Results 61 to 70 of about 26,837,992 (363)

Dual‐Phase C‐11 PiB PET Images for Detecting Tau Pathology in Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cerebral amyloid angiopathy (CAA) is a major cause of lobar intracerebral hemorrhage and cognitive dysfunction in the elderly, and frequently coexists with Alzheimer's disease and tau pathology. Dual‐phase 11C‐PiB PET detects amyloid deposition and cerebral perfusion changes and may have diagnostic value for identifying tau in CAA ...
Meng‐Ting Chiang, Chia‐Ju Liu, Bo‐Ching Lee, Ruoh‐Fang Yen, Hsin‐Hsi Tsai   +4 more
wiley   +1 more source

Bilateral traumatic hemorrhage of the basal ganglia

Chinese Journal of Traumatology, 2016
Hemorrhage of the basal ganglia is common in hypertensive patients, and most of the cases are spontaneous unilateral hemorrhage. Traumatic basal ganglia hemorrhage is uncommon, while bilateral hemorrhage of the basal ganglia after trauma is an extremely ...
Yun-Xu Zhang, Shu-Qin Wei, Yan-Yun Xing, Qi Liu, Wen-Jing He   +4 more
doaj   +1 more source

Deep brain stimulation with a computational model for the cortex-thalamus-basal-ganglia system and network dynamics of neurological disorders [PDF]

arXiv, 2021
Deep brain stimulation (DBS) can alleviate the movement disorders like Parkinson's disease (PD). Indeed, it is known that aberrant beta (13-30Hz)oscillations and the loss of dopaminergic neurons in the basal ganglia-thalamus (BGTH) and cortex characterize the akinesia symptoms of PD. However, the relevant biophysical mechanism behind this process still
arxiv  

Early Language Impairment as an Integral Part of the Cognitive Phenotype in Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Huntington's disease (HD) speech/language disorders have typically been attributed to motor and executive impairment due to striatal dysfunction. In‐depth study of linguistic skills and the role of extrastriatal structures in HD is scarce.
Arnau Puig‐Davi, Carla Franch‐Marti, Iñigo Ruiz‐Barrio, Frederic Sampedro, Jesus Perez‐Perez, Jordi A. Matias‐Guiu, Fernando Cuetos, Gonzalo Olmedo‐Saura, Laura Perez‐Carasol, Andrea Horta‐Barba, Ignacio Aracil‐Bolaños, Javier Pagonabarraga, Jaime Kulisevsky, Saul Martinez‐Horta   +13 more
wiley   +1 more source

Alterations of striatal indirect pathway neurons precede motor deficits in two mouse models of Huntington's disease

Neurobiology of Disease, 2017
Striatal neurons forming the indirect pathway (iSPNs) are particularly vulnerable in Huntington's disease (HD). In this study we set out to investigate morphological and physiological alterations of iSPNs in two mouse models of HD with relatively slow ...
Irene Sebastianutto, Maria Angela Cenci, Tim Fieblinger   +2 more
doaj  

Action-modulated midbrain dopamine activity arises from distributed control policies [PDF]

arXiv, 2022
Animal behavior is driven by multiple brain regions working in parallel with distinct control policies. We present a biologically plausible model of off-policy reinforcement learning in the basal ganglia, which enables learning in such an architecture.
arxiv  

The Basal Ganglia: More than just a switching device

CNS Neuroscience & Therapeutics, 2018
The basal ganglia consist of a variety of subcortical nuclei engaged in motor control and executive functions, such as motor learning, behavioral control, and emotion.
T. Florio, E. Scarnati, Ilaria Rosa, D. di Censo, B. Ranieri, A. Cimini, A. Galante, M. Alecci   +7 more
semanticscholar   +1 more source

Music Interventions in Hyperacute and Acute Stroke Patients: A Randomized Controlled Pilot Feasibility Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Music interventions have been shown to have beneficial effects on hemodynamic parameters, pain, and anxiety in various medical settings. However, music interventions in the setting of acute stroke have not been studied. The objective of this trial was to perform a pilot feasibility study of music interventions in the setting of acute
Jeffrey J. Fletcher, Allison Edberg, Ronald Grifka, Joan Westendorp, Augusto Elias, Jacquie Knott, Elizabeth Martin, Fazeel Siddiqui   +7 more
wiley   +1 more source

Opponent and bidirectional control of movement velocity in the basal ganglia

Nature, 2016
For goal-directed behaviour it is critical that we can both select the appropriate action and learn to modify the underlying movements (for example, the pitch of a note or velocity of a reach) to improve outcomes.
E. A. Yttri, J. Dudman
semanticscholar   +1 more source

Role of the Basal Ganglia in Balance Control

Neural Plasticity, 2005
In this review paper, we summarize the important contributions of the basal ganglia to the regulation of postural control. After a brief overview of basal ganglia circuitries, the emphasis is on clinical observations in patients with focal lesions in ...
Jasper E. Visser, Bastiaan R. Bloem
doaj   +1 more source