Randomized controlled trial of adalimumab in patients with nonpsoriatic peripheral spondyloarthritis [PDF]
Objective. To evaluate the efficacy and safety of adalimumab in patients with active nonpsoriatic peripheral spondyloarthritis (SpA). Methods. ABILITY-2 is an ongoing phase III, multicenter study of adalimumab treatment.
Karunaratne, P Mahinda +5 more
core +1 more source
Study protocol: Comparison of the effect of treatment with Nonsteroidal anti- inflammatory drugs added to anti-tumour necrosis factor a therapy versus anti- tumour necrosis factor a therapy alone on progression of Structural damage in the spine over two years in patients with ankyLosing spondylitis (CONSUL) – an open-label randomized controlled multicenter trial [PDF]
Introduction There is some evidence that non-steroidal anti-inflammatory drugs (NSAIDs), in particular celecoxib, might possess not only a symptomatic efficacy but also disease-modifying properties in ankylosing spondylitis (AS), retarding the ...
Listing, Joachim +5 more
core +1 more source
Increasing smoking intensity is associated with increased disease activity in axial spondyloarthritis. [PDF]
A history of ever-smoking appears to be associated with a more severe disease phenotype in axial spondyloarthritis (axSpA). However, evidence is sparse for the effect of increased smoking exposure on disease outcomes or whether smoking reduction or ...
Challoner, B +4 more
core +1 more source
Outcome measures in ankylosing spondylitis [PDF]
Ankylosing spondylitis is a chronic and progressive disease involving predominantly the axial skeleton. It is insidious and potentially debilitating, compromising the quality of life of patients suffering from the disease.
Ciconelli, Rozana Mesquita [UNIFESP] +1 more
core +1 more source
Evaluation of dose reduction versus standard dosing for maintenance of remission in patients with spondyloarthritis and clinical remission with anti-TNF (REDES-TNF): study protocol for a randomized controlled trial [PDF]
Background: dose reduction schedules of tumor necrosis factor antagonists (anti-TNF) as maintenance therapy in patients with spondyloarthritis are used empirically in clinical practice, despite the lack of clinical trials providing evidence for this ...
Avendaño, Cristina +10 more
core +3 more sources
Decreased plasma levels of soluble CD18 link leukocyte infiltration with disease activity in spondyloarthritis [PDF]
INTRODUCTION: Spondyloarthritis (SpA) comprises a group of diseases often associated with HLA-B27 and characterized by inflammation of the entheses and joints of the axial skeleton.
Anders Kjærgaard +9 more
core +2 more sources
Objective To analyze the status and correlation factors of fatigue in patients with ankylosing spondylitis (AS), and provide a reference for improving the fatigue status of patients with AS.
Tiantian Sun +6 more
doaj +1 more source
Background and Objectives: The objective of our study was to describe the biopsychosocial profile of individuals diagnosed with axial spondyloarthritis (AxSpA) and to analyze how their clinical characteristics interact with disease activity.
Carlos Fernández-Morales +3 more
doaj +1 more source
Вміст циркулюючих ендотеліальних клітин в крові як маркер ендотеліальної дисфункції у хворих на анкілозивний спондилоартрит [PDF]
Актуальність: Відомо, що смертність серед пацієнтів з анкілозивним спондилоартритом (АС) в більшості випадків зумовлена сердцево-судинною патологією, яка в свою чергу опосердкована наявністю хронічного системного запалення, який вважають вагомим ...
Кошак, Б.А.
core
INTRODUÇÃO: A Espondilite Anquilosante (EA) é uma doença inflamatória crônica que acomete o esqueleto axial. Cursa com dor e incapacidade funcional. Para medir o impacto da EA na vida dos pacientes são utilizados questionários que avaliam a atividade da ...
Valderilio Feijó Azevedo +3 more
doaj +1 more source

