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Neuroimaging of Basal Ganglia in Neurometabolic Diseases in Children [PDF]

open access: goldBrain Sciences, 2020
Diseases primarily affecting the basal ganglia in children result in characteristic disturbances of movement and muscle tone. Both experimental and clinical evidence indicates that the basal ganglia also play a role in higher mental states.
Justyna Paprocka   +3 more
doaj   +2 more sources

Optimized AAV capsids for basal ganglia diseases show robust potency and distribution [PDF]

open access: yesNature Communications
Huntington’s disease and other disorders of the basal ganglia create challenges for biomolecule-based medicines given the poor accessibility of these deep brain structures following intracerebral or intravascular delivery.
D. E. Leib   +13 more
doaj   +2 more sources

Bilateral Basal Ganglia Calcification: Fahr's Disease [PDF]

open access: diamondCureus, 2019
Fahr's disease/syndrome is a condition defined as bilateral striato-pallido-dentate calcinosis, a neurodegenerative disease with radiological findings of symmetrical and bilateral idiopathic calcifications of the cerebellum, periventricular white matter, and basal ganglia. Clinical correlation with radiological and a calcium metabolism panel is crucial
Ooi, Hsein Wei   +4 more
openaire   +3 more sources

A case report of Fahr’s disease presenting with cerebellar ataxia [PDF]

open access: yesJournal of Research in Clinical Medicine, 2023
Fahr’s disease is a rare condition characterized by the symmetrical calcification of basal ganglia and dentate nuclei of the cerebellum calcification. It is usually manifested by involuntary movements and psychiatric symptoms. Ataxia has been reported as
Mohammad Yazdchi   +4 more
doaj   +1 more source

Diagnostic Evaluation of 99mTc-TRODAT-1 SPECT in Parkinsonism [PDF]

open access: yesJournal of Research in Clinical Medicine, 2021
Background Parkinsonism as a group of movement disorders, exhibit similar clinical presentation. Therefore, clinically differentiating these diseases is difficult. We investigated the diagnostic value of 99m Tc-TRODAT-1 SPECT in this setting.
Zahra Babaei Aghdam   +5 more
doaj   +1 more source

The Role of Vitamin D in Basal Ganglia Diseases

open access: yesJournal of Integrative Neuroscience, 2022
Objective: Vitamin D (VitD) has been shown to influence several cellular processes in the brain. The extent to which VitD plays a role in the pathomechanism of neuronal loss and dysfunction in basal ganglia diseases (BGDs) is still debated.
Carl Nikolaus Homann, Barbara Homann
doaj   +1 more source

Neuro-Immune Cross-Talk in the Striatum: From Basal Ganglia Physiology to Circuit Dysfunction

open access: yesFrontiers in Immunology, 2021
The basal ganglia network is represented by an interconnected group of subcortical nuclei traditionally thought to play a crucial role in motor learning and movement execution.
Andrea Mancini   +5 more
doaj   +1 more source

Basal ganglia role in learning rewarded actions and executing previously learned choices: Healthy and diseased states [PDF]

open access: yes, 2020
The basal ganglia (BG) is a collection of nuclei located deep beneath the cerebral cortex that is involved in learning and selection of rewarded actions. Here, we analyzed BG mechanisms that enable these functions.
Atwood, Brady   +2 more
core   +1 more source

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