Results 31 to 40 of about 4,212 (173)

Sustained low functional impairment in axial spondyloarthritis (axSpA): which are the primary outcomes that should be targeted to achieve this?

Arthritis Research & Therapy, 2023
Objectives To (i) determine whether sustained disease activity states, as measured by Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Ankylosing Spondylitis Disease Activity Score (ASDAS), impact function, and (ii) evaluate ...
Walter P. Maksymowych, Robert D. Inman, Louis Bessette, Proton Rahman, Emmanouil Rampakakis, Odalis Asin-Milan, Meagan Rachich, Anne Marilise Marrache, Allen J. Lehman   +8 more
doaj   +1 more source

The effect of ixekizumab on axial manifestations in patients with psoriatic arthritis from two phase III clinical trials: SPIRIT-P1 and SPIRIT-P2

Therapeutic Advances in Musculoskeletal Disease, 2023
Background: Psoriatic arthritis (PsA) is a chronic inflammatory condition predominantly affecting the peripheral joints. However, some patients with PsA can experience axial involvement which is manifested with back pain and associated with increased ...
Atul Deodhar, Dafna Gladman, Rebecca Bolce, David Sandoval, So Young Park, Soyi Liu Leage, Peter Nash, Denis Poddubnyy   +7 more
doaj   +1 more source

AB0703 WHICH OF THE ASDAS OR BASDAI CORRELATES BETTER WITH PHYSICIAN GLOBAL ASSESSMENT? [PDF]

Annals of the Rheumatic Diseases, 2020
Background: Ankylosing Spondylitis Disease Activity score (ASDAS) was developed because of the limitations of Bath Ankylosing Spondylitis Disease Index (BASDAI) of being totally patient-derived with limited face and construct validity. ASDAS includes inflammatory markers that were aimed to increase its face validity by representing a different ...
K. Maatallah, W. Triki, H. Ferjani, D. Kaffel, W. Hamdi   +4 more
openaire   +1 more source

Preliminary definitions of ‘flare’ in axial spondyloarthritis, based on pain, BASDAI and ASDAS-CRP: an ASAS initiative [PDF]

Annals of the Rheumatic Diseases, 2016
Flares may be used as outcomes in axial spondyloarthritis (axSpA) trials or observational studies. The objective was to develop a definition for 'flare' (or worsening) in axSpA, based on validated composite indices, to be used in the context of clinical trial design.(1) Systematic literature review of definitions of 'flare' in published randomised ...
Gossec, Laure, Portier, Agnès, Landewé, Robert, Etcheto, Adrien, Navarro-Compán, Victoria, Kroon, Féline, van Der Heijde, Désirée, Dougados, Maxime   +7 more
openaire   +3 more sources

Comparison of Ankylosing Spondylitis Disease Activity Score and Bath Ankylosing Spondylitis Disease Activity Index tools in assessment of axial spondyloarthritis activity

Rheumatology
Axial spondyloarthritis (axSpA) is an inflammatory joint disease, in which the dominant symptom is inflammatory back pain. It affects approximately 1% of the population, with a higher incidence in males.
Katarzyna Małgorzata Wiąk-Walerowicz, Ewa Wielosz   +1 more
doaj   +1 more source

OPTIMIZING EXISTING TOOLS FOR REACHING AN ADEQUATE DISEASE CONTROL IN PATIENTS WITH SPONDYLOARTHRITIS [PDF]

Romanian Journal of Rheumatology, 2016
Background/Objective. Disease activity in spondyloarthritis (SpA) is evaluated through conventional scores such as BASDAI or ASDAS. The aim of this study was to determine disease activity in SpA patients under biological therapy with further assessment ...
Claudia Deaconu, Daniela Opris, Diana Mazilu, Laura Groseanu, Andreea Borangiu, Saulescu Ioana, Alexandra Peltea, Magdalena Negru, Cosmin Constantinescu, Violeta Vlad, Violeta Bojinca, Andra Balanescu, Denisa Predeteanu, Ruxandra Ionescu   +13 more
doaj   +1 more source

Eligibility criteria for biologic disease-modifying antirheumatic drugs in axial spondyloarthritis: going beyond BASDAI

RMD Open, 2020
Objectives To compare definitions of high disease activity of the Ankylosing Spondylitis Disease Activity Score (ASDAS) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in selecting patients for treatment with biologic disease-modifying ...
Sofia Ramiro, Elsa Vieira-Sousa, Alexandre Sepriano, Helena Santos, Jose Marona, Santiago Rodrigues-Manica, Fernando Pimentel-Santos, Ana Filipa Mourão, Nélia Gouveia, Jaime Cunha Branco, Filipe Vinagre, João Tavares-Costa, João Rovisco, Miguel Bernardes, Nathalie Madeira, Rita Cruz-Machado, Raquel Roque, Joana Leite Silva, Mary Lucy Marques, Raquel Miriam Ferreira   +19 more
doaj   +1 more source

Axial spondyloarthritis in men and women

Научно-практическая ревматология
The work of recent decades has changed the idea that axial spondylitis (axSpA) is an exclusively “male” disease. However, at present, when deciding on further treatment tactics, gender differences in the course of the disease and response to treatment ...
E. V. Ilinykh, T. V. Dubinina, A. O. Sablina, E. M. Agafonova, K. V. Sakharova, A. B. Demina, I. A. Andrianova, S. I. Glukhova, Sh. F. Erdes   +8 more
doaj   +1 more source

Disease activity indexes might not capture the same disease aspects in males and females with ankylosing spondylitis: A real-world nationwide analysis

Frontiers in Medicine, 2022
BackgroundTo evaluate gender differences in disease activity and health status (HS) in patients with radiographic axial spondyloarthritis (r-axSpA)/ankylosing spondylitis (AS).MethodsAncillary analysis of the MIDAS study, an observational, non ...
Cristina Fernández-Carballido, Vega Jovaní, Emma Beltrán Catalán, Manuel José Moreno-Ramos, Jesús Sanz Sanz, Adela Gallego, M. Luz García Vivar, José Manuel Rodríguez-Heredia, Cristina Sanabra, Carlos Sastré   +9 more
doaj   +1 more source

Effect of Intravenous Golimumab on Fatigue and the Relationship with Clinical Response in Adults with Active Ankylosing Spondylitis in the Phase 3 GO-ALIVE Study

Rheumatology and Therapy, 2023
Introduction We studied the effect of intravenous (IV)-golimumab on fatigue and the association of fatigue improvement with clinical response post hoc in adults with active ankylosing spondylitis (AS) in the GO-ALIVE trial.
Atul Deodhar, Natalie J. Shiff, Cinty Gong, Eric K. H. Chan, Elizabeth C. Hsia, Kim Hung Lo, Alianu Akawung, Lilianne Kim, Stephen Xu, John D. Reveille   +9 more
doaj   +1 more source