Base Composition, Codon Usage, and Patterns of Gene Sequence Evolution in Butterflies. [PDF]
Genome Biol Evol, 2023 Näsvall K +3 more
europepmc +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
A method for automatic gamelan music composition
IJAIN (International Journal of Advances in Intelligent Informatics), 2016 Aim of this study is designing a method for automatic gamelan music composition using rule-base expert system approach. The program is designed for non-expert user in order to help them composing gamelan music or analyzing their composition to achieve ...
Khafiizh Hastuti, Khabib Mustafa
doaj +1 more source
On the Base Composition of Transposable Elements. [PDF]
Int J Mol Sci, 2022 Boissinot S.
europepmc +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Domain ontology knowledge base and its application in nursing practical domain
Huli yanjiu, 2017 It introduced the concept，composition and construction method of ontology knowledge base,and its application in the field of nursing practice at home and abroad.combined with China’s nursing information foundation，the feasibility of nursing practice to ...
ZHENG Jie
doaj
Purifying selection against spurious splicing signals contributes to the base composition evolution of the polypyrimidine tract. [PDF]
J Evol Biol, 2023 Yıldırım B, Vogl C.
europepmc +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Inverted base composition skews and discontinuous mitochondrial genome architecture evolution in the Enoplea (Nematoda). [PDF]
BMC Genomics, 2022 Zou H +7 more
europepmc +1 more source