Results 51 to 60 of about 28,372,502 (356)
Role of basal ganglia neurocircuitry in the pathology of psychiatric disorders
Psychiatry and Clinical Neurosciences, 2019 Over the last few decades, advances in human and animal‐based techniques have greatly enhanced our understanding of the neural mechanisms underlying psychiatric disorders.
Tom Macpherson, T. Hikida
semanticscholar +1 more source
A basal ganglia inspired model of action selection evaluated in a robotic survival task. [PDF]
, 2003 The basal ganglia system has been proposed as a possible neural substrate for action selection in the vertebrate brain. We describe a robotic implementation of a model of the basal ganglia and demonstrate the capacity of this system to generate adaptive ...
Cuzin, V. +4 more
core +3 more sources
Recent advances in understanding the role of the basal ganglia
F1000Research, 2019 The basal ganglia are a complex subcortical structure that is principally involved in the selection and implementation of purposeful actions in response to external and internal cues.
K. Simonyan
semanticscholar +1 more source
White matter abnormalities in depression: A categorical and phenotypic diffusion MRI study
NeuroImage: Clinical, 2019 Mood depressive disorder is one of the most disabling chronic diseases with a high rate of everyday life disability that affects 350 million people around the world.
Julie Coloigner +6 more
doaj +1 more source
A biologically inspired computational model of the Block Copying Task [PDF]
, 2003 We present in this paper a biologically inspired model of the Basal Ganglia which deals with Block Copying as a sequence learning task. By breaking a relatively complex task into simpler operations with well-defined skills, an approach which is termed as
Arnold, Michael +3 more
core
Remembering Forward: Neural Correlates of Memory and Prediction in Human Motor Adaptation [PDF]
, 2012 We used functional MR imaging (FMRI), a robotic manipulandum and systems identification techniques to examine neural correlates of predictive compensation for spring-like loads during goal-directed wrist movements in neurologically-intact humans ...
Houk, James +6 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Acta Neuropathologica Communications, 2018 Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder characterized by widespread oligodendroglial cytoplasmic inclusions of filamentous α-synuclein, and neuronal loss in autonomic centres, basal ganglia and cerebellar ...
Violetta Refolo +11 more
doaj +1 more source
Isolation, characterization, and substrate properties of the external limiting membrane from the avian embryonic optic tectum [PDF]
, 1990 The external limiting membrane of the avian embryonic optic tectum is isolated by mechanically separating the neuronal mesencephalon from the overlying mesenchymal tissue.
Adler +58 more
core +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source