describing the role and neural connectivity of the basal ganglia to the clinical neuropsychiatry of basal ganglia movement disorders and to the role of basal ganglia disturbances in "psychiatric"' states. Articles relating to the relevant topics were initially collected through MEDLINE and papers relating to ...
Jordi Serra-Mestres, Howard Ring
openaire   +3 more sources

Consensus Paper: Towards a Systems-Level View of Cerebellar Function: the Interplay Between Cerebellum, Basal Ganglia, and Cortex

open access: yesCerebellum, 2016
Despite increasing evidence suggesting the cerebellum works in concert with the cortex and basal ganglia, the nature of the reciprocal interactions between these three brain regions remains unclear.
Daniele Caligiore   +17 more
semanticscholar   +1 more source

Rodent models of impulsive–compulsive behaviors in Parkinson's disease: How far have we reached?

open access: yesNeurobiology of Disease, 2015
There is increasing awareness that the medications used to treat the motor symptoms of Parkinson's disease (PD) contribute to the development of behavioral addictions, which have been clinically defined as impulsive–compulsive behaviors (ICBs).
M. Angela Cenci   +3 more
doaj  

Modeling effect of GABAergic current in a basal ganglia computational model [PDF]

open access: yesCogn. Neurodyn. 6(4), 333-341 (2012), 2013
Electrical high frequency stimulation (HFS) of deep brain regions is a method shown to be clinically effective in different types of movement and neurological disorders. In order to shed light on its mode of action a computational model of the basal ganglia network coupled the HFS as injection current into the cells of the subthalamic nucleus (STN ...
arxiv   +1 more source

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