Results 1 to 10 of about 99,722 (241)

Psychiatric aspects of basal ganglia diseases. [PDF]

Psychiatria Danubina, 2011
This review clarifies the fact that basal ganglia diseases are psychiatric as much as neurological diseases. It illustrates psychiatric aspects in Parkinson's disease and other hereditary basal ganglia diseases such as Wilson's disease, Huntington's chorea and others. In these diseases, psychological disorders can be difficult to diagnose, whether they
Mirela Vlastelica
openaire   +4 more sources

Basal ganglia role in learning rewarded actions and executing previously learned choices: Healthy and diseased states [PDF]

, 2020
The basal ganglia (BG) is a collection of nuclei located deep beneath the cerebral cortex that is involved in learning and selection of rewarded actions. Here, we analyzed BG mechanisms that enable these functions.
Atwood, Brady, Kuznetsov, Alexey, Mulcahy, Garrett   +2 more
core   +1 more source

Cerebral activations related to ballistic, stepwise interrupted and gradually modulated movements in parkinson patients [PDF]

, 2012
Patients with Parkinson's disease (PD) experience impaired initiation and inhibition of movements such as difficulty to start/stop walking. At single-joint level this is accompanied by reduced inhibition of antagonist muscle activity.
A Berardelli, A Berardelli, A Berardelli, A Nambu, A Nambu, AC Bostan, AC Kreitzer, AR Aron, AR Crossman, B Draganski, Bauke M. de Jong, Bernard A. Conway, BM de Jong, BM de Jong, C Rorden, Carolien M. Toxopeus, CD Marsden, CM Toxopeus, CM Toxopeus, D Eidelberg, DC Knill, DS Hoffman, E Gowen, ED Playford, EH Yeterian, EH Yeterian, FA Middleton, G Ebersbach, GE Alexander, GE Alexander, GN Lewis, Gopal Valsan, H Boecker, H Raptis, H Yu, HE den Ouden, HJ Groenewegen, J Hore, J Shires, JA Obeso, JC Rothwell, JD Kropotov, JF Kalaska, JM Kemp, JP Coxon, JS Freeman, JW Mink, JW Mink, JW Mink, JW Mink, K Kaneda, KA Josephs, KJ Friston, KJ Worsley, Klaus L. Leenders, LD Selemon, LK Teune, LL Rubchinsky, M Annett, M Beudel, M DeLong, M Jahanshahi, M Jahanshahi, M Jueptner, M Samuel, MH Schieber, MJ Frank, MM Amick, MM Hoehn, MR DeLong, MR DeLong, MS Matell, N Dounskaia, N Giladi, Natasha M. Maurits, NL Cerminara, O Rascol, O Sporns, P Joti, P Praamstra, P Redgrave, Paul L. Gribble, R Benecke, R Romo, RC Miall, RL Albin, RN Lemon, RS Turner, S Donovan, S Fahn, S Gauggel, S Grillner, S Hirano, S Jahfari, S Lehericy, S Luzzi, S Meunier, SE Leh, SP Wise, T Heida, T Ohyama, U Castiello, U Sabatini, VM Zatsiorsky, W Hauber, Y Jiang, Y Ma   +106 more
core   +4 more sources

Neuroimaging of Basal Ganglia in Neurometabolic Diseases in Children [PDF]

Brain Sciences, 2020
Diseases primarily affecting the basal ganglia in children result in characteristic disturbances of movement and muscle tone. Both experimental and clinical evidence indicates that the basal ganglia also play a role in higher mental states. The basal ganglia can be affected by neurometabolic, degenerative diseases or other conditions from which they ...
Justyna Paprocka, Magdalena Machnikowska-Sokołowska, Katarzyna Gruszczyńska, Ewa Emich-Widera   +3 more
openaire   +4 more sources

Binary and nonbinary description of hypointensity for search and retrieval of brain MR images [PDF]

, 2009
Diagnosis accuracy in the medical field, is mainly affected by either lack of sufficient understanding of some diseases or the inter/intra-observer variability of the diagnoses.
Cetin, Mujdat, Chen, Xiaojing, Ekin, Ahmet, Ercil, Aytul, Erçil, Aytül, Jasinschi, Radu, Unay, Devrim, van Buchem, Mark A., Çetin, Müjdat, Ünay, Devrim   +9 more
core   +1 more source

Segmental aging underlies the development of a Parkinson phenotype in the AS/AGU rat [PDF]

, 2016
There is a paucity of information on the molecular biology of aging processes in the brain. We have used biomarkers of aging (SA β-Gal, p16Ink4a, Sirt5, Sirt6, and Sirt7) to demonstrate the presence of an accelerated aging phenotype across different ...
Khojah, Sohair M., McGuinness, Dagmara, Payne, Anthony P., Shields, Paul G.   +3 more
core   +2 more sources

Genetic diagnosis of basal ganglia disease in childhood

Developmental Medicine & Child Neurology, 2022
AIMTo correlate clinical, radiological, and biochemical features with genetic findings in children with bilateral basal ganglia lesions of unknown aetiology, and propose a diagnostic algorithm for early recognition.METHODChildren with basal ganglia disease were recruited in a 2‐year prospective multicentre study for clinical, biomarker, and genetic ...
Heidy Baide‐Mairena, Laura Marti‐Sánchez, Anna Marcé‐Grau, Ana Cazurro‐Gutiérrez, Angel Sanchez‐Montanez, Ignacio Delgado, Antonio Moreno‐Galdó, Alfons Macaya‐Ruiz, Elena García‐Arumí, Belén Pérez‐Dueñas   +9 more
openaire   +3 more sources

Pathological regional blood flow in opiate-dependent patients during withdrawal: A HMPAO-SPECT study [PDF]

, 1998
The aims of the present study were to investigate regional cerebral blood flow (rCBF) in heroin-dependent patients during withdrawal and to assess the relation between these changes and duration of heroin consumption and withdrawal data.
Biersack, H. J., Broich, K., Danos, P., Grunwald, F., Hoflich, G., Kasper, S., Klemm, E., Krappel, C., Möller, Hans-Jürgen, Overbeck, B.   +9 more
core   +1 more source

From variome to phenome : pathogenesis, diagnosis and management of ectopic mineralization disorders [PDF]

, 2015
Ectopic mineralization - inappropriate biomineralization in soft tissues - is a frequent finding in physiological aging processes and several common disorders, which can be associated with significant morbidity and mortality.
De Vilder, eva, Vanakker, Olivier
core   +2 more sources

Lesch–Nyhan disease and the basal ganglia

Brain Research Reviews, 2000
The purpose of this review is to summarize emerging evidence that the neurobehavioral features of Lesch-Nyhan disease (LND), a developmental disorder caused by congenital deficiency of the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT), may be attributable to dysfunction of the basal ganglia.
Visser, J.E., Bär, P.R., Jinnah, H.A.
openaire   +3 more sources