Results 201 to 210 of about 8,961,288 (283)

Health behaviours and telomere biology in severe mental disorders. [PDF]

Transl Psychiatry
Mlakar V, Di Forti M, Halff EF, Srivastava DP, Akkouh I, Djurovic S, Martin-Ruiz C, Quintana DS, Birkenæs V, Steen NE, E G Ormerod MB, Andreassen OA, Aas M.   +12 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Statistical indirect associations of sleep disturbance and GAD symptoms in the relationship between childhood trauma and non-suicidal self-injury in adolescents with depression. [PDF]

Front Psychol
Shao H, Xie Z, Wu Y, Yang T, Zhang M, He K.   +5 more
europepmc   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Preventing children's care entry: an umbrella review of the risks, protective factors, and interventions.

Child Youth Serv Rev
Rodgers M, Chen Y, Bennett D, Black M, Hankinson M, Liu Y, Marshall D, Taylor-Robinson D, Sowden A.   +8 more
europepmc   +1 more source

Effectiveness of an In-Hospital Stroke Bypass System for Endovascular Treatment: A Comparative Study. [PDF]

J Neuroendovasc Ther
Kumagai J, Takahata S, Nakayama R, Kondo R, Naka K, Iijima T.   +5 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Perinatal interventions for parents with exposure to adverse childhood experiences: A narrative review of suitability for implementation in primary care. [PDF]

Infant Ment Health J
Chen JJ, Magnuson K, Edgar VB, Stewart SM.   +3 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Weighting Bayesian information in human judgment under uncertainty: a hierarchical theory of cognitive biases. [PDF]

Front Psychol
Kopp B.
europepmc   +1 more source